Nippon Shokakibyo Gakkai Zasshi
Online ISSN : 1349-7693
Print ISSN : 0446-6586
Volume 71, Issue 10
Displaying 1-11 of 11 articles from this issue
  • Toshiyuki TANABE
    1974 Volume 71 Issue 10 Pages 973-988
    Published: October 05, 1974
    Released on J-STAGE: June 17, 2011
    JOURNAL FREE ACCESS
    In recent years, the internal diagnostic techniques in the region of biliary tract, pancreas and duodenum have made a remarkable progress by percutaneous transhepatic cholangiography, hypotonic duodenography, endoscopic pancreatocholangiography and others. For this reason, an importance of organic changes of the papilla of Vater has been pointed out.
    In this report, the benign changes of the papilla of Vater (the lower end of the common bile duct) are histologically studied and histological relationship between the papilla of Vater and the pancreas is also studied from 67 autopsy materials of both sexes.
    The results are as follows:
    1) The diffuse fibrosis, round cell infiltration and glandular proliferation of the papilla of Vater with cholelithiasis showed to be more frequent than those of the papilla of Vater with control materials.
    2) The pathologic findings of the papilla of Vater can be classified into the 3 types-the type of inflammatory cellular infiltration, the type of glandular and/or fibrous proliferation and the type of adenosis (adenomyosis). The first type was frequently found in cholelithiasis, especially in choledocholithiasis.
    3) The histological changes of the papilla of Vater with aging have been observed.
    4) The intensity of the histological changes of the pancreatic duct and the interstitial tissue of pancreas with cholelithiasis was of the order of: head of pancreas>body>tail.
    5) The type of inflammatory cellular infiltration in the papilla of Vater has certain relation to the inflammatory changes of the pancreatic duct. The pancreatic duct inflammation correlates with the benign changes of the papilla of Vater. The changes of pancreatic duct also correlate with interstitial fibrosis and cellular infiltration of the pancreas.
    6) Cholelithiasis, benign changes of the papilla of Vater and pancreas are related to one another as studied pathohistologically.
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  • Masaharu TSUCHIYA, Kashu SHIMABUKURO, Hitoshi ASAKURA, Yoshio MIZUNO, ...
    1974 Volume 71 Issue 10 Pages 989-997
    Published: October 05, 1974
    Released on J-STAGE: June 17, 2011
    JOURNAL FREE ACCESS
    Immunological aspects of ulcerative colitis were studied, especially about possible role of thymus in this disease. Main subjects are 10 cases who were thymectomized. HL-A was investigated in 35 cases of Japanese ulcerative colitis including the thymectomized cases. And the following results were obtained.
    1. The thymus in ulcerative colitis was revealed as large radiopaque shadow in all cases by pneumomediastinography and pathologically 6 of 10 cases had lymphoid follicles. Incidence of lymphoid follicles in this disease was as high as in other autoimmune diseases.
    2. The lymphocytes in thymus had high T-cell population comparable to control children of congenital heart disease. Thymus in ulcerative colitis may be regarded as T-cell pool.
    3. DNCB test was decreased in 5 of 9 cases.
    4. T-cell population of peripheral lymphocytes was in normal range in most cases. Blastogenesis by PHA was decreased in 9 of 12 cases.
    5. Cellular hypersensitivity to colonic antigen was observed in 7 of 9 cases by leucocyte migration test according to Søborg.
    6. Incidence of HL-A 9 and HL-A 5 was statistically high in Japanese ulcerative colitis.
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  • Susumu TAGUCHI
    1974 Volume 71 Issue 10 Pages 998-1008
    Published: October 05, 1974
    Released on J-STAGE: June 17, 2011
    JOURNAL FREE ACCESS
    It has been demonstrated that the pancreozymin-secretin test (p-s test) is one of the most reliable method for the diagnosis of the chronic pancreatic diseases. The clinical significance of other factors except maximum bicarbonate concentration, especially that of the amylase output is not well established.
    It is demonstrated that pancreozymin which is used in the p-s test promotes the synthesis and secretion of enzymes in the pancreas cells. Therefore, an attempt was made to evaluate the enzyme synthetic and secretory activity of pancreas by use of75Se-Selenomethionine 2 hours before the p-s test, and clinical significance of amylase output was further investigated.
