Solitary cutaneous angioleiomyoma with vascular spider which developed on the left cheek of a 21 year-old female was reported. Vascular spider disappeared within two months after the excision of the tumor. Vascular spider and histological feature that epithelioid cells were found around vascular wall of the tumor suggested that this tumor was glomus origin.
A housewife, aged 40, with persistent angiomatous nodules on the ears and scalp is reported. This case agrees with pseudopyogenic granuloma reported by Wilson Jones & Bleehen. Its relationship to subcutaneous angiolymphoid hyperplasia with eosinophilia (Wells & Whimster) and angiolymphoid hyperplasia with eosinophilia (Mehregan & Shapiro) is discussed.
A case of organoid nevus with secondary development of basal cell carcinoma was reported. Histologically, this nevus had small areas of basaloid cell proliferation. It was suggested that the area of basaloid cell proliferation might be an early lesion of basal cell carcinoma. In addition, cystic dilatation of sweat glands was found in the same specimen. It was revealed by the examination of serial sections that cystic dilated sweat glands were eccrine and apocrine glands. The cystic dilatation might be due to retention of sweat caused by obstruction of sweat ducts.
Three cases of Kasabach-Merritt syndrome, 4 and 2 months and 16 days of age, were successfully treated with Liniac electron beam irradiation for each hemangioma lesions by the total dosis of 1800, 900 and 2400 rads. The irradiations were discontinued before the complete flattening of hemangiomas, and after that the spontaneous regression of hemangiomas and the reduction of platelet counts in peripheral blood were observed. The irradiation technique in the treatment of Kasabach-Merritt syndrome using minimal dosis of electron beam were discussed.
The activity levels of thymidine kinase and 5′-nucleotidase for dTMP were investigated by measuring enzyme activities in normal skin and tumors of the skin. In rat's normal skin, the activity of thymidine kinase was much higher than in rat's normal liver. The activity of 5′-nucleotidase for dTMP in rat's normal skin was similar to that of rat's normal liver. A reciprocal relationship was found between the activity of thymidine kinase and that of 5′-nucleotidase for dTMP during the induction of epidermal neoplasms in mice by topical methylcholanthrene. A reciprocal relationship between thymidine kinase and 5′-nucleotidase for dTMP was found in human normal skin and tumors of the skin.