Online ISSN : 1884-6440
Print ISSN : 0385-1036
ISSN-L : 0385-1036
14 巻, 3 号
選択された号の論文の8件中1~8を表示しています
  • 生体触媒活性の電気制御
    相澤 益男
    1989 年 14 巻 3 号 p. 158-163
    発行日: 1989/05/01
    公開日: 2011/03/04
    ジャーナル フリー
  • 山根 恒夫
    1989 年 14 巻 3 号 p. 164-176
    発行日: 1989/05/01
    公開日: 2011/03/04
    ジャーナル フリー
    A novel membrane bioreactor suitable for liquid-liquid two phase enzymatic reactions is reviewed. The membrane bioreactor is based on the principle of liquid-liquid contact mode, and enables three points : (1) simultaneous achievement of both reaction and liquid-liquid separation, (2) containment of the enzyme in the bioreactor, and (3) realization of fully continuous operation. Engineering aspects are discussed such as kinds of membrane used, types of module applied, methods of enzyme immobilization, its scale-up etc. Several types of reaction to which the enzyme membrane bioreactor with liquid-liquid contact mode is successfully applied are introduced such as hydrolysis of fats and oils, synthesis of glycerides, glycerolysis of fats, transphosphatidylation of phospholipids, and chiral resolution. Enzymes involved in these reactions are lipase, phospholipase and peptidase.
  • 関 実, 大岸 治行
    1989 年 14 巻 3 号 p. 177-185
    発行日: 1989/05/01
    公開日: 2011/03/04
    ジャーナル フリー
    Research on organic acid production using bioreactors with membranes was reviewed. Firstly, procedures of organic acid production in biochemical processes were presented. Secondly, recent topics about application of membranes to bioreactors were discussed. Thirdly, research on membrane bioreactors (MBR) to produce organic acids e. g. acetic acid, lactic acid, fatty acids etc. were presented. Finally, our research on muconic acid production using a MBR was shown.
  • 石川 治男
    1989 年 14 巻 3 号 p. 186-195
    発行日: 1989/05/01
    公開日: 2011/03/04
    ジャーナル フリー
    In this article, recent topics of enzyme membrane reactors are reviewed. Membrane reactors can be classified into five types, according to whether the enzymes are free or immobilized, and whether the driving force for the mass transfer is pressure or diffusion. The functions of membranes of each type of the reactors are discussed and some typical reactors and reaction systems are described. The relative merits of pressure-driven reactors or reactors in an ultrafiltration mode in which the mass transfer occurs by pressure-driven convection and diffusional reactors in which the mass transfer occurs by diffusion are extensively discussed on the basis of the reactor performance. Previously published theoretical and experimental results and new additional calculations show that from the viewpoint of productivity and operational problems with reactors, reactors in an ultrafiltration mode are not necessarily superior to diffusional reactors.
  • Haruo Ishikawa, Katsuo Kurose, Tetsuya Murakami, Tohru Ishii, Haruo Hi ...
    1989 年 14 巻 3 号 p. 196-204
    発行日: 1989/05/01
    公開日: 2011/03/04
    ジャーナル フリー
    A new membrane reactor concept which can shift the equilibria in reversible reactions can and drive the reactions to high conversion beyond that attainable in a conventional reactor was developed. The reactor is equipped with a composite of a catalytic membrane and a permselective membrane such as a supported liquid membrane through which the reactant is more permeable than the products and furthermore transfers actively to the reaction zone in the catalytic membrane. For a simple first-order reversible reaction, the conversion is theoretically examined. Analysis showed that the conversion exceeds sharply the thermodynamically obtainable maximum conversion or one obtainable in a conventional reactor, and the reaction proceeds almost irreversibly even if the equilibrium constant is small.
  • 田中 雅紀, 史 仲平, 清水 和幸, 飯島 信司, 小林 猛
    1989 年 14 巻 3 号 p. 205-210
    発行日: 1989/05/01
    公開日: 2011/03/04
    ジャーナル フリー
    Sporolactobacillus inulinus was cultured in a bioreactor equipped with a hollow fiber module, and continuous production of D-lactate was examined. In batch culture, concentration of D-lactate produced was estimated on line with the aids of a pulse counter and a personal computer from the amount of alkaline solution used for neutralizing the medium. When this monitoring system was applied to the hollow fiber bioreactor, the estimated lactate concentration was slightly lower than the measured one. In this culture, ammonium ion produced by the microorganism disturbed the estimation.However, by reducing yeast extract concentration in the medium or by introducing a suitable correction factor in the equation for estimation, a fairly good estimation followed by the good control of the lactate concentration could be attained. Furthermore, the cell concentration was also monitored by a turbidimeter and controlled at a desired level by removing cells automatically from the fermentor. The specific growth rate and the lactate production rate were controlled at constant values by keeping both cells and lactate concentrations constant.
  • Tadashi Uragami, Tomoyuki Aketa
    1989 年 14 巻 3 号 p. 211-216
    発行日: 1989/05/01
    公開日: 2011/03/04
    ジャーナル フリー
    An urease immobilizing membrane was prepared by ultrafiltrating a mixture consisted of quarternized chitosan, sodium polyacrylate and urease in an aqueous NaBr solution. Permeation and hydrolysis characteristics of aqueous urea solutions through the urease immobilizing membrane was kinetically investigated under various conditions. A rate of hydrolysis of urea through the urease immobilizing membrane corresponded to the Michaelis-Menten type reaction. Kinetic data for the hydrolysis of urea through this membrane were discussed by comparing with those for the hydrolysis of urea in a batch reaction using native urease.
  • 宮脇 長人, 藤井 智幸, 矢野 俊正
    1989 年 14 巻 3 号 p. 217-219
    発行日: 1989/05/01
    公開日: 2011/03/04
    ジャーナル フリー
    As a typical example for the product separation in bioreactors to produce neutral amino acids from the corresponding organic acids, separation of the mixture of lactate and L-alanine was attempted by the method with negatively charged sulfonated polysulfone reverse osmosis membrane and by the electrodialysis with ion exchange membranes. By one step electrodialysis, lactate and L-alanine could be completely separated from each other. The same method will be commonly applicable to the most of bioreactor processes for neutral amino acids being investigated extensively.
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