巻号一覧
44 巻 (2019)
- 6 号 p. 276-
- 5 号 p. 210-
- 4 号 p. 142-
- 3 号 p. 92-
- 2 号 p. 40-
- 1 号 p. 2-
44 巻, 3 号
選択された号の論文の10件中1～10を表示しています
- |<
- <
- 1
- >
- >|
特集：膜学会若手特集号
-
長尾 耕治郎2019 年 44 巻 3 号 p. 92-95
発行日: 2019年
公開日: 2019/06/08
ジャーナル 認証ありI have been studying the underlying mechanisms of transport and metabolism of biological membrane lipids in mammals. Recently, I initiated research using Drosophila melanogaster and other non–model animals to understand the roles of biological membrane lipids. On account of the development in technologies related to DNA sequencing, genome editing, and lipid analysis, the analysis of the biological membrane lipids of small and non–model animals, which have unique and unrevealed features, is now feasible.抄録全体を表示PDF形式でダウンロード (672K) -
田代 陽介2019 年 44 巻 3 号 p. 96-100
発行日: 2019年
公開日: 2019/06/08
ジャーナル 認証ありMany bacteria secrete spherical membranal nanoparticles from bacterial surface to extracellular milieu. These liposome– like particles are called as “outer membrane vesicles (OMVs)” or “membrane vesicles (MVs)”. They have important roles in several biological functions, including pathogenesis, microbial interaction, horizontal gene transfer and efflux of cellular substances. Recent studies have indicated that microbial vesicles have prospective potentials for applications such as therapeutic vaccines and drug delivery systems. In this review, I show the current understanding of vesicle functions, biogenesis and applications.抄録全体を表示PDF形式でダウンロード (673K) -
扇田 隆司2019 年 44 巻 3 号 p. 101-104
発行日: 2019年
公開日: 2019/06/08
ジャーナル 認証ありPathogenic bacteria deliver effector proteins directly into host cells via type III secretion system (T3SS) to prime the host cell environment for infection. Thus T3SS inhibitor would potently suppress bacterial infection. For molecular design of T3SS inhibitor, clarification of the protein transport mechanism of T3SS is required. We previously demonstrated that T3SS needle rotates by proton–motive force (PMF) and effector transport of T3SS is suppressed by inhibition of needle rotation. In this review, we summarize the recent knowledge about effector transport of T3SS and introduce our novel model of effector transport mechanism of T3SS based on our findings.抄録全体を表示PDF形式でダウンロード (642K) -
池田 義人2019 年 44 巻 3 号 p. 105-108
発行日: 2019年
公開日: 2019/06/08
ジャーナル 認証ありIn this paper, I would like to look back at my academic life so far. I have studied biochemistry of resistin belonging to the adipokine family as my graduate work. After getting a Ph.D. from Kyoto Pharmaceutical University in 2014, I started as assistant professor at department of Pharmacy in Shiga University of Medical Science Hospital. Studies for the elucidation of the role of phospholipids in bile and the mechanism of ABCB4 mediated phospholipid efflux are my current research subjects.抄録全体を表示PDF形式でダウンロード (708K) -
林 啓太2019 年 44 巻 3 号 p. 109-114
発行日: 2019年
公開日: 2019/06/08
ジャーナル 認証ありSelf–assembled surfactant aggregates, such as micelles and vesicles, have been investigated for their application, such as a drug carrier. These aggregates have individual properties, which are dependent on the chemical structure of surfactants, formation of aggregates, etc., and these properties are evaluated by various kinds of evaluation methods. It is important to systematically understand these properties, and to compile a database of aggregates. This database helps to design or choose an optimal aggregate to apply as a drug carrier.抄録全体を表示PDF形式でダウンロード (902K) -
中川 敬三2019 年 44 巻 3 号 p. 115-120
発行日: 2019年
公開日: 2019/06/08
ジャーナル 認証ありTwo–dimensional (2D) nanosheet materials with unique atomic thickness have become emerging building blocks for separation membranes. Recently, the separation membranes utilizing a variety of 2D nanosheet materials have been developed, and their fabrication methods, membrane performances as well as permeation mechanisms have been demonstrated. In this review, recent developments of 2D nanosheet membranes for liquid separation with three basic forms: nanoporous membrane, layered membrane and hybrid membrane are summarized. The promising research areas are highlighted and future directions are briefly discussed.抄録全体を表示PDF形式でダウンロード (1017K) -
