The Nishinihon Journal of Dermatology
Online ISSN : 1880-4047
Print ISSN : 0386-9784
ISSN-L : 0386-9784
Volume 50, Issue 6
Displaying 1-22 of 22 articles from this issue
Color Atlas
Mini Review
Clinical Case Reports
  • A Case Report
    Nobuaki TAKE, Tetsuya HIRANO, Osamu IYOTA, Yoshinori SUENAGA
    1988 Volume 50 Issue 6 Pages 1018-1021
    Published: December 01, 1988
    Released on J-STAGE: March 07, 2012
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    The case of a patient with psoriasis vulgaris who afterwards developed bullous pemphigoid is reported. The patient was a 66-year-old female, who had been treated for about ten years for psoriasis vulgaris skin eruptions. Recently, “Simfibrate”, an antilipemic drug, was administered for her hypertension and two months later, bullous lesions developed all over her body. A biopsy examination revealed subepidermal bulla formation and dermal infiltration of lymphocytes. Direct immunofluorescent staining showed linear C3 deposits at the basement membrane zone. The serum anti-basement membrane IgG antibody was also detected with the titer of 40 fold.
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  • A Case Report
    Noriyuki MISAGO, Hiromu KOHDA
    1988 Volume 50 Issue 6 Pages 1022-1026
    Published: December 01, 1988
    Released on J-STAGE: March 07, 2012
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    We reported the case of a 72-year-old man with erythroderma-like psoriasis provoked by group D streptococcal pyothorax. We first treated him for pyothorax using antibiotics and thoracic drainage without treatment for psoriasis. Then, as the pyothorax improved, the scaled erythema over his entire body also cleared. Thereafter, psoriasis vulgaris lesions reappeared on his elbow joints. We discussed the role of infection in the enhancement or development of psoriasis in this case.
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  • Haruhisa KATO, Toshio HAMADA
    1988 Volume 50 Issue 6 Pages 1027-1030
    Published: December 01, 1988
    Released on J-STAGE: March 07, 2012
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    A case of multiple apocrine hidrocystomas is reported. A 63-year-old female had two soft cystic structures on the right upper eyelid and left outer canthus of 3 months’ duration. The tumors were 0.3×0.3 cm and 0.7×0.7 cm, respectively, slightly elevated or dome-shaped, and translucent. Histopathological examinations revealed cystic structures that largely consisted of single or multiple layers of secretory epithelium, showing decapitation secretion. One of them, which occurred on the right upper eyelid, showed a connection with the infundibulum of a hair follicle, and papillary projection of the cystlining into the cavity. PAS-positive, diastase-resistant secretory granules were found in the secretory cells. The other, which occurred on the left outer canthus, consisted of a cystic cavity whose wall was lined by a single layer of epithelial cells, showing no decapitation secretion. A few PAS-positive secretory granules were demonstrated. There were no myoepithelial cells at the periphery of the secretory cells in either case. This is the third case of multiple apocrine hidrocystomas to appear in the Japanese publications.
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  • A Cutaneous Horn-like Tumor
    Setsuko TSUDA, Noriyuki MISAGO, Yutaka NARISAWA
    1988 Volume 50 Issue 6 Pages 1031-1034
    Published: December 01, 1988
    Released on J-STAGE: March 07, 2012
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    We report an ususual case of a 75-year-old woman who had a cutaneous horn-like keratinized tumor on her left nipple. A biopsy specimen distinctly revealed Paget’s disease of the breast. Histopathologic examination showed marked hyperkeratosis, numerous Paget cells lying singly and in groups in the dermis and so-called comedo carcinoma in the dermis that stained strongly positive with CEA.
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  • A Report of 2 Cases
    Mariko YAMAMOTO
    1988 Volume 50 Issue 6 Pages 1035-1038
    Published: December 01, 1988
    Released on J-STAGE: March 07, 2012
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    Seven cases of Bowen’s disease were histochemically studied (HE, PAS, Congo red and Dylon stainings). Papillary and subepidermal deposits of amyloid were found in two patients. Immunohistological studies were carried out in the two cases with amyloid deposits by the PAP method using antikeratin antibodies. The reactions remained negative, while the epidermal keratinocyte showed positive reactions.
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  • A Report of 2 cases
    Shunji NAKANO, Hiroshi HACHISUKA, Hidemasa KAJI, Yoichiro SASAI, Koji ...
