In spite of the unkwnown pathogeny of the ulcerative colitis, the author points out 12 principles upon which rational treatment of this disease should be based; 1) Paramount importance of psychical treatment; 2) Treatment of neurovegetative dystonia 3) Treatment of infection with sulphonamides and antibiotics, with alternative administration of several kinds of the latters; 4) Transfusions of total blood is the only therapeutic measure to restore the loss of blood; 5) Diet should be aggreeable to taste; 6) Re-hidration must be co-related to the affected extra or intracellular sector; 7) Vitamin therapy should not be a supplement to the diet but of anti-inflammatory and healing character. Vitamins C and D₂ in large dosis are indicated with this purpose; 8) Medical ileostomy or “drip by drip treatment” of the author (1944) is excellent to control ulcerative lesions. Oleous clysters with prednisolone or prednisone and isoniazid have proven valuable. 9) ACTH and cortisone should be indicated without fearing side effects; 10) Treatment of concomitant diseases and complications is very important to a favorable evolution; 11) Surgical treatment depends on prognosis; 12) Surgical treatment should not be an effect of fear to malign degeneration.
Based upon these principles, the author classifies medical treatment of ulcerative colitis in general and local measures. Among the general measures, esteroids, antiallergic (tuberculostatics, azulens), sulphonamides (sulphisoxazol), antibiotics (chlortetracycline and chloramphenicol succinate), sales of gold, chlorochyne, estrogens, somatotrophine, enterogastrone and vitamins D₂, C and B₁₂ are valuable; their efficacy depends on each patient, therapeutical combination and intensity and oportunity of the management.
Surgical treatment is required not only in the presence of complications but also in special stages with bad prognosis. Technic of choice is a partial colectomy and simultaneous ileostomy with a minimal mortality rate.

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By way of the multiple layer centrifugation method which is mediated by solution of Gum Akashia and centrifuged for half an hour at 3, 000 r. p.m., cancer cells are separated from the material and the obstruction of cytodiagnosis are removed.
The distribution of the specific gravities of the solution floating cancer cells are not always simillar in all cases, but dissimillar in the kinds of the material.
In effusions, cancer cells are distributed at widest region.(10221060)
In sputum, they are distributed at narrow (1040-1055) than the mentioned above.
In materials of stomach are most limited.(1045-4055)
This dissimillarity of distribution is effected by the rate of keeping tho various degenerated cancer cells and by the general status on the experimental fluids.
The specific gravities of the solutions which are used clinically are enough with four solutions (1030, 1040, 1048, 1050) on effusions, and with three solutions (1040, 1045, 1055) on the sputa and the materials from stomach.

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Glucuronic acid contents of blood and excretion of glucuronic acid in the urine of normal adults, nephritic patients and hepatic patients, and glucuronide content of plasma and elimination of glucuronic acid in the urine of nephritic patients and hepatic patients were measured and the following results were obtained.
1. Glucuronic acid and sodium glucuronate were not absorbed by the peroral administration.
2. The more rapid increase and decrease of blood glucuronic acid were observed after the intravenous injection of sodium glucuronate than after the peroral administration of glucuronolactone.
3. Elimination of glucuronide glucuronic acid in the urine of normal adults was decreased after the intravenous injection of sodium glucuronate or the peroral administration of glucuronolactone.
4. After the intravenous injection of sodium glucuronate (0.5gm), 94% of gigen dose in normal adults, 89% of that in patients who had liver disease and 61% of that in nephritic patients were recovered from the urine within 24 hours.
5. After the peroral administration of glucuronolactone (2gm), 12% of given dose in normal adults, 7.7% of that in hepatic patients and 10.3% of that in nephritic patients were recovered from the urine within 24 hours.
6. In 13 casas of nephritic oatients and normal adulfs, a positive correlation (15 minute r=0.930 and 2 hours, r=0.832) was proved between excreted dose of free glucuronic acid in the urine within 24 hours after the intravenous injection of sodium glucuronate and excreted dose of PSP after the intravenous injection of the dye.
7. Elimination of glucuronic acid in the urine and glucuronide content of plasma in hepatic patients proved normal.
8. In 24 cases of nephritic patients especially who had intensive injurly of kidney, glucuronide content of plasma was increased and elimination of glucuronic acid in the urine was decreased as compared with normal value.
9. Diuresis and amelioration were recognized in nephritic patients following the daily intravenous injection of sodium glucuronate.

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