A review of operation records of 571 cases with chronic otitits media for an attempt to study tympanosclerosis revealed the following; 1. the incidence of tympanosclerotic lesions was greater in simple chronic otitis media than in cases with cholesteatoma or adhesive otitis, 2. male to female ratio was 2 to 1, 3. tympanosclerotic lesions of the eardrum, in most cases, were associated with the same lesions within the middle ear. 4. tympanosclerosis was confined to the pars tensa and in no case occurred in the pars fiaccida, 5. the lesion in the tympanum was frequently seen at stapes-oval window area, I-S joint and attic. 6. in the majority of cases the tympanosclerosis was associated with thin and dry middle ear mucosa, 7. audiograms of the ear with tympanosclerosis showed stiffness curves.
The authors report six cases of tuberculous otitis media seen during the past seven years at the university hospital. One of the characteristics in the development of tuberculous otitis media in recent years appeared to be that the disease developed in the ears with preexistent nonspecific chronic otitis media, in contrast to the tuberculous otitis media in pre-antibiotic era, which had often been a complication of systemic tuberculous disease.
The authors report a rare case of cancer of the ethmoid sinus developing in a patient in whom cancer of the contralateral sphenoid sinus had been successfully treated with surgery and irradiation ten years prior. A review of literature of cancer of the ethmoid sinus is presented.
A comparison was made between the results of surgical treatment (endonasal ethmoidectomy) and conservative treatment (betmaethazore nose drip, orally administered ethylcysteine-HCl and serratiopeptidase or pronase) in patients with chief complaints of olfactory disturbance caused by localized ethmoiditis. The group receiving surgical treatment contained 8 patients and one receiving conservative treatment contained 14 patients. The patients given each treatment were observed for 3 months. The effect of each treatment was evaluated at 3 months firstly. The improvementment rate was 62.5% in the surgically-treated group and 50.0% in the group given conservative treatment. There was no statistically significant difference between the two groups. Secondly the effect was evaluated at 6 and 9 months. As to long-term prognosis, the surgicallytreated group contained half of patients who showed complete improvement and required no further treatment. On the other hand, the patients given conservative treatment showed increased hyposmia with repeated attacks of common cold, so the prognosis was poor. It is concluded that olfactory disturbance with localized ethmoiditis should be treated surgically and that conservative therapy shoulpbe given over an extended period of time. In 2 patients in whom biopsy of the olfactory epithelium was performed, the olfactory component (comprised of supporting cells, olfactory cells and basal cells) showed no specific abnormal changes. On the other hand, there was various inflammatory changes in respiratory epithelium near the olfactory epithelium.