Nippon Shokakibyo Gakkai Zasshi
Online ISSN : 1349-7693
Print ISSN : 0446-6586
Volume 112 , Issue 5
Showing 1-12 articles out of 12 articles from the selected issue
Review article
Monthly report; Current status and issues of acute liver failure
Case report
  • Yoshihiro SASAKI, Maiko HARADA, Shigeyuki KUROSAKI, Yusuke SHIMADA, Ma ...
    2015 Volume 112 Issue 5 Pages 848-855
    Published: May 05, 2015
    Released: May 05, 2015
    JOURNALS FREE ACCESS
    A 47-year-old man was found to have a type 2 tumor of the esophagogastric junction on upper gastrointestinal endoscopy. Biopsy specimens revealed squamous cell carcinoma of the esophagus and adenocarcinoma of the stomach. The preoperative diagnosis was a collision carcinoma. No distant metastases were identified on computed tomography; therefore, partial esophagectomy and gastrectomy were performed. Pathological examination of the resected specimen revealed adenosquamous carcinoma at the esophagogastric junction (TNM classification: stage IIA, T3N0M0). Adenosquamous cell carcinoma of the esophagus and stomach is rare, but that at the esophagogastric junction even rarer.
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  • Hiromi HAMAMOTO, Kosaku SAKAGUCHI, Shinichiro MURO, Kyo SASAKI, Sayo K ...
    2015 Volume 112 Issue 5 Pages 856-862
    Published: May 05, 2015
    Released: May 05, 2015
    JOURNALS FREE ACCESS
    A 21-year-old female presented at an emergency department with abdominal pain and nausea. Computed tomography (CT) of the chest and abdomen revealed a small amount of mediastinal emphysema in the precardiac area, but the underlying cause could not be identified. On admission, her plasma glucose was 371 mg/dl, glycated hemoglobin (HbA1c) was 14.0%, and blood pH was 6.91. These findings supported a diagnosis of Hamman's syndrome associated with diabetic ketoacidosis. Her diabetic ketoacidosis was managed with insulin and fluid therapy, and the mediastinal emphysema disappeared spontaneously by the time of discharge. Presence of free air of the chest and abdominal cavity must warrant a differential diagnosis of gastrointestinal perforation; however, when the free air is accompanied by diabetic ketoacidosis, it is not necessary to perform urgent endoscopy.
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  • Shinji MORII, Yoko DOI, Tomoo MAKITA, Shinichiro TAKEDA, Seiki MIURA, ...
    2015 Volume 112 Issue 5 Pages 863-870
    Published: May 05, 2015
    Released: May 05, 2015
    JOURNALS FREE ACCESS
    A 63-year-old woman with abdominal pain was referred to our hospital. Her pancreatic enzymes were elevated, and an abdominal computed tomography (CT) scan showed an enlarged pancreas, consistent with pancreatitis, and gas collection containing an impacted stone adjacent to Vater's papilla. This finding raised the suspicion of a duodenal diverticulum. A subsequent ERCP showed a juxtapapillary duodenal diverticulum (JPDD) filled with calculi and pus. The pancreatitis improved with 2 weeks of conservative treatment. Subsequently, the patient underwent resection of the uterus and bilateral adnexa to remove a large ovarian cyst that was also identified on the admission CT scan. On the third postoperative day, she developed abdominal pain and vomiting. CT revealed small bowel obstruction caused by an enterolith expelled from JPDD. Enterotomy was performed to remove the stone. To our knowledge, only three similar cases have been previously reported in Japan.
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  • Yoshihiro MORI, Sadatoshi SHIMIZU, Yukio NISHIGUCHI, Naomi ISHII, Take ...
