The Nishinihon Journal of Dermatology
Online ISSN : 1880-4047
Print ISSN : 0386-9784
ISSN-L : 0386-9784
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Volume 57, Issue 6
Displaying 1-21 of 21 articles from this issue
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Clinical Case Reports
  • Reiter’s Disease in HTLV-1 Carrier Successfully Treated with Cyclosporin
    Ken MIYOSHI, Kouzou OKAWA, Hajime KODAMA
    1995 Volume 57 Issue 6 Pages 1132-1136
    Published: December 01, 1995
    Released on J-STAGE: July 20, 2011
    DOIhttps://doi.org/10.2336/nishinihonhifu.57.1132
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    Reiter’s disease observed in an HTLV-1 carrier is reported. A 62-year-old man presented urethritis, conjunctivitis, arthritis, and skin lesions. The skin lesions were similar to pustular psoriasis and disseminated over his entire body. Circinate balanitis with pustules was also observed. Laboratory investigations revealed leukacytosis (18,600/mm3), an elevated ESR (62mm/h) and an elevated CRP level (4.7mg/dl). HLA-B27 was absent. Spongiform pustules were observed in the skin lesions The general symptoms disappeared after the administration of minocycline (200mg/day) and methotrexate (10mg/week). Treatment with etretinate (40mg/day) and PUVA was also effective in treating the recurring psoriasiform lesions. Recurrence of the skin lesions and arthritis appeared after the administration of etretinate was halted because of its adverse reactions. His skin lesions and arthritis have since been well controlled by the administration of cyclosporin with an initial dose of 5mg/kg/day and a maintenance dose of 3mg/kg/day. The response to these treatment modalities indicates that the skin lesions of Reiter’s disease characteristically demonstrate psoriasis. The anti-chlamidia antibody was initially negative but became positive at the time of recurrence of the skin lesions. Therefore, the chlamidia infection may have been a causative factor in this patient. The role of HTLV-1 infection, however, remains obscure.
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  • A Case of Sarcoidosis with Prominent Caseation Necrosis
    Shuji TAKASAKI, Toshio OKAMOTO, Satoshi ITAMI
    1995 Volume 57 Issue 6 Pages 1137-1141
    Published: December 01, 1995
    Released on J-STAGE: July 20, 2011
    DOIhttps://doi.org/10.2336/nishinihonhifu.57.1137
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    We report a case of sarcoidosis with caseation necrosis in a 38-year-old woman who presented with papular lesions on the face. A biopsy spesimen showed epithelioid granuloma with prominent caseation necrosis. Our tentative diagnosis was lupus miliaris disseminatus faciei. During the follow-up period of 7 months, alopecia on the parietal area and cervical lymphnode swelling were noticed. A histological examinations of these lesions also revealed the presence of epithelioid granuloma. Two years later, bilateral hilar lymphadenopathy was detected by chest CT.
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  • Three Cases of Clonal Seborrheic Keratosis
    Hajime SHINDO, Yuzo HAYASHI, Hirofumi MORIKAWA, Susumu SHINODA, Yasush ...
    1995 Volume 57 Issue 6 Pages 1142-1147
    Published: December 01, 1995
    Released on J-STAGE: July 20, 2011
    DOIhttps://doi.org/10.2336/nishinihonhifu.57.1142
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    Three cases of clonal type seborrheic keratosis are reported. In these cases, well defined nests of small basaloid cells were located within the acanthotic epidermis, and thus represented so-called intraepidermal epithelioma. Clonal type seborrheic keratosis is differentiated from hidroacanthoma simplex, which forms the similar small cell nests in the epidermis by papillomatosis, hyperkeratosis, and basaloid cells with no definite intercellular bridge in the nests fading into the surrounding keratinocytes. Of interest, all three lesions were observed on the patient’s thigh. In addition, their macroscopic features resembled those of such malignant lesions as Bowen’s disease and basal cell carcinoma.
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  • A Case of Langerhans Cell Histiocytosis
    —A Follow-up Study of LCH in a Case of Adult Onset—
    Kayoko YASUNO, Yoshihiro MAEKAWA, Atsushi NAKAMURA, Yoko SHIN, Reiko N ...
    1995 Volume 57 Issue 6 Pages 1148-1152
    Published: December 01, 1995
    Released on J-STAGE: July 20, 2011
    DOIhttps://doi.org/10.2336/nishinihonhifu.57.1148
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    A 63-year-old Japanese male with Langerhans cell histiocytosis (LCH) was reported. The diagnosis was confirmed from the histopathologic findings of LCH skin lesions on the right temple after the patient had been treated for diabetes insipidus for 15 years. This is a very rare case of adult onset, and a long follow-up study of LCH with skin lesions consisted of multiple, yellowish, and granulomatous subcutaneous nodules. Such lesions have not previously been described, as far as we could review, in the dermatological literatures.
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  • A Case of Multiple Endocrine Neoplasia Type 2B
    Tomoko NAKAO, Shonosuke NAGAE, Shuhei IMAYAMA, Yoshiaki HORI, Tomoko T ...
    1995 Volume 57 Issue 6 Pages 1153-1156
    Published: December 01, 1995
    Released on J-STAGE: July 20, 2011
    DOIhttps://doi.org/10.2336/nishinihonhifu.57.1153
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    A 41-year-old Japanese man with multiple endocrine neoplasia (MEN) type 2B, who also had medullary thyroid carcinoma presented with asymptomatic multiple neuromas on the lips, buccal mucous membrane, tongue and palpebral conjunctiva which developed during his childhood. The physical features of this patient were quite characteristic because of his thickened lips, swollen eyelids, hyperextensibility of the peripheral joints, and Marfan’s syndrome-like physique. A similar physical constitution was also seen in the patient’s mother and a younger brother.
