Nippon Shokakibyo Gakkai Zasshi
Online ISSN : 1349-7693
Print ISSN : 0446-6586
Volume 111 , Issue 10
Showing 1-12 articles out of 12 articles from the selected issue
Review article
Monthly report; Esophageal motor function in gastroesophageal reflux disease (GERD) and esophageal motility disorders
Round-table discussion
Case report
  • Yoichi AKAZAWA, Hiroya UEYAMA, Akihito NAGAHARA, Yuta NAKAGAWA, Kouhei ...
    2014 Volume 111 Issue 10 Pages 1968-1975
    Published: October 05, 2014
    Released: October 05, 2014
    JOURNALS FREE ACCESS
    A 66-year-old female underwent esophagogastroduodenoscopy, which revealed a 17-mm gastric submucosal tumor (SMT) located in the posterior wall of the upper area of the stomach. She was referred to our hospital for further investigation because of accumulation of radioactive substance in the gastric wall by PET-CT. CT gastrography (CTG) revealed three gastric SMTs in total. Partial gastrectomy was performed; histopathologically, they were diagnosed as gastrointestinal stromal tumor (GIST), benign schwannoma, and necrotic tissue. Gastric schwannoma is very rare, and we could find no cases with both GIST and schwannoma. Additionally, the three gastric SMTs were only detected clearly via CTG. We report on the details of this case and the usefulness of CTG for the detection of gastric SMT.
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  • Yuichi SHIMODATE, Kaori SUGIURA, Yousuke MITANI, Kyouko HAMAGUCHI, Aki ...
    2014 Volume 111 Issue 10 Pages 1976-1982
    Published: October 05, 2014
    Released: October 05, 2014
    JOURNALS FREE ACCESS
    A 79-year-old man was referred to our hospital complaining of weight loss. Esophagogastroduodenoscopy revealed a flat, elevated lesion of 30-mm diameter located on the posterior wall of the upper gastric body. The lesion was histologically diagnosed as a well-differentiated adenocarcinoma. Endosonography showed a submucosal tumor under the carcinoma, which was highly suspicious of a gastrointestinal tumor derived from the muscle layer. Adenocarcinoma was diagnosed as an intramucosal lesion, but laparoscopic fundectomy was performed because of the submucosal tumor. Pathological diagnosis was U, less, pType 0-IIa, 18×30 mm, pT1b (SM1), tub2, int, INFa, ly0, v0, pN0, H0, P0, CYX, M0, pStage IA, gastrointestinal stromal tumors, prognostic group 1.
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  • Chikara IINO, Tatsuya MIKAMI, Manabu SAWAYA, Kenta YOSHIDA, Tomoyuki A ...
    2014 Volume 111 Issue 10 Pages 1983-1989
    Published: October 05, 2014
    Released: October 05, 2014
    JOURNALS FREE ACCESS
    A 48-year-old man with colorectal cancer and right inguinal lymph node metastasis had previously undergone radiotherapy and chemotherapy (uracil/tegafur/leucovorin) after a colostomy in another hospital before being referred to us. Esophagogastroduodenoscopy (EGD) revealed the presence of a gastric metastatic lesion. After three courses of treatment with a modified regimen of leucovorin plus 5-fluorouracil plus oxaliplatin-6 (mFOLFOX6), EGD revealed that the gastric lesion had disappeared; computed tomography revealed that the size of the primary tumor and inguinal lymph node metastasis were markedly reduced. Subsequently, he underwent rectal resection of the primary tumor and continued treatment with mFOLFOX6 in combination with bevacizumab. We reviewed 29 similar cases from the literature, and determined that surgical resection of the tumor and appropriate chemotherapy can lead to long-term survival for patients with gastric metastases from colorectal cancer. Furthermore, positive CK20 and CDX2 expression and negative CK7 expression were useful adjuncts in the immunohistochemical diagnosis of gastric metastases from colorectal adenocarcinoma.
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  • Eisaku ITO, Shigeki WAKIYAMA, Yuki FUJIWARA, Masahiro IKEGAMI, Katsuhi ...
    2014 Volume 111 Issue 10 Pages 1990-1996
    Published: October 05, 2014
    Released: October 05, 2014
    JOURNALS FREE ACCESS
    A 76-year-old woman was diagnosed with intraabdominal tumors at a regular medical check-up. The tumors were resected and were identified as number 8a and 3 lymph nodes with adenocarcinoma. No primary was identified despite various studies; the final diagnosis was of adenocarcinoma of unknown primary. No recurrence developed; the patient has survived for 5 years without postoperative chemotherapy. The patient was disease-free 5 years after diagnosis. To the best of our knowledge, this is the first report of long-term survival of number 8a and 3 lymph node metastasis from an unknown primary carcinoma.
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  • Reona MORIO, Michio IMAMURA, Takayuki FUKUHARA, Hiromi KAN, Hatsue FUJ ...
    2014 Volume 111 Issue 10 Pages 1997-2003
    Published: October 05, 2014
    Released: October 05, 2014
    JOURNALS FREE ACCESS
    A 47-year-old man developed acute pancreatitis during combination treatment with telaprevir/peginterferon/ribavirin for chronic hepatitis C. Cessation of telaprevir, fasting, and gabexate mesilate improved the pancreatitis. Although peginterferon and ribavirin treatment was continued, there was no recurrence of the pancreatitis. Endoscopic retrograde cholangiopancreatography incidentally showed a pancreas divisum. We definitively diagnosed drug-induced acute pancreatitis due to telaprevir.
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  • Kosuke ISHIDA, Rika HORII, Tatsuya YAMASHITA, Kuniaki ARAI, Taro YAMAS ...
    2014 Volume 111 Issue 10 Pages 2004-2012
    Published: October 05, 2014
    Released: October 05, 2014
    JOURNALS FREE ACCESS
    An 81-year-old female was referred to our hospital for the examination of an S7 liver tumor. The tumor was suspected to be a hepatic adrenal rest tumor (HART) based on ultrasonography, dynamic CT, Gd-EOB-DTPA-enhanced MRI, and CT during abdominal angiography. After various hormonal tests, the tumor was confirmed as hormonally non-functional. The diagnosis of HART was confirmed based on 131I-adosterol accumulation in the tumor by adrenocortical scintigraphy. The resected tumor was histologically compatible with HART, and it may have been able to produce cortisol based on the immunohistochemical findings of various adrenocortical hormone metabolic enzymes. Adrenocortical scintigraphy may thus be useful in diagnosing HART.
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  • Shogo MATSUDA, Toshihiko KIRISHIMA, Naoki OKAMOTO, Yasuko HISANO, Koji ...
    2014 Volume 111 Issue 10 Pages 2013-2020
    Published: October 05, 2014
    Released: October 05, 2014
    JOURNALS FREE ACCESS
    A 54-year-old woman with hematemesis was referred to our hospital. She had a history of liver cirrhosis and diabetes mellitus. After inserting a Sengstaken-Blakemore tube, we performed endoscopic variceal ligation for ruptured esophageal varices. On the third day of admission, she developed septicemia and necrotizing fasciitis caused by Bacillus cereus. She was successfully treated with early debridement of both lower extremities and intravenous treatment with vancomycin, ciprofloxacin, and clindamycin. Although B. cereus is an attenuate bacterium, it can occasionally cause fatal infection in immuno-compromised individuals, such as those with liver cirrhosis.
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