Official Journal of Japan Society of Ningen Dock
Online ISSN : 2186-5027
Print ISSN : 1880-1021
ISSN-L : 1880-1021
Volume 34, Issue 5
Displaying 1-9 of 9 articles from this issue
Foreword
President Session
Review
Original Articles
  • Yuki Izeri, Takashi Oyama, Ayako Takamori, Junko Miyakawa, Ai Hayashi, ...
    2020 Volume 34 Issue 5 Pages 693-701
    Published: 2020
    Released on J-STAGE: July 01, 2020
    JOURNAL FREE ACCESS

    Objective: The aim of the present study was to examine the influence of Helicobacter pylori (H. pylori) infection on multiphasic health check-up data.

    Methods: Among individuals who received a multiphasic health check-up at Takagi hospital, we included those who underwent a serum anti-H. pylori IgG test. Those who had received H. pylori eradication therapy and had comorbidities were excluded. There were a total of 1,816 subjects in the present study (H. pylori negative: 907, H. pylori positive 909), consisting of 970 men (positive, 51.2%), and 846 women (positive, 48.7%).

    Results: Data were analyzed by the multiple regression technique after adjusting for age. A significant difference between H. pylori negative and positive was observed for the following factors: WBC (p < 0.001, β = 243.84), HDL-C (p = 0.002, β =–2.17), LDL-C (p = 0.003, β = 3.94), platelets (p = 0.007, β =0.62), Hb (p = 0.024, β = –0.16). In men, a significant difference between negative and positive was observed for Hb (p = 0.003, β = –0.2) and in women, there were significant differences for WBC (p < 0.001, β = 372.27), HDL-C (p = 0.002, β = –2.98), Hb (p = 0.014, β = –0.19), platelets (p = 0.015, β = 0.85), and LDL-C (p = 0.028, β = 4.23).

    Conclusion: Blood cell counts and serum lipids were influenced by H. pylori infection, and the effect of H. pylori was more potent in women than in men.

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  • Keiichiro Kondo, Minami Yoshikawa, Naomi Inudou, Ren Fujii, Taisuke Ik ...
    2020 Volume 34 Issue 5 Pages 702-709
    Published: 2020
    Released on J-STAGE: July 01, 2020
    JOURNAL FREE ACCESS

    Objective: To evaluate a relationship between the effect of Specific Health Guidance and change in skeletal muscle volume, we examined the skeletal muscle index (SMI) at the time of the Specific Health Guidance and at the follow-up evaluation for examinees who had metabolic syndrome.

    Methods: Forty-five persons with metabolic syndrome were enrolled in this study. The Specific Health Guidance mainly concerned diet, walking and smoking. The bio-electric impedance method was used to determine the SMI.

    Results: There was no difference in the mean SMI of the 45 subjects between the initial guidance and follow-up evaluation. The changes in SMI were -1.84 ± 2.46% in a reduced SMI group (RG: n=16), -0.38 ± 2.14% in a partially reduced group (PRG: n=22), and 0.76 ± 1.29% in a not-reduced group (NRG: n=7). There was a significant difference in change in SMI between the RG and NRG (p < 0.05). There were positive relationships between percentage change in SMI and change in body weight, percentage change in body weight, and abdominal circumference, respectively (p < 0.05; p < 0.05; p < 0.05).

    Conclusion: In order to maintain skeletal muscle mass, it may be necessary to add resistance training and protein supplementation to regular Specific Health Guidance.

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  • Tatsushi Kitagawa, Kazuma Funahashi
    2020 Volume 34 Issue 5 Pages 710-717
    Published: 2020
    Released on J-STAGE: July 01, 2020
    JOURNAL FREE ACCESS

    Objective: To perform a cross-sectional and longitudinal study on carotid echocardiography (CE) findings.

    Methods: Based on CE evaluations, we divided subjects into three groups: a normal group (A), group with IMC thickening of 1.1 mm or more and plaque formation of less than 20% of carotid artery ratio (CAR) (B), and a group with plaque formation of more than 20% of CAR (C). We determined related factors using multivariate analysis (MA). The changes between past and present CE findings were divided into an improvement group, an unchanged group, and a deterioration group. Differences between the values of the explanatory variables (EV) were calculated and the relationships between them and CE findings were statistically examined.

    Results: MA conducted on two groups, A and B+C, revealed significant differences in age, gender, systolic blood pressure (SBP), HDL-C, and LDL-C, and the standard partial regression coefficient for age was remarkably high. There were no significant differences in MA between the A + B group and the C group except for in age and gender, but fasting plasma glucose tended to be higher in the C group. Examination of changes in CE findings over time and changes in EV using Cox regression showed that increased creatinine (crea) levels and decreased BMI were associated with worsening findings.

