The Nishinihon Journal of Dermatology
Online ISSN : 1880-4047
Print ISSN : 0386-9784
ISSN-L : 0386-9784
Volume 45, Issue 3
Displaying 1-25 of 25 articles from this issue
Color Atlas
Mini Review
Clinical Case Reports
  • Kimihiko MIHARA, Masayuki NISHIMURA, Yuwao HINO, Hiromu KOHDA
    1983 Volume 45 Issue 3 Pages 360-364
    Published: June 01, 1983
    Released on J-STAGE: March 21, 2012
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    We report a 56-year-old Japanese man who developed over two hundred asymptomatic blue-black papules disseminated mainly on the forehead and both cheeks. Except for the unusual anatomical location, the clinical appearance and histological features were in accord with those of eruptive vellus hair cysts and we diagnosed this case as one of eruptive vellus hair cysts of the face. To our knowledge, this is the third such case reported in the literature.
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  • —Dowling Meara’s Type?—
    Michi MIZUGUCHI, Kayoko KANEKO, Michiko KAWAKAMI
    1983 Volume 45 Issue 3 Pages 365-371
    Published: June 01, 1983
    Released on J-STAGE: March 21, 2012
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    A 30-year-old man had blisters which repeatedly appeared on the trunk and extremities, from the third postnatal day. The blisters from 0.3 to 1cm in diameter were partially distributed in a circinate fashion. He also presented linear or reticular pigmentation on the trunk and extremities, severe itching, nail dystrophy, as well as palmo-plantar hyperidrosis and hyperkeratosis, but neither milia nor scar was observed. The blisters, looking subepidermal proved to be intraepidermal by electron-microscopic examination: the basal cells revealed segregation of cytoplasmic constituents and tonofibrillar clumping, followed by cytolysis. Although the family history suggested a recessive trait (no affected members in the family, and the parents are first cousins once removed), this case probably can be considered as belonging to Dowling-Meara’s type of dominant epidermolysis bullosa hereditaria.
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  • —Simultaneous Occurrence of Amyloid Deposition—
    Naohide TAKEHARA, Hidetoshi NAKAYAMA, Motoyuki MIHARA, Shuhei SHIMAO, ...
    1983 Volume 45 Issue 3 Pages 372-376
    Published: June 01, 1983
    Released on J-STAGE: March 21, 2012
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    A 45-year-old man had a generalized pigmentary disorder with the onset at about age 12. In the family history a sister, 50 years old, had a similar skin pigmentary defect with the onset at a similar age. The histological features resembled those of xeroderma pigmentosum with an atrophy in the depigmented area and elongation of the epidermal rete ridges in the pigmented area. Ultrastructurally, ultrathin sections from the pigmented area showed melanin-pigment-accumulated keratinocytes with signs of degeneration. On the contrary, those from the depigmented area showed not such cells but rather vacuolated keratinocytes or keratinocytes with an electron lucent substance in the perinuclear area. In all the ultrathin sections, the melanocytes appeared almost normal. Occasional occurrence of amyloid deposition in close contact with the degenerated basal cells was suggestive of a keratinocyte origin. Therefore this pigmentary disorder may relate to abnormal conditions in pigment transfer, as the result of keratinocyte degeneration, and here hereditary factors may play an important role.
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  • Yoshihiro MAEKAWA, Yoshikado SAKAZAKI, Koichiro MUTO, Reiko NOGAMI, Hi ...
    1983 Volume 45 Issue 3 Pages 377-382
    Published: June 01, 1983
    Released on J-STAGE: March 21, 2012
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    A 41-year-old Japanese woman, who noticed a struma and glycosuria 3 years ago, had Raynaud′s phenomenon and a sclerodactylia over fingers and forearm. She was admitted for evaluation of the spread of the sclerosis over the entire skin area. She was diagnosed clinical as a case of progressive systemic sclerosis (PSS) as there were flexion contracture, ulcer and sclerosis on the fingers, a mask-like appearance, protruding of her lips without a nasolabial fold. Laboratory findings revealed diabetes mellitus following examination of 50g GTT, and Hashimoto’s thyroiditis as the result of T3, T4 and TSH examination and Tc scintigram. Glycosaminoglycans in the urine were increasingly excreted, as compared to the normal controls. PCPG-AAN and PLP applications improved slightly the sclerosis on the forearms, but had no effect on the disturbances in breathing. There are some cases of PSS with Hashimoto’s thyroiditis in the literature. The possible pathogenesis of PSS was discussed from the standpoint of immunologically-related disorders.
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  • Shigeo NONAKA, Taro OHGAMI, Kazunori YOSHIDA, Kazuya EGAMI, Michitami ...
