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Volume 90, Issue 11
Displaying 1-19 of 19 articles from this issue
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[in Japanese]1993 Volume 90 Issue 11 Pages 2857-2865
Published: 1993
Released on J-STAGE: December 26, 2007
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Shinji OHASHI, Shozo OKAMURA, Masahiro MITAKE, Hiroshi NAKAGAWA, Yasua ...1993 Volume 90 Issue 11 Pages 2866-2872
Published: 1993
Released on J-STAGE: December 26, 2007
JOURNAL FREE ACCESSThe utility of EUS was evaluated in 27 patients with early gastric cancer undergoing endoscopic mucosal resection over the past 2 years. Accuracy of the assessment of depth of cancerous invasion was studied in 16 patients undergoing EUS before endoscopic mucosal resection. Patients showing no changes in the submucosal (sm) layer or below on EUS included 15 with mucosal (m) cancer and one with sm cancer showing very slight infiltration. Seven patients with m cancer, a negative stump, and no ulcer in the cancer focus at endoscopic mucosal resection, were followed up for more than 1 year after endoscopic mucosal resection. On EUS, four patients showed Ul-IIs changes resembling benign ulcers, two showed Ul-IIIs changes and two showed no changes in the sm layer or below. All patients were negative for cancer in follow up biopsies. No lymphadenopathy was observed.
EUS was effective in diagnosing the depth of cancerous invasion in patients undergoing endoscopic mucosal resection and also in clarifying changes in the sm and deeper layers during follow up.View full abstractDownload PDF (2462K) -
Ichiro SUDO, Masaaki MIYAOKA, Toshihiko SAITO1993 Volume 90 Issue 11 Pages 2873-2881
Published: 1993
Released on J-STAGE: December 26, 2007
JOURNAL FREE ACCESSThe levels of fecal α1-antitrypsin (α1-AT) were significantly high in advanced gastric cancer patients, compared with those in healthy control subjects and early gastric cancer patients. As the background, a process was assumed that excessive α1-AT which flowed into the stomach through the cancerous lesion is saved from rapid proteolysis in the gastric juice of hypoacidity and proceeds to the small intestine. A molecular weight 38000 form of α1-AT was detected in all of the stools of the control subjects and the gastric cancer patients by Western blotting analysis, and which was shown to lack its sugar chain by crossed immunoelectrophoresis (CIE) and crossed immuno-affino-electrophoresis (CIAE) analysis.View full abstractDownload PDF (2396K) -
Hideki KOGA, Mitsuo IIDA, Kunihiko AOYAGI, Toshiyuki MATSUI, Masatoshi ...1993 Volume 90 Issue 11 Pages 2882-2888
Published: 1993
Released on J-STAGE: December 26, 2007
JOURNAL FREE ACCESSThe long term efficacy of low residue diet (LRD) for the maintenance of remission in patients with Crohn's disease was studied. The patients consisted of 60 with quiescent Crohn's disease who were given LRD (Clinimeal® or Ensure Liquid®) for maintenance therapy for more than one year (average 2.4 years) after discharge from our institute. On the basis of the quantity of LRD given per day, the patients were classified into three groups: A; O to 799 kcal a day, B; 800 to 1599 kcal a day and C; more than 1600 kcal a day. The remission rate and the avoidance rate of admission were calculated and compared among three groups. The remission rate in group C was significantly higher than those in groups A and B. The avoidance rates of admission in groups B and C were significantly higher than that in group A. These results suggest that drinking of LRD at home is useful for the maintenance of remission in patients with Crohn's disease and that the effect of LRD depends on the quantity of LRD given per day.View full abstractDownload PDF (779K) -
Etsuji SHIMADA, Tomoaki URAKAWA, Takashi UEDA1993 Volume 90 Issue 11 Pages 2889-2894
Published: 1993
Released on J-STAGE: December 26, 2007
JOURNAL FREE ACCESSThe coexpression of EGFR and c-erbB-2 protein was examined immunohistochemically in a total of 62 freshly frozen specimens of colorectal cancer, and correlations between the coexpression of both receptors and their clinicopathological variables were analyzed.
Positive staining of both receptors was found in 21 cases, and it was related to the degree of lymphatic or vascular invasion of cancer cell, the synchronous metastasis to liver or lung, and the most advanced stage (Dukes' D).
