As discussed in a previous report, the results of an open study of L-DOPA for alopecia areata suggested to be a helpful regimen for alopecia areata. This time, a comparative test by double blind study was carried out between L-DOPA with corticoid and lactose (placebo) with corticoid, but L-DOPA did not reveal an effect on alopecia areata as corticoid had a strong effect on the hair follicle. Maintenance of growing hair by the use of L-DOPA was not apparent, as the hair falling was recognized after the discontinuance of corticoid therapy in both groups. Comparing the effect between a group of patient given L-DOPA and a group of no therapy at monthly intervals, the former group improved of better than the latter. Though a slight side effect was encountered, this L-DOPA therapy could be continued by most of patients.
Nineteen patients with psoriasis vulgaris underwent the 8 MOP-BLB therapy combined with steroid ODT. 1. Twenty-six psoriatic lesions were improved after one to seven exposures (average time is 3.8 exposures). Seventeen psoriatic lesions were completely healed after three to thirteen exposures (average time is 9.9 exposures). 2. After psoriatic lesions were moderately improved by only steroid ODT, the 8 MOP-BLB therapy combined with steroid ODT was attempted. Seventeen psoriatic lesions were improved after two to three exposures (average time is 2.5 exposures). Eleven psoriatic lesions were completely healed after five to ten exposures (average time is 7.3 exposures). 3. Relapses of the lesions which had completely healed have not been observed until at this moment for three months.