We investigated the quenching activity of capsaicin （CAP） against singlet oxygen （1O2） using nano second time-resolved laser flash photolysis. As a result, the 1O2 quenching rate constants （kQ） of CAP was 7.7×105 M－1sec－1, which was found to be much less active than that of α-tocopherol （1.9×108 M－1sec－1） and 2, 5-diphenyl-3, 4-benzofuran （2.8×109 M－1sec－1）. However, CAP quenches with 1O2 more rapidly than the natural decay rate of 1O2 （8.3×104 sec－1） in ethanol. Next, we measured the kQ values, the guaiacol derivatives, which make up the main skeleton of CAP, and discussed the 1O2 - quenching active site of CAP. Consequently, N-benzylacetamide, a related compound which does not have the phenol moiety of CAP but does have acetamide moiety, did not show 1O2 quenching activity. This result indicates that the phenolic hydrogen of CAP is the site of 1O2 quenching activity. Furthermore, it was also clarified that the 1O2 quenching activity of CAP is affected by the type of side chain with para position of the hydroxyl group of CAP.
〔Objectives〕The purpose of this research is to clarify the needs of home care patients who require the care from Community Nutrition Support Team and their family members, and to identify the medical profession that can meet the needs of the aforementioned groups of people. 〔Methods〕Firstly, the needs of home care patients and their families regarding food and nutrition were investigated with content analysis. Secondly, specific professions related to those needs were clarified by distinctive-feature analysis with text mining through the investigation on medical professions regarding nutrition support. 〔Results〕Total five types of needs and several professions which are closely related to those needs were identified. By classifying the needs and professions, three types of layers were defined as follows; “Treatment” team formed mainly by doctors which is focused on “building enough strength to stay home”; “Intake/Swallowing” team consists of dental professionals and rehabilitation professionals to support “nutrition oral ingestion”; and “Nutrition Support” team with registered dietitians which aims to “satisfy both taste and nutrition.” 〔Conclusion〕We can expect to have more efficient and effective nutrition support even in a medical field with limited number of personals by considering the classification of needs and positioning of proper professionals to form the medical team for home care.