    Conclusion: Atherosclerotic findings in CE were greatly affected by aging, and the markers of dyslipidemia and SBP were useful for detecting abnormalities. The results suggested that an increase in plaque was related to impaired glucose tolerance. Deterioration in CE findings over time was associated with an increase in crea levels and a decrease in BMI.

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  • Kenichi Sato, Sorama Aoki, Anna Abe, Akiyo Ozawa, Kenji Hoshi, Junko K ...
    2020 Volume 34 Issue 5 Pages 718-730
    Published: 2020
    Released on J-STAGE: July 01, 2020
    JOURNAL FREE ACCESS

    Objective: Thyroid dysfunction is often overlooked. Therefore, we developed a convenient, low-cost diagnosis support tool for use in screening for thyroid dysfunction using routine test data from health checkups. We have put a screening service (SS) using the tool into practice and report results for its use.

    Methods: For examinees at 3 health check-up facilities, who were recommended to undergo secondary testing due to suspected thyroid dysfunction based on SS results, we measured FT4 and TSH in residual blood. From the hormone measurements, we determined if abnormalities were present and calculated prevalences and positive predictive values (PPVs).

    Results: At the 3 facilities, thyroid dysfunction was discovered in a total of 23 examinees with prevalences of 0.11%, 0.46% and 0.26%, and PPVs of 16.3%, 37.5% and 20.5%, respectively. In the medical examinations by doctors, thyroid dysfunction was only suspected in 2 of the examinees. For thyrotoxicosis, the accuracy of 2-time point prediction greatly exceeded that of single time point prediction, verifying the excellence of time series measurements.

    Conclusion: SS is an effective, new screening method for Graves’ disease and hypothyroidism. Only involving the use of already available routine test data, it is simple and inexpensive to use. It was found to have the advantage of linking examination results in health check-ups with secondary testing by specialists for examinees who may have thyroid dysfunction. Used nationwide, it is expected to lead to the discovery of many patients with thyroid dysfunction who are not aware of any problems.

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  • Hiroyuki Wakamatsu, Hikaru Ohuchi, Shoichi Senda, Yukio Okazaki, Toshi ...
    2020 Volume 34 Issue 5 Pages 731-736
    Published: 2020
    Released on J-STAGE: July 01, 2020
    JOURNAL FREE ACCESS

    Objective: The aim of this study was to examine the usefulness of cardiac auscultation in cardiovascular disease screening.

    Methods: A retrospective study was conducted on findings obtained by screening using electrocardiography (ECG), chest X-rays, or cardiac auscultation in patients newly diagnosed with cardiovascular diseases among 9,763 who had undergone a health check-up at our hospital in the period of one year from April 2018.

    Results: Fifty-two patients were newly diagnosed. Among them, the numbers of findings obtained in screening were 42 for ECG, 23 for cardiac auscultation, and 8 for chest X-rays. Thirty-one of the findings were from a single screening method, consisting of 15 from cardiac auscultation, 16 from ECG, and 0 from chest X-rays. All 15 patients with findings obtained only in auscultation of heart murmurs had valvular diseases, and were asymptomatic in clinical examinations. Four patients who were later diagnosed with moderate or severe valvular diseases had only been positive for cardiovascular disease findings in cardiac auscultation, of whom one underwent valve replacement six months after a health check-up.

    Conclusion: Cardiac auscultation is an essential screening method for valvular diseases.

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  • Michiaki Narushima
    2020 Volume 34 Issue 5 Pages 737-742
    Published: 2020
    Released on J-STAGE: July 01, 2020
    JOURNAL FREE ACCESS

    Objective: We conducted a retrospective observational study of the present status of low-dose CT screening for lung cancer in the Ningen Dock of Showa University Northern Yokohama Hospital.

    Methods: We conducted a retrospective investigation of 1,952 people (1,455 men, 497 women) who received low-dose CT screening for lung cancer in the period from April 2009 to March 2019, mainly on cancer screening quality control index including the secondary testing needed rate.

    Results: The secondary testing needed rate was 3.8% (75/1,952), result confirmation rate was 60.0% (45/75), number of lung cancers discovered was five (including one cancer of unknown origin), and number of lung cancers excised was three. In addition, the rate for receiving secondary testing was 85.3% (64/75), cancer detection rate was 0.20% (4/1,952), and positive-predictive value for secondary testing was 5.3% (4/75).

    Conclusion: Except for the secondary testing needed rate, all rates were higher in comparison with the rates in the national surveillance of lung cancer screening data. In addition, our study demonstrated the usefulness of low-dose CT screening for lung cancer in the Ningen Dock of Showa University Northern Yokohama Hospital.

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