    1983 Volume 45 Issue 3 Pages 383-392
    Published: June 01, 1983
    Released on J-STAGE: March 21, 2012
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    Five cases of porphyria cutanea tarda with mild cutaneous changes are reported. Hyperpigmentation and small scars on the exposed areas were the most significant cutaneous changes. Acute episodes of photosensitivity were nil. All patients admitted to a long history of excessive alcohol intake. The abnormality of the liver function tests was determined by another physician before the first examination in our clinic. The laboratory examinations showed a predominance of uroporphyrin in the urine in 4 of 5 cases. In one patient, there was a relatively low urinary porphyrin level, despite an abnormal porphyrin pattern. In four there was a predominance of uroporphyrin in the urine as well as a high level of serum coproporphyrin. Histopathologically, all had a deposition of PAS positive materials surrounding the small blood vessels in the upper dermis, in addition to the deposition of IgG materials determined using immunofluorescence. The diagnosis of porphyria cutanea tarda cannot be accurately made on the histopathological and laboratory findings only. Furthermore, some caution is needed for a diagnosis of this disease because of slight cutaneous changes in recent cases. A phlebotomy was performed in one patient. The urinary porphyrin level gradually reverted to normal and we determined that the urinary porphyrin pattern shifted from uroporphyrin and hepta-carboxyl porphyrin predominance to coproporphyrin predominance. We therefore speculate that a phlebotomy normalizes the uroporphyrinogen decarboxylase activity. Although the mechanism of action of the phlebotomy is unknown, an analysis of the urinary porphyrin profile is a useful laboratory tool for the diagnosis or for the progress of the course of porphyria cutanea tarda, as well as for a quantitative analysis of urinary porphyrins.
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  • Kiyoshi NAKAYASU, KAZUO KOBAYASHI, Shunji WAKABAYASHI, Junko HORIE
    1983 Volume 45 Issue 3 Pages 393-396
    Published: June 01, 1983
    Released on J-STAGE: March 21, 2012
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    We treated chondrodermatitis nodularis chronica helicis in a 56-year-old man. Clinically the patient had a cartilaginous hard, superficial, brownish, dome-shaped nodule with a small central depression, 8mm in diameter and about 2mm thick, on the helix of the right ear. Histologically, nodular acanthosis with a central depression capped by a hyper- and parakeratotic scale, fibrinoid degeneration of dermal collagen with formation of a subepidermal cyst, a vascularized granulation tissue surrounding the degenerated collagen and perichondritis with cartilaginous degeneration were identified. The degenerated materials showed a transepidermal elimination.
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  • Hiroaki NAGANO, Koichiro MUTO, Masayoshi JOHNO, Tatsuyoshi ARAO
    1983 Volume 45 Issue 3 Pages 397-402
    Published: June 01, 1983
    Released on J-STAGE: March 21, 2012
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    A 40-year-old man, who had been burned at age 5 years, had a squamous cell carcinoma on the right popliteal region associated with metastasis to the femoral lymphnodes. Widespread hematogeneous metastasis became evident soon after excision of the carcinomatous tissues. A marked hypercalcemia and granulocytosis appeared at the end stage. An excess secreting parathyroid hormone (PTH) or colony stimulating factor (CSF) from the tumor cell was considered, but there was no evidence of high levels of PTH or CSF in the blood and urine. Surgery and radio- and immunotherapy proved to be ineffective and he died about 10 months after onset of the disease.
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Clinical and Investigative Report
  • Hisaya TSUGAMI
    1983 Volume 45 Issue 3 Pages 403-407
    Published: June 01, 1983
    Released on J-STAGE: March 21, 2012
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    A new isolation medium for dermatophytes, composed of 10g of phyton pepton, 20g of glucose, 10g of agar, 0.5g of 5-fluorocytocine, 80mg of gentamicin sulfate and 1 liter of distilled water, was clinically tested. In a series of cultures of skin scales, dermatophyte isolates obtained from 365 out of 473 patients were tested. There were also 74 cases of no growth and 24 and 10 cases of saprophytic fungal and bacterial contaminations, respectively. The new medium resulted in a more satistactory isolation rate and more rapid growth of dermatophytes than did Sabouraud dextrose agar and the chromo-production of Trichophyton rubrum in the former medium was more rapid than that in the dextrose agar.
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  • Atsushi SUZUKI, Yuko SONODA, Toshifumi NISHIMOTO, Seiichiro SAGAMI
    1983 Volume 45 Issue 3 Pages 408-410
    Published: June 01, 1983
    Released on J-STAGE: March 21, 2012
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    We reviewed the effect of topical application of corticosteroid both in cream and ointment form (halcinonide cream, ointment). Such was applied in cases of erythema induced in human volunteers by 1.5 MED ultraviolet rays.
    1) The halcinonide cream had a more rapid effect than the ointment, however, the former caused a characteristic change of the skin i. e., crepe-like appearance of the skin.
    2) In general, the efficacy of halcinonide ointment was better than that of halcinonide cream and in the depot effect of the corticosteroid, the ointment was superior to the cream.
    3) The corticosteroid effects of every two hours’ application and that of every four hours’ application were much the same and every eight hours’ application was less effective.
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  • Tsuneo OHSHIMA, Keiko OHSHIMA
    1983 Volume 45 Issue 3 Pages 411-416
    Published: June 01, 1983
    Released on J-STAGE: March 21, 2012
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    In Japan the number of elderly persons complaining of pruritus increases in fall and winter, dry seasons, in the country. This symptom which is known as “pruritus senilis” has been regarded as a form of xeroderma. However, various diseases are falsely considered as pruritus by the elderly. Therefore, in the treatment of such cases, lesions which cannot be detected as a result of the diminished sensitivity in the elderly should be confirmed by careful evaluation. Described herein are experiences of successful treatment of such pruritus by psychotherapy alone and no drugs, for those not regarded as having xeroderma, as a rich sebum was apparent as was the use of an emollient cream and cosmetics.
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