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  • Systemic Contact Dermatitis due to Chloramphenicol
    —A Case Sensitized through an Ophtalmic Solution and Induced by the Vaginal Route—
    Tamano MATSUI, Tomomichi ONO, Masato KITO
    1995 Volume 57 Issue 6 Pages 1157-1159
    Published: December 01, 1995
    Released on J-STAGE: July 20, 2011
    DOIhttps://doi.org/10.2336/nishinihonhifu.57.1157
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    A 23-year-old Japanese woman developed characteristic systemic contact dermatitis due to chloramphenicol. She presented with both a pruritic maculopapular eruption around her right eye as well as edema in the intertriginous areas after using a vaginal tablet of chloramphenicol. Patch testing revealed positive reactions to chloramphenicol powder, vaginal tablets and ophtalmic solution. It was therefore assumed that the previously used chloramphenicol ophthalmic solution had sensitized this patient.
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Clinical and Investigative Report
  • The Distribution of the Tissue Polypeptide Antigen in Eccrine Sweat Gland Tumors
    Hsien-hsun YANG, Atsumichi URABE, Shonosuke NAGAE, Juichiro NAKAYAMA, ...
    1995 Volume 57 Issue 6 Pages 1160-1164
    Published: December 01, 1995
    Released on J-STAGE: July 20, 2011
    DOIhttps://doi.org/10.2336/nishinihonhifu.57.1160
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    The distribution of tissue polypeptide antigen (TPA) and human cytokeration 8, 18, 19 (PKK-1) in normal human skin and benign eccrine sweat gland tumors was studied using conventional immunohistochemical techniques. TPA was demonstrated in the inner cells of the ducts and the secretory portion of eccrine glands. PKK-1, which has a similar antigen to TPA, was demonstrated only in the secretory portion of the eccrine glands. As for eccrine sweat gland tumors, TPA localized in the tumor cells of nodular hidradenoma and mixed tumors of the skin. These findings thus suggested that the tumor cells were differentiated towards the inner cells of the ducts and the secretory portion of the eccrine glands. Both TPA and PKK-1 were localized in the large pale-staining cells of eccrine spiradenoma. It was thus thought that the tumor cells originated from the secretory portion of eccrine glands. Neither TPA nor PKK-1 were demonstrated in the poroid cells of eccrine poroma. Our findings therefore support the hypothesis that the poroid cells originate from the outer cells of the intraepidermal ducts and intradermal ducts of the eccrine glands.
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  • Bacterial Flora in Decubitus Lesions
    Tatsuya AKAKI, Katsunori DOI, Satoshi DEKIO, Joji JIDOI
    1995 Volume 57 Issue 6 Pages 1165-1169
    Published: December 01, 1995
    Released on J-STAGE: July 20, 2011
    DOIhttps://doi.org/10.2336/nishinihonhifu.57.1165
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    We investisated the bacteria in decubitus lesions from 57 inpatients at Muikaichi Hospital. Species and susceptibilities of these bacteria to some anti-bacterial agents were then determined. The main isolates from the mild cases were MSSA, while those from the cases with multiple lesions were MRSA. However, P. aeruginosa was frequently isolated from the cases with a single but large ulcer. Of interesting, in the susceptibility study of new quinolones, both the MRSA and MSSA strains fell into two groups, namely susceptible and resistant groups. In addition, the P. aeruginosa strains also demonstrated the similar findings.
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Review
Statistics
  • Leprosy Patients Observed at Ryukyu University Hospital Over the Past 10 Years (1982-1991)
    Atsushi HOSOKAWA, Hiroshi UESATO, Shigeo NONAKA, Hajime MIYASATO, Misa ...
    1995 Volume 57 Issue 6 Pages 1176-1183
    Published: December 01, 1995
    Released on J-STAGE: July 20, 2011
    DOIhttps://doi.org/10.2336/nishinihonhifu.57.1176
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    A total of 113 leprosy patients were observed at Ryukyu University Hospital during the past 10 years (1982-1991). The number of each type of leprosy were as follows: indeterminate leprosy (1), 9 (8.0%); tuberculoid leprosy (TT), 47 (41.6%); borderline tuberculoid leprosy (BT), 27 (23.9%); mid-borderline leprosy (BB), 11 (9.7%); borderline lepromatous leprosy (BL), 5 (4.4%); lepromatous leprosy (LL), 11 (9.7%); purely neural type, 2 and a primary lesion, 1. The number of newly-detected patients has gradually decreased. The percentage of TT, LL and cases in children has also decreased, while the number of borderline cases, especially BT and elderly cases have increased. The number of patients with disabilities, hand deformities and hair loss etc., was very small and the symptoms were generally mild. From these data, it was considered that the leprosy status in Okinawa Prefecture, where Ryukyu University Hospital is located has gradually shown epidemiological improvement over the past 10 years. However, small number of new patients with leprosy may still be seen because some child cases and indeterminate type cases still exist and relatively large number of middle aged cases was also detected. Recently, the number of foreigners with leprosy who came from endemic areas for this disease have also increased. Therefore, such cases may be seen in Okinawa in the near future.
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