Neurologia medico-chirurgica
Online ISSN : 1349-8029
Print ISSN : 0470-8105
ISSN-L : 0470-8105
Search
Advanced search
OR
Browse
Search
Volume 47, Issue 1
Displaying 1-11 of 11 articles from this issue
Show all abstracts
    • |<
    • <
    • 1
    • >
    • >|
Original Articles
  • Histological Features of Middle Cerebral Arteries From Patients Treated for Moyamoya Disease
    Yasushi TAKAGI, Ken-ichiro KIKUTA, Kazuhiko NOZAKI, Nobuo HASHIMOTO
    2007 Volume 47 Issue 1 Pages 1-4
    Published: 2007
    Released on J-STAGE: January 24, 2007
    DOIhttps://doi.org/10.2176/nmc.47.1
    JOURNAL OPEN ACCESS
    Show abstractHide abstract
    Moyamoya disease (MMD) is a cerebrovascular occlusive disease characterized by progressive stenosis or occlusion at the distal ends of the bilateral internal carotid arteries. Vascular structural changes were previously detected using postmortem specimens. This study investigated 35 specimens of the middle cerebral artery (MCA) from 25 patients undergoing surgical treatment for MMD. Six MCA samples were also obtained from six control subjects. Histological examination showed that MCA specimens from patients with MMD had significantly thinner media and thicker intima than control specimens. In addition, abnormal findings of the internal elastic lamina and eosin-positive deposits in the intima were detected. Medial thinness and intimal hyperplasia occurred in the MCA of patients with MMD.
    View full abstract
    Download PDF (390K)
  • Growth Potential of Orbital Cavernous Hemangioma Suggested by Vascular Endothelial Growth Factor and its Receptor Flk-1
    Mitsuyasu NAGASAKA, Hirofumi NAGANUMA, Eiji SATOH
    2007 Volume 47 Issue 1 Pages 5-10
    Published: 2007
    Released on J-STAGE: January 24, 2007
    DOIhttps://doi.org/10.2176/nmc.47.5
    JOURNAL OPEN ACCESS
    Show abstractHide abstract
    Orbital cavernous hemangiomas (CHs) manifest as slowly developing symptoms indicative of slow growth. The present study investigated the involvement of angiogenic factors and their receptors in the growth of orbital CHs. Surgical specimens of orbital CHs were obtained from nine patients. Formalin-fixed, paraffin-embedded specimens were stained immunohistochemically using antibodies against Ki-67, CD31, α-smooth muscle actin (α-SMA), vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and VEGF receptors (flt-1 and flk-1). CD31 was expressed in the single layer of endothelial cells lining the vascular cavity. The thick vascular walls were positive for α-SMA, indicating that the vascular walls were smooth muscle cells. Ki-67 antigen immunostaining was mostly positive in the vascular walls and the staining index ranged from 0% to 6.8% (mean ± standard deviation, 2.7 ± 1.9%). VEGF and bFGF immunostaining were positive in all specimens. Flt-1 immunostaining was negative in all specimens, but flk-1 immunostaining was positive in both endothelial cells and smooth muscle cells. These results suggest that both VEGF and its receptor flk-1 are important in the growth of orbital CH.
    View full abstract
    Download PDF (488K)
  • Experimental Model Evaluation of Filter Trapping After Embolectomy Using the Merci System
    —Supplemental Technique for Merci Retrieval Procedure—
    Yasuhiro SUZUKI, Mitsuyuki FUJITSUKA, John C. CHALOUPKA
    2007 Volume 47 Issue 1 Pages 11-17
    Published: 2007
    Released on J-STAGE: January 24, 2007
    DOIhttps://doi.org/10.2176/nmc.47.11
    JOURNAL OPEN ACCESS
    Show abstractHide abstract
    Examination of embolectomy using the Merci® Retrieval System using experimental stroke models demonstrated that aspiration is not adequate to remove larger clots. The effectiveness of filter trapping was examined using the same models. A silicone model of the carotid artery system with model blood clot was incorporated in a laboratory pulsatile flow system. Embolectomy was performed using the Merci Retrieval System. Any clot not evacuated through the balloon guide catheter was trapped with a distal protection filter device developed for cervical stenting. The clot could not be sucked into the guide catheter by the recommended procedures in nine of 15 trials. Trapping failed in only one trial, in which the clot passed through a gap between the edge of the filter orifice and the inner model lumen. A clot was withdrawn to the catheter tip trapped across the edge of the orifice frame in one trial, and a very large clot was trapped across the filter orifice in two trials. Even clots made by the same method showed variation in properties, especially hardness, which may affect the effectiveness of aspiration. The aspiration procedure recommended for the Merci Retrieval System did not remove the large clots formed by embolectomy. The trapping procedure using a filter device without an orifice frame was effective to solve this problem.
