It has often been said that it is difficult to accurately determine the primary lesion when a malignant lymphoma occurs.
However, in view of the nature of the or primary lesions, it is conceivable that malignant lymphomas can develop in organs other than lymphatic glands. The following are the findings obtained from our clinical experience in the treatment of two patients with malignant lymphoma which was presumed to have originated in the maxillary sinus.
The patients were a 57-year-old female and a 76-year-old male each of whom was diagnosed as essential malignant lymphoma (large cell type) of the right maxillary sinus. The former was treated with VEPM method, and the latter with BACOP and COP methods and radiotherapy. However, both patients died of septicemia which developed approximately 6 months after the treatment was initiated.
Malignant lymphoma is often accompanied by primary symptoms such as nasal obstruction and or buccal swelling. However, it is difficult to distinguish local symptoms from those of caricinoma because of lack of symptom specificity. It is, therfore, necessary for physicians to accurately determine the duration of the disease and the type of the tissues involved.
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