We report three cases of sebaceous carcinoma of the eyelid. One of them, a 44-year-old women, had a tumor on the left upper eyelid. She had undergone surgery in several times as a sty. We removed surgically and reconstructed with the lower eyelid switch flap, but the tumor reappeard 7 months after the first operation. Pathological diagnosis was sebaceous carcinoma. Wide excision and upper eyelid reconstruction were performed as secondary switch flap. Additional radiation of 50Gy was applied to the lesion, followed by chemotherapy. No local recurrence was seen during the follow-up period of 3 years.

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A 12 year-old girl with the right thalamic tumor was referred from acute obstructive hydrocephalus and intratumoral hemorrhage. MRI revealed that the tumor showed a iso signal intensity on T1 weighted image, a high signal intensity on T2 weighted image itself, and no Gadolinium enhancement, showing the clear margin. Neuroendoscopic biopsy, the 3rd ventriculostomy, and Ommaya reservoir's placement were performed under general anesthesia for making the histological diagnosis and treatment of obstructive hydrocephalus. The histological diagnosis was anaplastic astrocytoma, Firstly, IMR(interferon β, MCNU, radiation) treatment was tried, but no effect was demonstrated on follow-up MRI. Then, the change from IMR to CARE (carboplatin and etoposide) treatment brought the decrease of the tumor. Thereafter she has been doing well without neurological deficits for 9 months after the surgery. The strategy of treatment for thalamic gliomas was discussed.

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Differential diagnosis of recurrence or radiation necrosis is sometimes difficult if removal area was enhanced by contrast medium after the multidisplenary therapy of glioma. We experienceed a case of radiation necrosis showing as a recurrence of glioblastoma on imaging and radioisotope scintigram.
The patient was 31 years, female. General convulsion was noted in 1997. Next year, the patient admitted becausee of headache, gait disturbance, and weakness of right hand. Neurologically, right hemiparasis was noted on admission. CT and MRI showed the cystic mass which was enhanced as ring like shape in left frontal lobe. The tumor was totally removed through by right frontal craniotomy and was diagnosed as a glioblastoma. After 50 G ray irradiation, ACNU chemotherapy and IFN immunotherapy were performed, the patient was recovered without neurological deficit. Following the out of patient, right hemiparesis was increased in 2000. Tumor was seemed to be recurred, because Talium scintigram showed hot spot. Second operative specimen was obtained as a radiation necrosis with fibrous tissue and small vascularities.

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