    View full abstract
    Download PDF (356K)
Case Reports
  • Proximal Flow Arrest With Temporary Subclavian Steal for Internal Trapping of a Ruptured Vertebral Artery Dissecting Aneurysm
    —Case Report—
    Takehiro UDA, Keiji MURATA, Kazuhito NAKAMURA, Tsutomu ICHINOSE, Taro ...
    2007 Volume 47 Issue 1 Pages 18-21
    Published: 2007
    Released on J-STAGE: January 24, 2007
    DOIhttps://doi.org/10.2176/nmc.47.18
    JOURNAL OPEN ACCESS
    Show abstractHide abstract
    A 48-year-old woman presented with subarachnoid hemorrhage originating from a dissecting aneurysm of the left vertebral artery (VA). Internal trapping with proximal flow arrest was planned. The origin of the left VA was too tortuous to allow positioning of an occlusion balloon catheter and a microcatheter in the left VA via the femoral artery. Therefore, the temporary subclavian steal technique was used for proximal flow arrest, by placing an occlusion balloon catheter in the subclavian artery proximal to the VA origin via the femoral artery. Thereafter, coil embolization was achieved through the left axillary artery. The patient recovered well after the procedure.
    View full abstract
    Download PDF (314K)
  • Spinal Subdural Hematoma Following Intracranial Aneurysm Surgery
    —Four Case Reports—
    Myoung Soo KIM, Chae Heuck LEE, Seung Jun LEE, Jong Joo RHEE
    2007 Volume 47 Issue 1 Pages 22-25
    Published: 2007
    Released on J-STAGE: January 24, 2007
    DOIhttps://doi.org/10.2176/nmc.47.22
    JOURNAL OPEN ACCESS
    Show abstractHide abstract
    Four patients presented with rare spinal subdural hematoma (SDH) occurring after intracranial aneurysm surgery and manifesting as postoperative back pain. Magnetic resonance imaging performed from 4 to 11 days after the operation showed acute or subacute thoracolumbar SDH. No patient had risk factors for bleeding at this site (e.g., lumbar puncture, coagulation abnormality). Overdrainage of the cerebrospinal fluid (CSF) was performed for brain retraction during the operation in all four cases. Computed tomography performed during the postoperative period showed a suspicious tentorial subdural hemorrhage in Case 1 and an interhemispheric subdural hemorrhage in Case 3. All four patients received conservative management and their lumbago improved. We hypothesize that CSF hypotension due to overdrainage of CSF and downward migration of intracranial SDH under the influence of gravity were involved in the formation of spinal SDH.
    View full abstract
    Download PDF (215K)
  • Connection Between a Dural Artery and a Dural Vein in a Dural Arteriovenous Fistula of the Cranial Vault
    —Case Report—
    Emiko HORI, Naoya KUWAYAMA, Jun HARADA, Michiya KUBO, Hiromichi YAMAMO ...
    2007 Volume 47 Issue 1 Pages 26-28
    Published: 2007
    Released on J-STAGE: January 24, 2007
    DOIhttps://doi.org/10.2176/nmc.47.26
    JOURNAL OPEN ACCESS
    Show abstractHide abstract
    A 41-year-old man presented with consciousness disturbance and right hemiparesis. Computed tomography showed a hematoma in the frontal lobe. Left carotid angiography showed a dural arteriovenous fistula (AVF) located in the cranial vault, supplied by the left middle meningeal artery, and drained directly into the cortical vein adjacent to the superior sagittal sinus. Emergency decompressive craniectomy and evacuation of the intracerebral hematoma were performed. A red vein was found on the cortex but the location of the arteriovenous shunt was not clear due to severe brain swelling. Two months later, cranioplasty was performed and a part of the dura mater, expected to have been affected by the dural AVF, was resected. Histological examination disclosed thickening of the intima of the middle meningeal artery and a few small veins around this artery. The fistula was clearly demonstrated between the dural artery and the dural vein. The non-sinal type of dural AVF may originate in similar arteriovenous connections to the sinal type.
    View full abstract
    Download PDF (307K)
  • Combined Use of TruFill DCS Detachable Coil System and Guglielmi Detachable Coil for Embolization of Meningioma Fed by Branches of the Cavernous Internal Carotid Artery
    —Technical Case Report—
    Noboru KUSAKA, Takashi TAMIYA, Kenji SUGIU, Koji TOKUNAGA, Mitsuhisa N ...
