巻号一覧
69 巻, 5 号
選択された号の論文の4件中1～4を表示しています
- |<
- <
- 1
- >
- >|
-
Sanae ICHIKAWA, Noriyuki EDA, Shigeo UCHINO1992 年 69 巻 5 号 p. 199-207
発行日: 1992/12/21
公開日: 2012/09/24
ジャーナル フリーIntimate association of peptidergic nerves with lymphocytes of canine and monkey ileal villi was demonstrated by immunohistochemistry and transmission electron microscopy. A swollen, presumably terminal, portion of nerves containing large cored vesicles and small clear vesicles was in direct contact with a lymphocyte. The apposing membranes of the nerve and lymphocyte were thickened and darkened, being separated by a narrow uniform space. The lymphocyteassociated nerves contained immunoreactivity for substance P(SP), calcitonin gene-related peptide (CGRP) or vasoactive intestinal polypeptide (VIP), localized in large-cored vesicles. These result support the hypothesis that peptidergic nerves may play a regulatory role in mucosal immune responses.抄録全体を表示PDF形式でダウンロード (4584K) -
Gang NING, Masahiro SAKAI, Kazuo OGAWA1992 年 69 巻 5 号 p. 209-215
発行日: 1992/12/21
公開日: 2012/09/24
ジャーナル フリーUsing a fixative of low concentrated glutaraldehyde in PIPES, we examined three-dimensional structures of acid phosphatase (ACPase) activity in the cells of testes of normal adult and 30 min heat-treated rats by high voltage electron microscopy. There were less ACPase-positive structures in germ cells, but more in Sertoli cells, particularly in residual bodies, and also in macrophages lying between seminiferous tubules. Reaction products of ACPase were distributed in the trans-most cisternae of Golgi apparatus, many spherical lysosomes, and acrosomes. The elongated thread-like lysosomes (nematolysosomes) were absent on the testicular cells. After heat-treatment of rat testis, though ACPase-positive lysosomes increased in number, nematolysosomes were never seen in Sertoli cells and most of the other testicular cells; a number of rod-like lysosomes, however, emerged in macrophages. The results indicate that (1) Sertoli cells usually have more ACPasepositive lysosomal contents than germ cells; (2) Sertoli cells are less affected by stress which may largely hurt germ cells; (3)nematolysosome is not a ubiquitous structure in all the types of cells; and (4) the function of nematolysosomes in macrophages may involve in the disposition of disintegrated cells in rat testis.抄録全体を表示PDF形式でダウンロード (2401K) -
Takuma SAITO, Toshimitsu ISHIBASHI, Kyotaro KANAZAWA1992 年 69 巻 5 号 p. 217-224
発行日: 1992/12/21
公開日: 2012/09/24
ジャーナル フリーThe distribution of glucose-6-phosphate dehydrogenase (G6PD) activity has been studied by a copper ferrocyanide method in the adrenal cortex cells of a rat. The site of the G6PDH activity was close to the ribosome between the round mitochondria of zonas fasciculata and reticularis.抄録全体を表示PDF形式でダウンロード (3585K) -
K. TAKANO, D. MALAMUD, A. R. HAND1992 年 69 巻 5 号 p. 225-238
発行日: 1992/12/21
公開日: 2012/09/24
ジャーナル フリーMonoclonal antibody 303 (mAb 303) reacts with the high molecular weight agglutinin present in human saliva. Its reactivity is periodate sensitive, and it has been shown to recognize the Y epitope. Immunogold labeling of thin sections of human parotid and submandibular glands with mAb 303 showed reactivity in secretory granules of serous acinar, intercalated and striated duct cells (Takano et al.,1988). We now report that the apical and basolateral membranes of salivary acinar and duct cells are labeled by mAb 303, but not myoepithelial cells, endothelial cells and other mesenchymal cells. Gold particles were confined to acinar and duct cell membranes even when myoepithelial cells were directly adjacent, suggesting that the epitope resides on a membrane glycoprotein and that the label does not represent secreted agglutinin bound to the cell surface. Although myoepithelial cells are thought to differentiate from epithelial stem cells, the present results indicate that substantial compositional differences exist between the membranes of myoepithelial cells and other salivary parenchymal cells. Earlier studies also showed that mAb 303 labels normal pancreatic acinar cells and certain salivary (pleomorphic adenoma)and mammary (lactating adenoma) tumors (Bogert et al.,1988). This antibody thus may be a useful reagent for characterizing the origin of exocrine gland-derived cell cultures and neoplastic cells. Further, localization studies may provide insight into the role of the Lewis blood group-related epitope in secretory cells.抄録全体を表示PDF形式でダウンロード (7067K)
- |<
- <
- 1
- >
- >|