JOURNAL OF THE KYORIN MEDICAL SOCIETY

1. Synaptic potentials were recorded in identified extraocular motoneu-rons in anesthetized cats, following stimulation of ampullary nerves of the anterior and posterior semicircular canals. 2. Superior rectus motoneurons received disynaptic EPSPs and IPSPs following stimulation of the bilateral ampullary nerves of the anterior and posterior semicircular canals, respectively. In the inferior rectus motoneurons, the effects of anterior and posterior semicircular canal stimulation were a mirror image of those on superior rectus motoneurons. 3. Inferior oblique motoneurons developed disynaptic EPSPs and IPSPs following stimulation of the ampullary nerves of contralateral anterior and ipsilateral posterior semicircular canals, respectively. In addition, some inferior oblique motoneurons displayed disynaptic IPSPs following stimulation of the contralateral ampullary nerve of the posterior semicircular canal. In the superior oblique (trochlear) motoneurons, disynaptic EPSPs and IPSPs were recorded after stimulation of the contralateral posterior and ipsilateral anterior semicircular canals, respectively. 4. There was no significant connection between the ampullary nerves of the vertical semicircular canals and motoneurons innervating lateral and medial rectus muscles.

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In studying medical terms etymologically, there has hitherto been a general tendency to discuss etymology within the limits of Greek and Latin only. The author tried to enlarge the scope of such discussions of English medical terms through achievements of the Indo-European comparative linguistics. In the present report, the author thereby tried to broaden and also deepen the knowledge of medical English through the comparative study of cognate relationships between medical terms of Greek-Latin origin and English words of Germanic origin in accordance with the law of Indo-European sound correspondences. This method of studying Indo-European cognate words shed a new light on complicated medical terminology, and was helpful in understanding medical English from a simply fundamental viewpoint-namely, from Proto-Indo-European common roots.

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This study is to attempt the noninvasive measurement of P-V relation in the venous system of human forearm segments through a simultaneous measurement of electrical admittance and cuff pressure change following venous occlusion in 36 healthy subjects (29 males and 7 females ; 20-46 years old). Firstly, volume changes measured by an admittance (&lrtri;V_Y) and a coven-tional type of water-displacement plethysmography (&lrtri;V) were compared. The correlation coefficient and linear regression equation were r=0.986 and &lrtri;V_Y=0.920 &lrtri;V+0.44, respectively, and 91.9% of total data (n=242) were within±20% error range. Secondly, venous pressure change measured by inserting hypodermic needle into the vein (&lrtri;P_V) were compared with cuff-pressure changes (&lrtri;P_<cuff>). The results were r=0.967 and P_V=0.790 P_<cuff>+3.55, and 96.4% of the total data (n=192) were within±20% error range. It is suggested through these results that P-V relation in the venous system can be noninvasively determined by the simultaneous measurement of electrical admittance and cuff-pressure in human limb segments.

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An apparatus by a combination of atomic absorption spectrometer (AAS) and high performance aqueous gel permeation chromatograph (HPAGPC) was developed and it was used a clinical diagnosis of anemia associated with some metal elements (Fe, Cu and Zn) in serum and/or blood as an application to a medical field. The diagnosis was investigated on their chromatograms showing the molecular weight distributions of some metal containing compounds in serum and/or blood and this proposed method was a new approach to a clinical diagnosis of human diseases. Separation of metal containing compounds in serum and/or blood was effected on one G 4000 SW column, two G 3000 SW columns and one G 2000 SW column (Toyo Soda, Tokyo) connected in series using pH 7.3, 1/15 M phosphate buffer solution as the mobile phase. AAS was also used for the high sensitive detection to their metal containing compounds. The detection limit, the analytical time and the precision by the proposed method were 10^<-7> M, within 90 min and within 2 % in terms of coefficient of variation, respectively. Therefore, their metal containing compounds could be effectively determined for the clinical diagnosis of the human diseases by the proposed method. A clinical diagnosis of anemia by determination of their chromatograms of the metal containing compounds was mede simpler, more effective and easier in comparison with that by the usual method for which serum iron and total iron binding capacity and/or unsaturated iron binding capacity were determined and compared. Furthermore, several new peaks of metal containing com-pounds were detected by the present method and their peaks were also useful for the diagnosis of anemia. The same results s above mentioned about iron containing compounds were obtained by the measurements of their chromatograms of copper and zinc containing compounds in serum.

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