The rate and degree of occurrence of the eosinophil leukocyte and plasma cell in the nasal polyps obtained surgically from 175 patients were investigated histopathologically. Varying degrees of the eosinophil infiltration were noted in 60% of the patients, and plasma cells were observed more or less in 88% of the patients, suggesting that some allergic factors might be involved in the polyp formation in the nasal cavity. Relatively high degree of the infiltration of both inflammatory cells was detectable in the edematous type of the polyps. However, little infiltration of these cells was seen in the fibrous polyps. The pertinent literature of the eosinophil leukocyte and plasma cell in the nasal polyps was discussed briefly.
We recorded changes of nasal respiratory resistance by continuous nasal stimulation by inhalation of methacholine in time course using asthgraphy and then estimated quantitatively hyperresponsiveness of the nasal mucosa. The obtained asthgram was analyzed to obtain the following 3 indexes: initial nasal respiratory resistance (Rrs. cont), integrated dose until the point where the respiratory resistance begins to raise (Dmin), Sd (ΔRrs/Dose) calculated from the increase in resistance after one minute inhalat ion from Dmin (ΔRrs) and the dose during that period (Dose). Here Rrs. cont indicates nasal respiratory resistance immediately before provocation, Dmin indicates sensitivity of nasal mucosa and Sd reflects reactivity of nasal mucosa. Non-specific nasal provocation test was performed by asthgraphy, and dose-response curves were analyzed in the group of nasal allergy having anamnesis of bronchial asthma during childhood, the group of allergic rhinitis and the group of non-airway allergy. As a result, these 3 groups were clearly discriminated. There was no difference in Rrs. cont among the 3 groups, but Dmin was the lowest in the group of nasal allergy having anamnesis of bronchial asthma, followed by the group of allergic rhinitis and the group of non-airway allergy, becoming higher in this order. Sd was the largest in the group of nasal allergy having anamnesis of bronchial asthma, becoming smaller in the order of the group of allergic rhinitis and the group of non-airway allergy. From the above results, it is considered that hyperresponsiveness of the nasal mucosa consists of two factors, i.e. sensitivity and reactivity.
Various nasal and sinus operations are grouped under three different categories, then the efficacy of each group for the improvement of nasal obstruction has been evaluated. All the three groups proved to be effective for alleviation of nasal obstruction however, the group with simple submucous resection together with conchotomy group has been found to be less effective when compared with the other groups with treatment of the sinus pathology. It is suggested, in dealing with nasal obstruction, that one should be aware of the pathological conditions in the upper part of the nasal cavity as well as the lower part, mucosal pathology of the paranasal sinuses and psychological aspects on the patients.
ENG recording was performed in cases of Meniere's disease during vertiginous attack using a newly devised long recording portable electronystagmograph which was capable of recording nystagmus on a cassette tape f or over 24 hours. The ENG findings were as follows: 1) In some cases nystagmus recorded during attacks changed the direction, but in other casesnystagmus recorded during attacks did not change the direction. 2) Nystagmus during attacks appeared and disappeared periodically. 3) In one case, ENG recording could fortuitously be performed before an attack and till the end of it. Nystagmus directing to the affected side was recorded before the attack and in the begining of the attack, and nystagmus directing to the non-affected side was recorded about the middle of the attack, and then nystagmus directing to the affected side was recorded again at the end of the attack.
1) One hundred and five cases of laryngeal carcinoma consisting of 68 glottic cases, 36 supraglottic cases and one subglottic case were treated at the department of otolaryngology, Sapporo Medical College, from January 1, 1976 to December 31, 1982. 2) The most frequent symptom of the glottic cases was hoarseness, and those of supraglottic cases were sore throat and hoarseness. The mean interval before visiting our clinic was 20 months in glottic cases and 6. 6 months in supraglottic cases. 3) Cumulative survivals of all cases were 67. 6% at 3 years and 59.7% at 5 years. 4) Radiotherapy was very effective for T1N0 and T2N0 cases. Combination of radiation and surgery was the most effective treatment for T3 cases. 5) Recurrence appeared in 61.5% within one year in the glottic cases. 6) The causes of death were neck lymph nodes recurrence (34.2%) failure in local tumor control (23.6%) and distant metastases (21.0%).
This study included 109 cases of chronic otitis media with cholesteatoma (pars flaccida type, 69 cases pars tensa type, 27 cases and others, 13 cases) and 160 cases of chronic otitis media without cholesteatoma. The results of the present study are as follows: 1. The location of ossicular erosion was mostly at the region where a cholesteatoma matrix had invaded. It was recognized that the lateral side of the malleus and incus were usually found to have been resorbed at the early stage, followed by the destruction of malleus head, incus body and short process in the cholesteatoma of pars flaccida type. On the other hand, the medial side of the malleus and incus including I-S joint were usually found to have been resorbed in the cholesteatoma of pars tensa type at the early stage. Generally, the extent of ossicular erosion in the cholesteatoma of pars tensa type is much more severe than that of pars flaccida type, therefore, all the ossicles had completely disappeared in many cases with pars tensa type. It was noted that the resorption had been found mainly about the I-S joint in chronic otitis media without cholesteatoma. 2. The bony walls of the mastoid cavity were frequently resorbed in the cholesteatoma of pars flaccida type. The bony walls of the hotizontal portion of the facial nerve were resorbed in the cholesteatoma of pars tensa type. 3. The I-S joint was frequently resorbed as a result of the presence of severe inflammatory changes at the postero-superior portion of the tympanic cavity in chronic otitis media without cholesteatoma.
PTP (press through pack) has been knwon as a frequent cause of a foreign body in the esophagus in elederly patients who occasionally swallow a medicine still contained in a PTP inadvertently. The author reports a method for removal of a PTP foreign body from the esophagus without causing injuries to the walls of the esophagus. The author attached a short silicone tubing at the end of a esophagoscope, and managed to contain a PTP foreign body into the tubing before it was retracted together with the esophagoscope. This method would be applicable to other foreign bodies with sharp edges lodging in the esophagus.