Nippon Shokakibyo Gakkai Zasshi
Online ISSN : 1349-7693
Print ISSN : 0446-6586
Volume 110, Issue 4
Displaying 1-15 of 15 articles from this issue
Review article
Monthly report; New trends of Interventional EUS for the pancreato-biliary diseases
Round-table discussion
Original article
  • Shimpei MATSUSAKI, Masataka KIKUYAMA, Hiroshi KAWAKAMI, Kensuke KUBOTA ...
    2013 Volume 110 Issue 4 Pages 615-621
    Published: 2013
    Released on J-STAGE: April 05, 2013
    JOURNAL FREE ACCESS
    To clarify the clinical features and CT findings of IgG4-related sclerosing cholangitis (IgG4-SC), we reviewed 16 cases of IgG4-SC and 10 cases of cholangiocarcinoma concerning patient background, treatment, outcomes and CT findings. The median age of IgG4-SC cases was 70 (range 54-79) years, and only 1 was a woman. Serum IgG4 level of all IgG4-SC patients were elevated and in 13 patients steroid therapy proved effective. The CT findings were analyzed with regard to the biliary strictures (symmetry, outer margin, inner margin), wall enhancement pattern and pancreas size. The CT findings of symmetric wall thickness and total scores were significantly higher in IgG4-SC than in cholangiocarcinoma. Although the small number of patients in this study is a limitation, the CT findings may help distinguish IgG4-SC from cholangiocarcinoma.
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Case report
  • Haruka YOSHIDA, Hiroki TAKAHASHI, Katsuaki UKAI, Mikako SUGIMURA, Masa ...
    2013 Volume 110 Issue 4 Pages 622-629
    Published: 2013
    Released on J-STAGE: April 05, 2013
    JOURNAL FREE ACCESS
    A 70-year-old woman was admitted for investigation of an abdominal tumor. Abdominal CT revealed an ascending colonic mass measuring 10×10cm, with evidence of liver and lung metastasis. Colonoscopy revealed a cancerous lesion with a central ulcer in the ascending colon. Upper gastrointestinal endoscopy revealed an ulcerative lesion in the descending part of the duodenum. Histologically, the tumor showed features of neuroendocrine carcinoma. The patient died of the primary cancer two and a half months after admission. Autopsy revealed a fistula connecting the ascending colonic mass with the ulcerative lesion in the duodenum.
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  • Tasuku NAKABORI, Katsumi YAMAMOTO, Shiro HAYASHI, Mitsuhiko SHIBUYA, M ...
    2013 Volume 110 Issue 4 Pages 630-638
    Published: 2013
    Released on J-STAGE: April 05, 2013
    JOURNAL FREE ACCESS
    A woman in her seventies with multiple early stage (0-IIa) gastric cancers was undergoing imatinib therapy for gastrointestinal stromal tumor. Subsequently, she underwent 2-stage endoscopic submucosal dissection (ESD) for these cancers. Both procedures were successful, but she developed exfoliative esophagitis as a complication after the first ESD. To prevent this complication after the second ESD, we used a longer imatinib withdrawal period before the procedure and used general anesthesia during ESD. Although the patient developed exfoliative esophagitis after the second ESD, but its severity was less than that after the first procedure. Only a few studies have reported endoscopic therapy-induced exfoliative esophagitis. We suggest that this complication may be related to imatinib-induced mucosal damage.
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  • Ayako MATSUMOTO, Hiroyuki YAJIMA, Tomoya MURATA, Kousuke GOTOU, Kenta ...
    2013 Volume 110 Issue 4 Pages 639-647
    Published: 2013
    Released on J-STAGE: April 05, 2013
    JOURNAL FREE ACCESS
    A 30-year-old woman was referred to our hospital with recurrent refractory ulcerative colitis. She also suffered from avascular necrosis of the left femoral head caused by steroid use. We had expected that tacrolimus would contribute to remission, but effects remained insufficient even after 16 days of treatment. Intensive leukocytapheresis (LCAP) therapy was added to tacrolimus therapy, and this combination achieved remission. Tacrolimus plus intensive LCAP combination therapy appears useful in treating refractory ulcerative colitis.
