The author introduces to the basic facts and of brief histories of the perfect state of the dermatophytes. The classification of Trichophyton mentagrophytes, prior to the discovery of its perfect states, is reviewed. On the basis of the perfect states obtained by confrontations of strains of T. mentagrophytes, it is demonstrated that it is minimum of a complex of different asexual strains corresponding to three perfect states : Arthroderma simii, Arthroderma benhamiae and Arthroderma vanbreuseghemii. On the basis of their mating behaviour, their morphology in culture and/or their biochemical characters, the members of the T. mentagrophytes complex can also be divided in races, varieties and conidial forms. Though Trichophyton interdigitale is a member of the T. mentagrophytes complex, its exact status remains unknown so far.
The author reported several morbid anatomical findings of deep fungus infections, especially on candidiasis, aspergillosis, mucormycosis, and cryptococcosis. Special stress was layed on cryptococcosis, and described the followings: 1) The degree of size variation and the occurrence of aberrant forms of Cryptococcus cells could be assumed as a reliable clue for the determination of the stage of the infection. 2) Morphological peculiarity of the multinucleated giant cells in the granulomatous lesion was pointed out. 3) Fluorescence microspectrophotometry could be assumed as a reliable tool not only for the evaluation of the viability of the fungus in tissue, but also for the evaluation of antifungal drugs.