Anaemia of mice, caused artificially by bleeding, can give rise to only slight reduction of liver catalase activity. Contrary to the facts observed in the experiments concerning the effect of iron upon the liver catalase depressing influence of this substance (III Report), an excessive demand of iron in anemic state augments the effect of this substance markedly.
Anaemic state in pregnant mice can cause more marked reduction of liver catalase activity than in nomal ones. Considering these facts, the author assumed that there is no marked reduction of liver catalase activity in normal pregnant mice, but they are more susceptible to the liver catalase depressing influence of this substance, and indirectly proved that there are liver catalase depressing factors in placenta.
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