巻号一覧
36 巻 (1988)
- 5 号 p. 187-
- 4 号 p. 169-
- 3 号 p. 87-
- 2 号 p. 35-
- 1 号 p. 1-
36 巻, 2 号
選択された号の論文の5件中1～5を表示しています
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報文
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富澤 儀一, 西 功, 永野 昭則, 大岩 弘典, 橋本 昭夫, 小此木 国明, 鈴木 信哉1988 年 36 巻 2 号 p. 35-48
発行日: 1988年
公開日: 2007/05/01
ジャーナル フリーAn N2 washout measurement was applied in the hyperbaric heliox environment to estimate lung ventilation distribution. In this procedure, N2 lung content was flushed by the inhalation of an N2 free gas. The purpose of the measurement was to investigate change in ventilation distribution in a hyperbaric environment which was created by the use of a deep diving simulator. Physiological parameters measured were respiratory gas concentrations (FN2, FAr, FCO2, FO2, FHe and FH2O), respiratory flow rate and temperature.
The respiratory gas concentrations, flow, and temperature were simultaneously measured in a breath-by-breath fashion in the full pattern and digitally recorded with high accuracy and response. Concentration and flow of each breath were examined on a CRT and corrected as required prior to recording on a data base system. The corrections were made to compensate for gas leakage to and from the gas circuit, the electronic drift and noise.
In this experiment, a mass spectrometer to analyze respiratory gas concentrations and an amplifier to enhance readings, were placed outside the hyperbaric chamber for reading of a Fleish pheumotachometer and thermistor sensors.
In order to be analyzed, it was necessary to introduce the respiratory gas sample through the large pressure difference. Concentrations of physiological gases were decreased with the increased ambient pressure of He balance.
Other technical points to be resolved were mass spectrometer and flow meter calibrations under hyperbaric conditions. The computer-assisted measurement was also used to conduct the complex procedure. The technical problems which were encountered are discussed in this study.
The experimental results obtained at 12, 18 and 31 ATA (equivalent to depths of 110, 170 and 300m) are shown in comparison with results in the atmospheric environment.抄録全体を表示PDF形式でダウンロード (795K) -
吉田 佳一, 田中 耕一, 井戸 豊, 秋田 智史, 吉田 多見男1988 年 36 巻 2 号 p. 49-58
発行日: 1988年
公開日: 2007/05/01
ジャーナル フリーA new gradient electric field type ion reflector for a time-of-flight mass spectrometer has been developed in order to improve mass spectral resolution by time focusing. A retarding field in the reflector has two terms; One term proportional to penetrating depth of ions into the reflector and a constant term. In the TOF mass spectrometer consisting of a free ion drift region and the ion reflector, the motion of the same m/z ions is quasi-single oscillation of the same period. Therefore the flight times of the same m/z ions are focused to a constant, even if the initial kinetic energy of the emitted ions are distributed. In this paper, the theory of time focusing effect, the results of the computer simulation and the experimental results with laser desorption are reported.抄録全体を表示PDF形式でダウンロード (531K) -
吉田 多見男, 田中 耕一, 井戸 豊, 秋田 智史, 吉田 佳一1988 年 36 巻 2 号 p. 59-69
発行日: 1988年
公開日: 2007/05/01
ジャーナル フリーA laser desorption time-of-flight (TOF) mass spectrometer has been developed in order to analyze non-volatile, thermally labile and high mass organic compounds, in which the “gradient electric field type ion reflector” was used for time focusing. Higher detection sensitivity for high mass ions was achieved by adding a blind type ion-electron converter to the micro-channel plate (MCP) ion detector. Two TOF spectrum measurement systems were constructed, with which two measurement methods called as “AD method” and “TDC method” were able to be selected to obtain the spectrum sensitively and accurately in a short time.
For sample preparation, “metal fine powder and glycerol matrix” method was confirmed to be very effective to increase the yield of high mass molecular ions.
This mass spectrometer was successfully applied to the detection of quasi-molecular ions from many high mass organic compounds, such as Cytochrome-C (mol. wt. 12,384), Bovine Trypsin (mol. wt. ~24,000) and Carboxypeptidase-A (mol. wt. 34,472).抄録全体を表示PDF形式でダウンロード (598K) -
Akiyo Sakushima, Sansei Nishibe, Tadahiro Takeda, Yukio Ogihara1988 年 36 巻 2 号 p. 71-80
発行日: 1988年
公開日: 2007/05/01
ジャーナル フリーFlavonoid glycosides (22 compounds) were measured by fast atom bombardment, and the positive and negative ion mass spectra were compared. The mass spectra showed clear molecular ion species. Fast atom bombardment mass spectrometry provided useful information for the structural elucidation of flavonoid glycosides.
Positive ion spectra in particular were useful for flavonol 3,7-O-diglycosides, while the negative ion spectra were useful for flavonoid glycoside methyl ether.抄録全体を表示PDF形式でダウンロード (472K)
技術報告
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Takemichi Nakamura, Hidemi Nagaki, Takeshi Kinoshita1988 年 36 巻 2 号 p. 81-86
発行日: 1988年
公開日: 2007/05/01
ジャーナル フリーA mixture of caesium iodide, sodium iodide, and glycerol was found to be a convenient calibrant for routine fast atom bombardment mass analysis. The mixture can be used for both positive and negative ion modes, and at a mass range around m/z 10 to 2,500 with reasonable mass accuracy.抄録全体を表示PDF形式でダウンロード (302K)
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