金指 正言2019 年 44 巻 3 号 p. 121-125
発行日: 2019年
公開日: 2019/06/08
ジャーナル 認証ありAmorphous silica membrane has loose structure in comparison with cristobalite crystal structure, so that helium and hydrogen with small molecular size can permeate through amorphous structure. The potential for thin layer formation of less than 100 nm via chemical vapor deposition (CVD) and sol–gel method in comparison with other inorganic materials can dramatically improve He and H2 permselectivity. Here, sol–gel derived silica membranes are reviewed in terms of control of silica network size, which is important issue for a practical application of amorphous silica membranes in industry. The spacer method utilizing bridged alkoxide with organic groups between 2 Si atoms and fluorine doping into amorphous structure is introduced.抄録全体を表示PDF形式でダウンロード (952K) -
安川 政宏, 垣花 百合子, 比嘉 充2019 年 44 巻 3 号 p. 126-129
発行日: 2019年
公開日: 2019/06/08
ジャーナル 認証ありA research center focusing on salinity gradient energy (SGE), “Blue Energy center for SGE Technology (BEST)”, was newly established in Yamaguchi University in July 2018. This center is forging ahead membrane–based researches utilizing SGE towards its future’s implementation. In BEST, there are three research groups: (1) SGE conversion group, (2) Water hydrolysis group and (3) Water treatment group. Here, we introduced one of BEST ’s researches, a direct hydrogen production technique from seawater and sewage treated water by reverse electrodialysis (RED–H2 system). Since Yamaguchi is one of innovative prefectures for hydrogen applications, there is a good opportunity to generate CO2–free hydrogen (and oxygen) by the RED–H2 system at the municipal wastewater plant especially in Shunan city.抄録全体を表示PDF形式でダウンロード (766K)
原 著
-
小坂 秀斗, 中田 孝広, 田島 史郎, 上田 太郎, 後藤 雅宏2019 年 44 巻 3 号 p. 130-135
発行日: 2019年
公開日: 2019/06/08
ジャーナル フリーBioactive macromolecules are receiving great interest due to their versatile functions in living life, and especially, they have been extensively examined in medical application. In most cases, they are administered by mouth or injection, which accompanied with some drawbacks such as digestion in organs and the first–pass effect, etc. Although transdermal administration is a promising methodology that enables successful administration without these drawbacks, transdermal delivery of bioactive macromolecules is inhibited by a barrier function of Stratum Corneum (SC). To overcome the barrier function, we prepared reverse micelle formulation (RMF), in which bioactive macromolecules are encapsulated in reverse micelles. A model bioactive macromolecule, Heparinoid (HD), was successfully encapsulated inside the aqueous core of reverse micelles, and RMF was proven to be stable for more than 6 months at 40 ℃. RMF showed 100 times higher skin permeability of HD compared to its aqueous solution, which verifies the effectiveness of RMF as a transdermal administration carrier for bioactive macromolecules.抄録全体を表示PDF形式でダウンロード (896K)
製品& 技術
-
石橋 亮2019 年 44 巻 3 号 p. 136-139
発行日: 2019年
公開日: 2019/06/08
ジャーナル 認証ありWith the increasing threat of global water scarcity, reverse osmosis (RO) membrane is being accepted for the applications in desalination or waste water reuse. Moreover, the global water environmental is suffering from declining source water quality and increasing discharge requirements. As a solution, industrial water users are recycling and reusing more and more of limited water available to them. However, such water contains higher salts and organic contamination than fresh water sources, and thus fouling of RO system is an unavoidable challenge. Fouling of RO membrane leads to frequent chemical cleanings, system down time and high energy consumption.
In this report, our newest fouling resistance membrane, DOW FILMTECTM FORTILIFETM CR100 is introduced. Performance of this elements was compared with other fouling resistance elements by side-by-side plot test, and showed high fouling resistant of lower pressure drop and less CIP frequency. This demonstrates that this element would be an essential tool to solve challenges of water抄録全体を表示PDF形式でダウンロード (7603K)
- |<
- <
- 1
- >
- >|