The Nishinihon Journal of Dermatology
Online ISSN : 1880-4047
Print ISSN : 0386-9784
ISSN-L : 0386-9784
Volume 41, Issue 5
Displaying 1-27 of 27 articles from this issue
Color Atlas
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Clinical Case Reports
  • Keijiro KITAMURA, Tami IMAI, Seiichi KURIHARA, Hitoshi HATANO, Ryuichi ...
    1979 Volume 41 Issue 5 Pages 856-863
    Published: October 01, 1979
    Released on J-STAGE: March 22, 2012
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    A 32-year-old female patient with a glycogen storage disease (von Gierke’s disease) having multiple subcutaneous nodules was reported. She was small in stature with a doll-like appearance on her face, having hepatosplenomegaly and a bleeding tendency. The cutaneous manifestations were multiple, slightly yellowish subcutaneous nodules on her buttocks, thighs and knee joints. Laboratory studies disclosed the following values: fasting blood sugar: 38mg/dl; serum uric acid: 12.1mg/dl; serum lactate: 115mg/dl; serum cholesterol: 320mg/dl; serum phospholipid: 634mg/dl; and serum triglyceride: 1072mg/dl. Based on these data together with the results of oral-GTT, glucagon tolerance test and enzymologic examinations of blood cells, this patient was diagnosed as suffering from von Gierke’s disease. Histopathologically, she had an enlarged fatty liver, whose cells contained a large amount of glycogen granules. The subcutaneous nodule was a foreign body granuloma including white chalky glutinous materials, which consisted of uric acid, phospholipid, triglyceride and cholesterol-ester histochemically. This is believed to be a case of von Gierke’s disease with tophaceous gout.
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  • Koji MATSUDA, Tomoyuki KAWATSU, Yoshiharu MIKI
    1979 Volume 41 Issue 5 Pages 864-871
    Published: October 01, 1979
    Released on J-STAGE: March 22, 2012
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    Multiple, recurrent red papulovesicular eruptions leaving depressed scars in the face, dorsa of hands and lower legs of 1 to 2 years’ duration were observed in two 5-year old boys and in a 12-year old girl. Conjunctival hyperemia and corneal opacity were observed in the boy patients. Histologically, intra- and sub-epidermal bullae and superficial dermal necrosis were observed. Blood, urinary and fecal porphyrins were within normal limits. Serum iron was decreased in all 3 patients. Urinary amino acids were slightly increased in the girl patient. UVB minimal erythema dosis was 3 minutes in each patient. Photo-provocation could not be induced clinically in the range of UVB (305±5nm, 0.675J/cm2), UVA (352±5nm, 4.39J/cm2), UVA and UVB, visible (420±5nm, 4.32J/cm2 or 525±5nm, 7.9J/cm2), infra-red (a 800 Watt heater) or solar (110 minutes) lights. Nineteen patients without the evidences of porphyria as shown in the Japanese literature were reviewed.
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  • Kenichiro INOKUCHI, Hiroshi HACHISUKA, Hikaru TANAKA
    1979 Volume 41 Issue 5 Pages 872-875
    Published: October 01, 1979
    Released on J-STAGE: March 22, 2012
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    A case of naevus sebaceus associated with basal cell epithelioma and hidradenoma was reported. Some literatures with regard to naevus sebaceus with secondary tumors were reviwed.
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  • Yasuyuki SHIMIZU, Shuhei SHIMAO, Hiroyuki OHNO
    1979 Volume 41 Issue 5 Pages 876-879
    Published: October 01, 1979
    Released on J-STAGE: March 22, 2012
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    A 42-year-old man who had syringocystadenoma papilliferum with basal cell epithelioma on the left inner eye angle and with nevus sebaceus on the top of the scalp was reported. We suspected that histogenesis of this syringocystadenoma papilliferum was based on disorders of the development of embryonal stratum germinativum.
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  • Katsutaro NISHIMOTO, Toshikazu NISHI, Hidekazu SHINODA
    1979 Volume 41 Issue 5 Pages 880-882
    Published: October 01, 1979
    Released on J-STAGE: March 22, 2012
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    An 88 year-old female visited the Dermatology Clinic, Shimabara Hospital, Nagasaki, for ulcerative lesions on her right forearm and elbow. Histological examination revealed foreign-body granuloma with round fungus cells in them and Sporothrix schenckii was isolated. Lesions were treated once a day with medical heating sheet “Erhitzen”, which kept the topical temperature at 45°C for 3 hours. After one week ulcers began to regress and completely healed within 50 days.
