A study was performed on 28 cases of ischemic colitis. The patients were divided into three groups : Group A (9 cases with bloody stool detected within 2 hours after the onset of abdominal pain), Group B (7 cases with bloody stool detected in 2 to 6 hours), and Group C (12 cases with bloody stool detected after more than 6 hours). These cases were comparatively studied. Variables used were as follows : (1) age, (2) sex, (3) constipation, (4) vomiting, (5) peak value of WBC count (/μ
l) after admission, (6) peak value of log CRP (mg/d
l), (7) presence of ulcerative lesion in endoscopic findings in acute stage. Using Group A, B and C as classification variables, canonical discriminant analysis was perfomed. As a result, clear linearity was recognized in Group A→B→C, and the values (5), (6) and (7) were extracted as the corresponding variables. For these variales, significant difference was also noted in multivariate analysis of covariance. These results suggest that it is possible to predict the severity of the disease to some extent as represented by objective markers of inflammation by finding the time from onset of abdominal pain to detection of bloody stool.
View full abstract