    The p-s test was performed on 38 patients who were injected with 6μCi of isotope per kg body weight and 11 patients who were received 0.5μCi per kg for scintiscanning of the pancreas. The same experiments were also made on rats.
    As the result, the radioactivity in the pancreatic juice was proved to be correlated well with the amylase output.
    The specific radioactivity of the protein isolated from the pancreatic juice showed normal value in the patients with normal amylase output, but was low in more than half of the patients with decreased amylase output. The same results were obtained in both groups injected with 6μCi and 0.5μCi per kg of75Se-Selenomethionine.
    This new method has proved advantageous over the p-s test hitherto used in diagnosing the enzyme secretory disorder as cited below.
    1) This method is very simple and reliable method as the test of exocrine function of the pancreas.
    2) This has made it possible to evalute the enzyme synthetic and secretory mechanism in the pancreas cells.
    3) It is conceivable that even a decrease in only one of the factors for the p-s test hitherto performed, namely, a decrease of the amylase output, represents abnormal excretory function of the pancreas.
    So it seems that this method makes it possible to diagnose the decrease of pancreatic function from the view point of synthetic activity of pancreatic enzyme.
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  • Hajime NOZAKI
    1974 Volume 71 Issue 10 Pages 1009-1022
    Published: October 05, 1974
    Released on J-STAGE: June 17, 2011
    JOURNAL FREE ACCESS
    For the purpose of elucidating immunological mechanisms of the onset of viral hepatitis and its course, 220 cases with various liver diseases and 20 normal subjects were investigated.
    Lymphoblastogenesis in tissue culture, dinitrochlorobenzen (DNCB) skin test, macrophage migration inhibition test, Mantoux reaction, peripheral lymphocyte counts andγ-globulin level were examined.
    The correlation between the results obtained and hepatitis B (HB) antigen were studied.
    Results obtained were as follows.
    1) Peripheral lymphocyte counts revealed no significant differences among subjects with various liver diseases.
    2) Cellular immunity was found to be depressed significantly in patients with liver cirrhosis (P=0.05) and those with chronic hepatitis with sublobular hepatic necrosis (P=0.05) when comparing with control.
    3) No obvious correlation between lymphocyte function and HB antigen was detected. It is still uncertain whether this is due to decreased sensitivity against the specific antigen or not.
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  • Yoshiaki MAEDA, Kuninori SOEZIMA, Shigeaki TAKEDA, Akira TAKAKI, Keiic ...
    1974 Volume 71 Issue 10 Pages 1023-1028
    Published: October 05, 1974
    Released on J-STAGE: June 17, 2011
    JOURNAL FREE ACCESS
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  • From Radiological and Endoscopical Viewpoints
    Susumu TORIIE, Masahiro TADA, Yoshihiro HASHIMOTO, Yoshihiro KOHLI, Ta ...
    1974 Volume 71 Issue 10 Pages 1029-1041
    Published: October 05, 1974
    Released on J-STAGE: June 17, 2011
    JOURNAL FREE ACCESS
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  • SS-Hepatic Arteriography
    Tsutomu TAKASHIMA, [in Japanese], [in Japanese], [in Japanese], [in Ja ...
    1974 Volume 71 Issue 10 Pages 1042-1049
    Published: October 05, 1974
    Released on J-STAGE: June 17, 2011
    JOURNAL FREE ACCESS
  • [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    1974 Volume 71 Issue 10 Pages 1050-1055
    Published: October 05, 1974
    Released on J-STAGE: June 17, 2011
    JOURNAL FREE ACCESS
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  • [in Japanese]
    1974 Volume 71 Issue 10 Pages 1056-1061
    Published: October 05, 1974
    Released on J-STAGE: June 17, 2011
    JOURNAL FREE ACCESS
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  • 1974 Volume 71 Issue 10 Pages 1061-1073
    Published: October 05, 1974
    Released on J-STAGE: June 17, 2011
    JOURNAL FREE ACCESS
    Download PDF (4279K)
  • 1974 Volume 71 Issue 10 Pages 1074-1083
    Published: October 05, 1974
    Released on J-STAGE: June 17, 2011
    JOURNAL FREE ACCESS
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