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  • Takashi NAGATA, Yutaka MIYAMOTO, Tomomichi ONO
    1979 Volume 41 Issue 5 Pages 883-886
    Published: October 01, 1979
    Released on J-STAGE: March 22, 2012
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    A case of kerion celsi in a female infant was initiated about 20 days after her birth. Trichophyton rubrum was cultured from the involved hairs of the patient. In the literature the most common causative organisms of kerion celsi had been formerly T. ferrugineum and T. mentagrophytes, but recently Microsporum canis, M. gypseum and T. rubrum have become major pathogens of the disease.
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  • Naoto KANBE, Miki ASO, Shuhei SHIMAO
    1979 Volume 41 Issue 5 Pages 887-890
    Published: October 01, 1979
    Released on J-STAGE: March 22, 2012
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    Two cases of prurigo pigmentosa were reported. Clinical findings of both cases were almost compatible with those of Nagashima’s original description. But the first case showed vesicles based on eosinophilic degeneration or necrosis of keratinocyte and the biopsy specimen of pigmented area revealed papillomatosis.
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Clinical and Investigative Report
  • Toshihisa NOZAKI
    1979 Volume 41 Issue 5 Pages 891-897
    Published: October 01, 1979
    Released on J-STAGE: March 22, 2012
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    In halo neves, the central mole was gradually seen fading without repigmentation after being removed and brought back to its original place. However, when 8-MOP was administrated and solar irradiation was performed after the same treatment, no repigmentation from the mole was observed. In some cases, moles decreased in size from the margin of the halo. When a healthy skin graft was transplanted to the halo, and while the mole was left alone, repigmentation was seen in the halo region. But repigmentation was observed soon after the central mole was replaced with a healthy skin graft. A healthy skin graft was transplanted to the halo region when the central mole was left alone. After 4 years and a half, the central mole faded. At this time, the central mole was removed and examined histologically. Nevus cell nests were noted in corium and a few melanin were left in superficial layer. No other particular findings were observed. On the other hand cellular invasion was not seen in the circumference of the nevus cell nest, a process of destruction was observed in the central part of the nevus.
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  • Noriya KUBO
    1979 Volume 41 Issue 5 Pages 898-905
    Published: October 01, 1979
    Released on J-STAGE: March 22, 2012
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    By a precipitation test using the culture filtrate of Sporothrix schenckii as antigen, the followings were investigated: 1) detection of blood antibody in patients with sporotrichosis and variation of antibody according to the activity of the disease, and 2) antigen titers associated with culture duration as well as the effect of heating on the antigenicity. The results were as follows:
    1) Positive results were obtained in 22 of 23 patients with sporotrichosis and in 28 of 836 controls. Serologically, the reaction was generally “labile” in the fixed type of the disease and “stable” in the lymphatic type, however the clinical symptoms did not always parallel the antigen titers.
    2) In a week culture filtrate of S. schenckii, the antigenicity was not observed and the strength of the reaction was found in the order of weeks 5≤9≤13≤17≤14. No decrease in reaction was noted even after heating the antigen. This shows that this antigen may be thermostable. Sporotrichin skin test was positive in all cases. In the precipitation test for sporotrichosis, the fixed type tended to be more reactive than the lymphatic type, however there was no difference in positive rate between both types. In experiments with rabbits immunized with heat-killed S. schenckii, the reaction continued to be positive for a period up to one year and a half after completion of the immunization.
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  • Tetsuro SUGAI, Takashi TAKAGI, Yohko TAKAHASHI, Ritsuko HAYAKAWA, Mie ...
    1979 Volume 41 Issue 5 Pages 906-920
    Published: October 01, 1979
    Released on J-STAGE: March 22, 2012
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    A new series of hypo-allergenic cosmetics “CLINICA” without any fragrant materials was evaluated in 176 female patients who visited the dermatologic clinics at Branch Hospital of Nagoya University, Kansai Medical University and Osaka Kaisei Hospital. The patients were divided into three groups: 72 patients with non-pigmented cosmetic dermatitis, 64 with pigmented cosmetic dermatitis and 40 with other dermatosis than cosmetic dermatitis, such as melasma. In patch-testing with 30 “CLINICA” products, it was found that the skin irritant index of each product was lower than the average index of the commercial preparation. In addition, neither phototoxic nor photoallergic reaction was detected in “CLINICA” products. Thus, “CLINICA” has been evaluated to be hypo-irritant cosmetics. The use test with “CLINICA” was performed in 150 out of 176 patients. A single product was applied every two weeks continuously. Skin troubles occurred in 20 patients (13.3%), and in 52 out of the whole 1,727 cases with 29 test products (3.0%). The second use test was carried out in 8 out of the 20 patients 3 to 6 months later. Skin troubles occurred again in 5 out of the 8 patients (62.5%), and in 5 out of 17 products tested (29.4%). The allergenic ingredients of “CLINICA” are parabens in the whole products except for the cosmetic solution, and a few kinds of coal-tar dyes in some make-up products. It is recommended, thus, to be patch-tested with the allergens equipped in “CLINICA” series before the use test.
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