The method to examine the middle ear conduction system using Acoustic probe is in wide use since Zoellner reported it in 1951. Recently criticism is heard louder that the method, by which the examiner holds Acoustic probe in his hand, results in greater biometric errors with less clinical implication for cumbersome procedure. The author developed his own Acoustic probe. It was aimed for quantitative recording of minute changes of the middle ear conduction system by applying pressure to the sound tip. And the hearing test by Acoustic probe was re-evaluated. One hundred diseased ears were tested by this new apparatus. It was shown that the new method enabled the sound to keep stable pressure on the tip and produced dependable results. The maneuver was simple and easy. Furthermore, loading test doje by this method showed that mobility of the middle ear conduction system in some cases was not so poor as it was thought to be by the previous method.
Four cases of the nasal polyps and 8 of the paranasal sinusitis were treated by Minatohl-P administered by mouth. Effects of Minatohl-P were studied histopathologically. Results were as follows 1) The polyp decreased its size in one patient and histologic inflammatory picture regressed in 2. 2) Marked clinical improvements were noted on all patients with acute para-nasal sinusitis. 3) With use of Minatohl-P for chronic para-nasal sinusitis, two patients reduced pus of the maxillary sinus and three patients showed moderate histologic improvements of the inflammatory maxillary mucosa. Length of the treatment was thus shortened.
Fourty two cases with catarharic Eustachitis, allergic rhinitis or both catarharic rhinitis and para-nasal sinusitis combined were treated by Cephalantin, administered orally 6mgm. a day for 2 to 5 weeks. Clinical effects and progress were carefully followed. It was shown that Cephalantin was quite effective on 16 cases (38%), effective on 16 (38%) and not effective on 10 (24%). Among the diseases treated, catarharic rhinitis, allergic rhinitis and catarharic Eustachitis responded favourably, particularly in acute and early phase. For the chronic cases, it was necessary to administer for longer period but complete cure appeared to be remote. However, no side effect was recognized by the use of Cephalantin.
Allergic rhinitis and acute or chronic rhinitis occuring in the allergic patients were treated by Cephalantin. Twenty such patients were selected and 3 to 10 mgm. of Cephalantin were administered orally. It was found that efficacy of Cephalantin was the greatest for the acute rhinitis and was not uniform and dependable for the chronic rhinitis. For the allergic rhinitis, it seemed in majority of the patients that Cephalantin was effective only when Cephalantin was in use. The effects were mainly evaluated by four symptons-sneezing, watery rhinorhea, nasal obstruction and heavy feeling of the head. Lastly optimal duration of the administration was discussed and so was simultaneous use of other drugs.
The nasal polyps were treated by injecting 2ml. of 3% or 5% of Chondron solution. For the control, 2ml. of normal saline was injected and results were compared. Both injections were repeated for 20 times. Symptomatic relieves of nasal obstruction, rhinorhea and olfactory disturbance were looked for and pathologic examinations were done on some nasal polyps. Seventy-five percent of the polyps treated demonstrated objective decrease in size, while 50% of the patients enjoyed subjective improvement of the rhinorhea. With use of the normal saline some showed temporaly symptomatic relief. The relief, it was shown by the pathologic examinations, was brought by the fact that polyps reduced in size because of proliferation of the connective tissue with Chondron injections. With use of the saline, contents of the polyps were mechanically evacuated and the polyps, shrunk. In treating the nasal polyp, senile or hypertensive patients who can not tolerate routine surgery are indication of the Chondrone injections. It is worth to remember that the injections can be given in the out-patient clinic.
Glifanan, which was known to have anti-inflammatory and analgesic actions, were used for pain due to either inflammation (16 cases) or operation (18 cases). Seventy to ninety percent of the patients treated showed analgesic response. With larger initial dose (600 to 800mgm.), it was found that the more satisfactory analgesic effects could be expected and less dose was required for the maintenance. In majority of the cases the analgesic effects took place 30 minutes after the administration for the inflammatory pain, while it took more than 50 minutes for the postoperative pain. Side actions, observed on 40% of the cases, were anorexia and nausea. The administration is better interrupted with these side effects. In case Glifanan is used as an anti-inflammatory agent, the dose can be economized with simultaneous use of antibiotics.