Nippon Shokakibyo Gakkai Zasshi
Online ISSN : 1349-7693
Print ISSN : 0446-6586
Volume 115 , Issue 6
Showing 1-10 articles out of 10 articles from the selected issue
Special contribution
Monthly report (General review article); Chemotherapy for gastric cancer: state of the art
Monthly report (Review article); Chemotherapy for gastric cancer: state of the art
Review article
  • Akihiro HAYASHI, Mirai EDANO, Kazunori MAEDA, Atsushi YANAGITANI, Kiwa ...
    2018 Volume 115 Issue 6 Pages 529-535
    Published: June 10, 2018
    Released: June 10, 2018
    JOURNALS FREE ACCESS

    Abdominal ultrasonography revealed a low echoic mass in the upper abdomen of a 65-year-old man. He was referred to our department, where abdominal CT revealed a tumor with a 30-mm contrast effect on the distal side of the inferior part of the duodenum. Endoscopy revealed a submucosal tumor in the same region, and ultrasonic endoscopy showed a low echoic mass with a clear boundary derived from the muscle layer. The duodenum was partially resected based on a diagnosis of suspected gastrointestinal stromal tumors (GIST), and the skin tumor was simultaneously resected. An elastic, soft, 30-mm tumor mass was found in the upper duodenum during surgery, and small nodules of 3-5mm were identified throughout the 110-cm length of the jejunum at intervals of 20-30cm. The histopathological diagnosis was GIST and immunostaining showed the mass to be c-kit and CD34 positive. We diagnosed the skin tumor as a neurofibroma (von Recklinghausen disease). Mutational analysis of c-kit in the resected specimen showed no mutation, therefore suggesting that imatinib would not be effective. Since the nodules remaining in the small intestine might also be GIST, we established a policy of regular imaging assessments.

    Download PDF (1271K)
  • Yuki NAKAMURA, Takahiro NOMI, Keiko MORIO, Takuki SAKAGUCHI, Yuichirou ...
    2018 Volume 115 Issue 6 Pages 536-543
    Published: June 10, 2018
    Released: June 10, 2018
    JOURNALS FREE ACCESS

    A 66-year-old man was hospitalized for diverticular bleeding of the colon. Anticoagulant drugs (Dabigatran and Beraprost sodium), which had been taken for chronic underlying atrial fibrillation, were interrupted for three days. After two months, he presented with acute pancreatitis and a pancreatic pseudocyst. The contrast-enhanced CT scan revealed an atrial thrombus and localized splenic infarction. Consequently, we suspected ischemic acute pancreatitis secondary to thrombus. Anticoagulant drug interruption and the resultant local ischemia were potential factors contributing to ischemic pancreatitis.

    Download PDF (907K)
  • Hirohito NARUSE, Norihiko SHIMOYAMA, Taiki KUDO, Yoshiya YAMAMOTO, Kaz ...
    2018 Volume 115 Issue 6 Pages 544-553
    Published: June 10, 2018
    Released: June 10, 2018
    JOURNALS FREE ACCESS

    We diagnosed distal cholangiocarcinoma in a 76-year-old woman who was then treated by subtotal stomach-preserving pancreaticoduodenectomy. Histopathological examination revealed a well-differentiated tubular adenocarcinoma on the side of the bile duct, and a neuroendocrine carcinoma in an area outside the bile duct where the tumor had infiltrated. Immunohistochemical staining identified homology between cytokeratins and MUC, indicating a similar origin. This report discusses problems associated with diagnosis and treatment by summarizing 22 patients who underwent curative resection and subsequently had a confirmed prognosis.

    Download PDF (2202K)
  • Keisuke TAKEMURA, Satoru SEKOGUCHI, Satoki YAMANE, Katsutoshi YAMAGUCH ...
    2018 Volume 115 Issue 6 Pages 554-562
    Published: June 10, 2018
    Released: June 10, 2018
    JOURNALS FREE ACCESS

    An 80-year-old man had a medical history of chronic hepatitis C and pancreatoduodenectomy. We detected recurrence of hepatocellular carcinoma, and performed transcatheter arterial chemoembolization, instead of radiofrequency ablation or surgery, because of the patient's medical history of bile duct reconstruction and liver dysfunction. On the second day, he was diagnosed with a gas-forming liver abscess and underwent liver abscess drainage. Clostridium perfringens and sordellii were detected by aspiration and the blood culture. Meropenem and Clindamycin were administered intravenously. He was treated shortly after the occurrence before the involvement of severe hemolysis and recovered from the acute phase.

    Download PDF (1036K)
  • Masataka YOKODE, Hideyuki SHIOMI, Ryosuke ITAI, Sakae MIKAMI, Yukimasa ...
    2018 Volume 115 Issue 6 Pages 563-572
    Published: June 10, 2018
    Released: June 10, 2018
    JOURNALS FREE ACCESS

    A referring hospital diagnosed a 57-year-old man with a pancreatic head mass. The initial endoscopic ultrasonography-guided fine needle aspiration (EUS-FNA) was inconclusive because of the small sample size. Endoscopic ultrasonography elastography (EUS-EG) and contrast-enhanced harmonic endoscopic ultrasonography (CE-EUS), conducted at our institute, raised the possibility of mass-forming pancreatitis or autoimmune pancreatitis (AIP). A repeat EUS-FNA revealed inflammatory changes, including a neutrophilic duct injury suggestive of type 2 AIP. The pancreatic lesion responded well to the steroid therapy. The present case suggests that EUS-EG and CE-EUS may be useful for diagnostic exclusion of pancreatic cancers, and the combined use of EUS-EG and CE-EUS, with EUS-FNA, may help characterize inflammatory pancreatic lesions.

    Download PDF (1705K)
feedback
Top