Background Waist circumference (WC) is important as an indicator for obesity and used as diagnostic criteria for metabolic syndrome in Japan. To investigate the difference by the criteria of WC, we compared the relation of WC to cardiac performance in subjects of health screenings.
Methods WC, BMI, blood samples. UCG and BP were measured in 445 men without cardiovascular disease who underwent one night two day health screenings (Ningen Dock). By their WC and BMI, WC85obesity (WC≥85 cm for obesity), WC90 obesity (WC≥90 cm for obesity) and BMI obesity (BMI≥25 for obesity) were defined. After comparing cardiac volume, function and BP between obesity and non-obesity groups, correlation of each parameter to WC and BMI were investigated.
Results Aortic diameter, left atrial dimension (LAD), left ventricular wall thickness, and BP were significantly increased in WC85 obesity. Left ventricular volume and stroke volume were also increased in WC90 obesity. These parameters correlated well with WC, and in multivariable analysis, LAD and posterior wall thickness were the independent predictor for WC. BMI obesity revealed almost same results with WC90 obesity, and LAD and diastolic BP predicted BMI independently.
Conclusions Cardiac volume is increased and hypertrophied in obese men undergoing health screenings. Criteria for obesity changed the relation of cardiac parameters to WC and BMI. WC85 obesity revealed obesity related early cardiac changes and WC90 revealed advanced cardiac changes, almost same with BMI obesity. (Ningen Dock 2009; 23: 29-35)
抄録全体を表示