    1988 Volume 50 Issue 6 Pages 1039-1044
    Published: December 01, 1988
    Released on J-STAGE: March 07, 2012
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    Two cases of cutaneous malignant hemangioendothelioma which occurred following radiotherapy at the site of the buttock and appeared idiopathically on the scalp are reported. Case 1: 78-year-old female developed erythema and ulcers 25 years after in radiation for of malignant hemangioendothelioma carcinoma uteri. The tumor was removed and a skin graft was performed at the buttock. Local recurrences appeared over the next 3 years. She died 6 years after the initial appearance because of hemothorax. Case 2: 58-year-old male had noted a firm reddish tumor at the frontal region, which subsequently increased in size. The tumor was removed surgically. Fifteen months after the initial appearance, he died due to lung metastasis. Histological examination evaluated cases 1 and 2 respectively as moderate to poorly differentiated and well differentiated malignant hemangioendothelioma.
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Clinical and Investigative Report
  • Mamoru KASADA
    1988 Volume 50 Issue 6 Pages 1045-1049
    Published: December 01, 1988
    Released on J-STAGE: March 07, 2012
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    The nature of collagen and acid mucopolysaccharides in six fibrous skin tumors (fibroma, dermatofibroma, schwannoma, neuro-fibroma, dermatofibrosarcoma protuberans and leiomyoma) was studied by optical and electron microscopy. Abundant collagen fibrils were present in all these tumors, except for leiomyoma. Fibroma and dermatofibroma were shown to be formed by thick collagen fibrils with strong birefringent fibers and the presence of dermatan sulfate. Schwannoma and neurofibroma presented thin collagen fibrils with weak birefringence and hyaluronic acid, while dermatofibrosarcoma protuberans contained nonpolarizable collagen. These results suggest that there were two types of collagen fibers in the tumors studied, and that collagen fibril diameters are related to the acid mucopolysaccharide type.
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  • Masami YOSHIDA, Tadashi TEZUKA
    1988 Volume 50 Issue 6 Pages 1050-1054
    Published: December 01, 1988
    Released on J-STAGE: March 07, 2012
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    Five cases with cutaneous herpes simplex suspected of being transmitted via household appliances or medical appliances are reported. To study the possibility of virus transmission by such appliances, we periodically performed virus isolation from appliance materials on which virus solution had been painted or dripped. It was found that the virus could be isolated from all materials until 1 hour later. This result suggests that these appliances can convey the herpes simplex virus,
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  • —Using Rabbits with Oral Administration of AgNO3
    Yuhei TADA, Shin-ya TAKAHASHI
    1988 Volume 50 Issue 6 Pages 1055-1059
    Published: December 01, 1988
    Released on J-STAGE: March 07, 2012
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    Olive oil suspension containing 0.2g of AgNO3 was administered orally once daily to 9 rabbits who were divided into 2 groups consisting of 6 and 3 rabbits, with or without irradiation of fluorescent light, respectively. To the 3rd group comprising 3 rabbits, a control group, only olive oil was administered in the same manner. Macroscopically, microscopically and quantitatively, a comparative study on the differences of hyperpigmentation as well as deposition of silver particles in the skin and viscera of these 3 groups was performed at 40, 70 and 125 days after oral administration of AgNO3. The results were as follows;
    1) In the skin, no hyperpigmentation was observed clinically in the 3 groups at any times, but silver particles were found very sparely in the basement zone of the follicles, and 2 to 5 ppm of silver was detected after administration of 14 g and 25 g of AgNO3.
    2) In the intestines, very slight pigmentation was noted after administration of 14 g 25 g of AgNO3, and only about the same amount as in the skin was obtained.
    3) In the kidney and the liver, an apparent hyperpigmentation was seen even when 8 g of AgNO3 had been administered, and it became more intense with the increase of total dose. Deposition of silver particles in the kidney was detected in greater amounts from the medulla (162.5 ppm) than from the cortex (32.6 ppm) after administration of 25 g AgNO3.
    The reason why rabbit skin did not exhibit any apparent hyperpigmentation may be due to the lack of eccrine as well as sebaceous glands which are an external secretory gland. In conclusion, the bluish gray pigmentation in generalized argyria can be principally attributed to deposits of silver particles.
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  • —Histological Examination of Polysacchardeis in the Healing Process—
    Tomohide AKIBA, Yoshinori ETO, Yasushi WADA, Masayoshi TAKIMOTO, Masan ...