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  • Kazuoki HIZAWA, Teppei HATADA, Susumu MORINAGA, Tetsuji KUDO, Mari NAK ...
    2013 Volume 110 Issue 4 Pages 648-654
    Published: 2013
    Released on J-STAGE: April 05, 2013
    JOURNAL FREE ACCESS
    An 80-year-old Japanese woman suffered multiple brain infarctions of unknown etiology during maintenance therapy of prednisolone and azathioprine for ulcerative colitis. Although a small cavity in the left lung spontaneously regressed, the patient suddenly died of massive brain hemorrhage due to disseminated aspergillosis, which was not identified until autopsy.
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  • Manabu SATO, Fuminori ONO, Akihiro YAMAMURA, Shoichi ONOCHI
    2013 Volume 110 Issue 4 Pages 655-659
    Published: 2013
    Released on J-STAGE: April 05, 2013
    JOURNAL FREE ACCESS
    A 67-year-old man was diagnosed to have sigmoid colon cancer with peritonitis carcinomatosa. The cancer was surgically resected, and he thereafter underwent chemotherapy with mFOLFOX6+bevacizumab. He complained of gingival swelling throughout treatment and osteonecrosis of the jaw was noted. The bevacizumab therapy was therefore discontinued and the necrotic tissue removed. No recurrent necrosis has occurred. The addition of bevacizumab to the FOLFOX or FOLFIRI chemotherapy regimens has been shown to improve the survival rate and response rate in colorectal cancer. Osteonecrosis of the jaw is a rare toxicity of bevacizumab. Bevacizumab might compromise the microvessel integrity in the jaw, which thus may lead to bone necrosis. Osteonecrosis of the jaw in this case recovered after the discontinuation of bevacizumab and the removal of the necrotic tissue. The pathogenesis and treatment of osteonecrosis have not been elucidated.
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  • Yukinari YOSHIDA, Nobuaki SUGAWARA, Takae MINAMI, Norikazu IWATA, Kimi ...
    2013 Volume 110 Issue 4 Pages 660-668
    Published: 2013
    Released on J-STAGE: April 05, 2013
    JOURNAL FREE ACCESS
    A 41-year-old woman who had a pancreatic tail tumor and multiple liver tumors was referred to our hospital. The results of abdominal US, CT and MRI, and histopathological and immunohistochemical findings of the liver tumor biopsy revealed a pancreatic neuroendocrine tumor with excessively-advanced liver metastasis. We treated her with S-1/gemcitabine combination chemotherapy plus long-acting somatostatin analogue octreotide, which produced tumor stabilization and good quality of life for 7 months, and survival time of 15 months. Although the tumor was diagnosed as a poorly differentiated endocrine carcinoma, this therapy was suggested to be effective in this case.
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  • Shinako TOCHITANI, Takahiro SENOH, Satoshi WAKASUGI, Nobuto HIRATA, Ma ...
    2013 Volume 110 Issue 4 Pages 669-678
    Published: 2013
    Released on J-STAGE: April 05, 2013
    JOURNAL FREE ACCESS
    A 42-year-old woman was admitted to our hospital with weight loss and right upper quadrant abdominal pain. Though an 8cm mass in liver segment 5/8 was detected by abdominal imaging, we could not confirm the diagnosis because findings on physical examination, blood chemistry, and radiologic examination were nonspecific. No cancer or immunocompromising diseases were found. We performed a liver biopsy because we were suspicious of a cold abscess caused by tuberculosis. Purulent material acquired from the biopsy revealed positive TB-PCR results, which confirmed the diagnosis of solitary liver tuberculosis. She received anti-tuberculosis medications leading to hepatic tumor resolution. There are very few reports of solitary liver tuberculosis diagnosed without surgery, thus we report this case of a solitary tubercle diagnosed by TB-PCR.
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