    2015 Volume 112 Issue 5 Pages 871-879
    Published: May 05, 2015
    Released: May 05, 2015
    JOURNALS FREE ACCESS
    The administration of metronidazole is generally effective to treat amebic colitis. Fulminant amebic colitis is relatively rare, and it is associated with a high mortality rate. Three cases of fulminant amebic colitis were diagnosed in our hospital between 1993 and 2014. One of these patients died despite our efforts. Amebic colitis often presents with no obvious risk factors and with atypical clinical symptoms. Therefore, the diagnosis of amebic colitis can be difficult. Early diagnosis is the most important factor in successful treatment of fulminant amebic colitis. The present cases demonstrate that it is important to consider the possibility of amebic colitis during evaluation of the acute abdomen.
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  • Noboru TAKATA, Shuichi TERASAKI, Akira IWATA, Kenichi HARADA
    2015 Volume 112 Issue 5 Pages 880-887
    Published: May 05, 2015
    Released: May 05, 2015
    JOURNALS FREE ACCESS
    A 50-year-old woman with chronic hepatitis associated with hepatitis B virus was found to have a hypoechoic liver tumor of 20 mm in diameter on ultrasonography. Dynamic computed tomography and magnetic resonance imaging revealed multiple tumors in the liver. The portal vein passed through the tumor, which is not a typical feature of hepatocellular carcinoma. We subsequently performed tumor biopsy and diagnosed mucosa-associated lymphoid tissue (MALT) lymphoma of hepatic origin. Here we report this rare case of hepatic MALT lymphoma in a patient with chronic hepatitis B, and present a review of the literature.
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  • Taku MATSUO, Yukiko NAKAMURA, Koji SUZUKI
    2015 Volume 112 Issue 5 Pages 888-895
    Published: May 05, 2015
    Released: May 05, 2015
    JOURNALS FREE ACCESS
    A 73-year-old woman had received 9 months of chemotherapy with nab-paclitaxel for locally advanced breast cancer. During the treatment, she was well and showed no major side effects except for alopecia and arthralgia. The tumor showed a tendency to reduction. However, chemotherapy was discontinued because of liver dysfunction. MRCP and ERCP demonstrated multiple stenoses of the hepatic ducts and the intrahepatic bile ducts. We diagnosed chemotherapy-induced sclerosing cholangitis caused by nab-paclitaxel. Treatment with ursodeoxycholic acid and steroid was ineffective. We added bezafibrate, which resulted in a gradual improvement in liver function. To the best of our knowledge, this is the first reported case of nab-paclitaxel-induced secondary sclerosing cholangitis.
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  • Takayoshi MEGURO, Sayaka HASEKURA, Shiho KONDO, Yoshifumi MATSUMURA, N ...
    2015 Volume 112 Issue 5 Pages 896-904
    Published: May 05, 2015
    Released: May 05, 2015
    JOURNALS FREE ACCESS
    Two patients were referred to our hospital with cystic lesion (diameter 5 cm) of the pancreas and elevated serum CEA and CA19-9. We diagnosed them with malignant cystic neoplasms of the pancreas and performed distal pancreatectomy. Histologically, in both cases the cysts were lined with flat, transitional, squamoid cells without keratinization. Immunohistochemical staining confirmed two rare cases of squamoid cyst of the pancreatic ducts.
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  • Hiroyuki ASAMA, Tomohiro SUZUKI, Eisaku KITA, Nobuo MATSUHASHI, Osamu ...
    2015 Volume 112 Issue 5 Pages 905-913
    Published: May 05, 2015
    Released: May 05, 2015
    JOURNALS FREE ACCESS
    A 64-year-old woman who had undergone pancreatoduodenectomy for intraductal papillary mucinous carcinoma 10 months previously was referred to our department complaining of ascites and general malaise. Abdominal computed tomography (CT) showed a markedly decreased hepatic CT value. Liver biopsy revealed nonalcoholic steatohepatitis. Treatment with nutritional control and pancreatic enzyme supplements improved liver function. Exocrine pancreatic enzyme insufficiency from chronic pancreatitis is considered to be a cause of rapid progression of hepatic steatosis.
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