Moreover, the incidence of the distant metastasis including metachronous metastasis to other organs such as liver, lung or peritoneum were significantly higher in the positive cases of both receptors. These results suggest that the coexpression of EGFR and c-erbB-2 protein may be related to the distant metastasis of colorectal cancer.View full abstractDownload PDF (978K) -
Yasuki HABU, Takayoshi MATSUI, Kyohei HAYASHI, Yoshiyuki WATANABE, Kei ...1993 Volume 90 Issue 11 Pages 2895-2908
Published: 1993
Released on J-STAGE: December 26, 2007
JOURNAL FREE ACCESSA clinical decision analysis was performed to assess new therapeutic modalities for symptomatic gallstones with respect to patient's quality of life (QOL) and cost-effectiveness. A decision tree-based state transition model (Markov approach) implemented to simulate a five-year period of follow-up was constructed. Non-surgical treatments were superior to surgery in enhancing patient's QOL. This advantage was dependent upon the efficacy of non-surgical treatments (stone clearance rate) and patient's age. The optimal candidates were patients with a single radiolucent stone less than 2cm in diameter for extracorporeal shock-wave lithotripsy (ESWL), and patients with multiple floating stones for oral dissolution, respectively, especially in the elderly. ESWL was less cost-effective than laparoscopic cholecystectomy (LC). ESWL was superior to LC in enhancing patient's utility, but more expensive than LC. LC was economically cost-effective and superior to open cholecystectomy in enhancing patient's QOL for all eligible patients. LC appears to be the therapeutic modality of first choice for the majority of patients with symptomatic gallstones. In conclusion, the results of our analysis suggest the followings. Non-surgical treatments have an advantage over surgery in enhancing patient's QOL and are acceptable alternatives to surgery on the basis of their optimal indications and laparoscopic cholecystectomy is the new standard therapeutic modality in the treatment of symptomatic gallbladder stones.View full abstractDownload PDF (1751K) -
Akihiro TOYOKAWA, Yoshifumi TAKEYAMA, Hiromu HARANOMURA, Yoichi SAITOH1993 Volume 90 Issue 11 Pages 2909-2916
Published: 1993
Released on J-STAGE: December 26, 2007
JOURNAL FREE ACCESSWe examined the stimulatory state of peritoneal macrophages (Mφ) in caerulein-induced pancreatitis. Edematous pancreatitis was developed by the intravenous continuous injection of caerulein (5μg/kg/hr) for 4 hr. Thereafter peritoneal Mφ were collected and the activity for free radical production was measured by the reduction of nitro blue tetrazorium in the presence of phorbol myristate acetate. The increase in free radical production reached a statistical significance at 12 hr and a maximum at 20 hr after the beginning of caerulein infusion. These results suggested that the peritoneal Mφ are activated even in mild edematous pancreatitis, and that their activation is involved into the mechanism of the development of remote organ failure in acute pancreatitis.View full abstractDownload PDF (1814K) -
Kazushige UEDA, Hideharu TSUJI, Hiroshi HIKITA, Toshio YAMAMOTO, Yoshi ...1993 Volume 90 Issue 11 Pages 2917-2921
Published: 1993
Released on J-STAGE: December 26, 2007
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Shinichiro OBATA, Fumio KAWANO, Isao SANADA, Tetsuyuki KIYOKAWA, Keish ...1993 Volume 90 Issue 11 Pages 2922-2925
Published: 1993
Released on J-STAGE: December 26, 2007
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Seiji KIKKAWA, Koutarou HORI, Masayuki KITANO, Hirotaka MATSUMOTO, Mas ...1993 Volume 90 Issue 11 Pages 2926-2930
Published: 1993
Released on J-STAGE: December 26, 2007
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Shinji KATSUSHIMA, Tatsuya HIGASHI, Toshio TANIGUCHI, Yoshio KAWAGUCHI ...1993 Volume 90 Issue 11 Pages 2931-2935
Published: 1993
Released on J-STAGE: December 26, 2007
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Masanori KAMURA, Toshihiko NAGASHIMA, Tatsuyuki IMAI, Kyouichi FURUKAW ...1993 Volume 90 Issue 11 Pages 2936-2939
Published: 1993
Released on J-STAGE: December 26, 2007
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Takayoshi AKIYAMA, Yasuhiko KOJIMA, Masahiro MATSUSHITA, Kazuo KITABAY ...1993 Volume 90 Issue 11 Pages 2940-2944
Published: 1993
Released on J-STAGE: December 26, 2007
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The involvement of other multiple drugs such as Proheparum® and Mazulene-S® was considered in this drug-induced hepatitisNobuo HATAMORI, Taiki NAKAOKA, Hiroshi YOSHIDA, Hideki MIMOTO, Toshiya ...1993 Volume 90 Issue 11 Pages 2945-2950
Published: 1993
Released on J-STAGE: December 26, 2007
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Yasushi ADACHI, Toshiro SUGIYAMA, Akira OGAWA, Mitsuo SUGA, Tsuyoshi Y ...1993 Volume 90 Issue 11 Pages 2951-2955
Published: 1993
Released on J-STAGE: December 26, 2007
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Saburo SHIKUWA, Tadaaki KAMIYA, Masahiro SENJU, Hikaru TANAKA, Masuho ...1993 Volume 90 Issue 11 Pages 2956-2959
Published: 1993
Released on J-STAGE: December 26, 2007
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Akihiro TOYOKAWA, [in Japanese], [in Japanese], [in Japanese], [in Jap ...1993 Volume 90 Issue 11 Pages 2960
Published: 1993
Released on J-STAGE: December 26, 2007
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Kimihide NAKAMURA, [in Japanese], [in Japanese]1993 Volume 90 Issue 11 Pages 2961
Published: 1993
Released on J-STAGE: December 26, 2007
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Takahisa FURUTA, [in Japanese], [in Japanese], [in Japanese], [in Japa ...1993 Volume 90 Issue 11 Pages 2962
Published: 1993
Released on J-STAGE: December 26, 2007
JOURNAL FREE ACCESSDownload PDF (282K)
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