    1988 Volume 50 Issue 6 Pages 1060-1068
    Published: December 01, 1988
    Released on J-STAGE: March 07, 2012
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    The effects of a topically applied 70% sucrose solution on the wound healing process were investigated in open wounds induced by trepanation on the rat dorsal skin. As indices of wound healing, glycogen and hyaluronic acid contents were estimated histologically in regenerated epidermis and in wounded dermis, respectively. In a control group, distilled water was applied instead of the 70% sucrose solution. After skin trepanation, the glycogen content gradually increased in the regenerated epidermis and reached the maximum level 4 days after skin trepanation in the control group, and at this time, in the sucrose treated-group, a larger increase in the glycogen content was observed than in the control group. The increases in glycogen content were fairly well correlated to the number of mitotic cells counted in the regenerated epidermis. In regard to the wounded dermis, hyaluronic acid content was increased from day 1 through day 3 after skin trepanation, then gradually decreased and, on the 6th day after skin trepanation, it reached almost the same level as that observed on day 1 after skin trepanation in the control group. In the sucrose treated-group, hyaluronic acid content was somewhat higher until the 3rd day after trepanation, and afterwards became lower than in the control group. These results suggest the accelerating effects of sucrose on the healing process of experimentally induced open wounds.
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  • Ken NOMA, Nobuyuki SHIMIZU, Akira YAMADA, Taizo TANIZAKI, Hiromu YOSHI ...
    1988 Volume 50 Issue 6 Pages 1069-1077
    Published: December 01, 1988
    Released on J-STAGE: March 07, 2012
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    Open treatment on the face consists of a circular excision of the tumor leaving the wound open and allowing it to granulate spontaneously. This non-suture technique is most simple and effective. However, this technique can only be applied to a defect which is less than 7 mm in diameter. We can diminish the size of circular wounds of more than 7 mm in diameter by applying purse string suture and allow them to heal by spontaneous granulation. We could achieve good results by this procedure under the following conditions: 1. the patient was over 60 years old with a defect of less than 20 mm in diameter. 2. the patient was under 30 years old with a defect of less than 10 mm in diameter.
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Review
Statistics
  • Yumi SASAJIMA, Hajime IIZUKA
    1988 Volume 50 Issue 6 Pages 1085-1090
    Published: December 01, 1988
    Released on J-STAGE: March 07, 2012
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    Statistical analysis was made on skin diseases of children. The subjects consisted of nine hundred and fifty-eight children aged under fifteen years old who visited the outpatient dermatology clinic of Asahikawa medical college in 1986 and 1987. The results were as follows:
    1) Percentage of children was about 27% of all the new outpatients.
    2) About 44% of them were primary school children and junior high school students. Percentages of children aged from 1 year to 5 years and those of less than 1 year old were 38% and 18% respectively.
    3) The children visited the outpatient clinic most frequently in January, March and August, which corresponds with school vacations.
    4) Eczema-dermatitis, including atopic dermatitis, was most frequently seen in the children and the percentage was more than 50%.
    5) Children aged from 1 year to 5 years and primary school children had more viral and bacterial skin diseases than other children under 1 year old or junior high school students. The most common of these infectious skin diseases were verruca vulgaris, molluscum contagiosum and impetigo contagiosa.
    6) More than 80% of the skin diseases of children were non-infections diseases.
    7) Non-infectious as well as infectious skin diseases should be checked in a dermatological health examination by a dermatologist at schools.
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  • Takeshi IMAFUKU
    1988 Volume 50 Issue 6 Pages 1091-1095
    Published: December 01, 1988
    Released on J-STAGE: March 07, 2012
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    The incidence of dermatophytoses and dermatophytes in the Imafuku Dermatology Clinic in Nagasaki between 1985 and 1986 was studied. A total of 1,185 patients with dermatophytoses, 10.1% of all the outpatients, was observed. There were 884 patients with tinea pedis, 147 with T. corporis, 78 with T. cruris, 35 with T. unguium and 6 with T. capitis. The species most frequently isolated was T. rubrum (426 strains, 58.2%), followed by T. mentagrophytes (279 strains, 38.1%), M. canis (20 strains, 2.7%), E. floccosum, (4 strains), T. glabrum (2 strains) and 1 strain of T. violaceum. The ratio of T. rubrum to T. mentagrophytes was 1.53 (426/279) in all the tinea patients and 0.93 in the tinea pedis patients.
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  • Yohinobu KIRIHARA, Osamu YAMAMOTO, Akio HORIE, Masakazu ASAHI
    1988 Volume 50 Issue 6 Pages 1096-1099
    Published: December 01, 1988
    Released on J-STAGE: March 07, 2012
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    Ninety cases of basal cell epithelioma treated at the Hospital of the University of Occupational and Environmental Health between 1979 and 1988 were analyzed, mainly histopathologically. Firstly, the distributions of sex, age and region were analyzed. Next, several histopathological features, such as histological types, tumor cell shapes, palisading arrangement, pigmentation and the existence of psammoma body, were studied in relation to the patient’s age and tumor localization.
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