    2007 Volume 47 Issue 1 Pages 29-31
    Published: 2007
    Released on J-STAGE: January 24, 2007
    DOIhttps://doi.org/10.2176/nmc.47.29
    JOURNAL OPEN ACCESS
    Show abstractHide abstract
    A 57-year-old female presented with a left petroclival meningioma fed by the meningohypophyseal trunk of the internal carotid artery (ICA). The enlarged tentorial marginal artery and inferior hypophyseal artery were successfully embolized with the TruFill DCS Detachable Coil System through a 0.019-inch inner diameter microcatheter. Superselective catheterization into the dorsal meningeal artery could not be achieved with the same microcatheter, because the catheter tip was too large to pass into the vessel. Subsequently the feeding artery was successfully embolized with a Guglielmi detachable coil (GDC) through a 0.016-inch inner diameter microcatheter. The patient underwent surgery without blood loss on the day after embolization. Our subjective impression was that the TruFill DCS was softer and had less resistance during insertion, whereas the GDC could be delivered through a smaller caliber system for smaller vessels. Appropriate use of the TruFill DCS and GDCs can allow efficient embolization of the feeding branches of the ICA.
    View full abstract
    Download PDF (402K)
  • Lymphoplasmacyte-Rich Meningioma With Atypical Invasive Nature
    —Case Report—
    Hidenori NOHARA, Kazuhide FURUYA, Nobutaka KAWAHARA, Akira IIJIMA, Kyo ...
    2007 Volume 47 Issue 1 Pages 32-35
    Published: 2007
    Released on J-STAGE: January 24, 2007
    DOIhttps://doi.org/10.2176/nmc.47.32
    JOURNAL OPEN ACCESS
    Show abstractHide abstract
    A 12-year-old boy presented with a lymphoplasmacyte-rich (LPR) meningioma in the posterior fossa. The tumor was subtotally removed. Histological examination showed the tumor had invaded the normal brain tissue despite its benign grade in the World Health Organization classification. The Ki-67 staining index using MIB-1 monoclonal antibody was relatively high. 18F-2-fluoro-2-deoxy-D-glucose positron emission tomography revealed high uptake in the tumor. These findings indicate the atypical nature of LPR meningioma.
    View full abstract
    Download PDF (611K)
  • Cervical Extradural En-plaque Meningioma
    —Case Report—
    Shuichi YAMADA, Shozo KAWAI, Taiji YONEZAWA, Katsuya MASUI, Noriyuki N ...
    2007 Volume 47 Issue 1 Pages 36-39
    Published: 2007
    Released on J-STAGE: January 24, 2007
    DOIhttps://doi.org/10.2176/nmc.47.36
    JOURNAL OPEN ACCESS
    Show abstractHide abstract
    A 22-year-old woman presented with a very rare extradural en-plaque spinal meningioma manifesting as right hemiparesis and gait disturbance. Magnetic resonance imaging revealed a well-enhanced lesion extending from the C-1 to C-5 vertebral levels, compressing the cord dorsally. Computed tomography revealed a slightly enhanced mass with calcification in the spinal canal, advancing in all directions except anteriorly. Surgery could not completely remove the part of the tumor that had progressed laterally. The histological diagnosis was cervical extradural en-plaque meningioma. Postoperatively, there was remarkable improvement in the patient’s symptoms. Successful treatment of this type of tumor requires the development of a combined surgical and radiosurgical approach.
    View full abstract
    Download PDF (207K)
  • Neurocysticercosis as Solitary Parenchymal Lesion Confirmed by Mitochondrial Deoxyribonucleic Acid Sequence Analysis
    —Case Report—
    Eiichi ISHIKAWA, Yoji KOMATSU, Kazunori KIKUCHI, Hiroshi YAMASAKI, Hir ...
    2007 Volume 47 Issue 1 Pages 40-44
    Published: 2007
    Released on J-STAGE: January 24, 2007
    DOIhttps://doi.org/10.2176/nmc.47.40
    JOURNAL OPEN ACCESS
    Show abstractHide abstract
    A 38-year-old Japanese woman presented with neurocysticercosis manifesting as mild hemiparesis. Magnetic resonance (MR) imaging with gadolinium showed a solitary parenchymal lesion. MR spectroscopy of the mass showed a relatively low N-acetylaspartate peak. Enzyme-linked immunosorbent assay of the patient’s cerebrospinal fluid using antibodies against several parasite antigens was negative. Surgical resection of the lesion was performed. The histological findings showed the possibility of parasitic infection such as neurocysticercosis, although the definitive type of parasite was not confirmed. Sequencing of cytochrome c oxidase subunit 1 gene of mitochondrial deoxyribonucleic acid indicated the Asian genotype of Taenia solium. We propose that these new diagnostic techniques should be used more widely, especially for solitary lesions of neurocysticercosis.
    View full abstract
    Download PDF (658K)
Editorial Committee
    • |<
    • <
    • 1
    • >
    • >|
feedback
 Top