加速器
Online ISSN : 2436-1488
Print ISSN : 1349-3833
22 巻, 2 号
選択された号の論文の16件中1~16を表示しています
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  • 岩田 佳之
    2025 年22 巻2 号 p. 110-118
    発行日: 2025/07/31
    公開日: 2025/07/31
    ジャーナル フリー

    Radiotherapy using high-energy carbon beams from the Heavy Ion Medical Accelerator in Chiba (HIMAC) has been carried out at the National Institute of Radiological Sciences (NIRS) since June 1994, and more than 17,000 patients were treated by now. With the prospective clinical results for the first ten years, we designed a compact accelerator facility for carbon-ion radiotherapy (CIRT), and performed related Research and Development (R&D) works for widespread use of CIRT since 2004. Based on the design and the R&D works, five compact facilities for CIRT were constructed and are in treatment operation, and furthermore the compact facilities are being constructed around the world. To further develop the sophisticated CIRT, we constructed a new treatment facility at NIRS. This new facility is equipped with three treatment rooms; two of them have both horizontal and vertical fixed-irradiation-ports, and the other is a rotating-gantry port. For all ports, fast 3D raster-scanning irradiation technology is employed. Presently, we are further designing a next-generation compact facility as a future project; superconducting and laser technologies are to be used for accelerator design. In this article, a review of the medical accelerator development for carbon-ion radiotherapy is described in celebration of the 30th anniversary of HIMAC.

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加速器と社会
  • 畑澤 順
    2025 年22 巻2 号 p. 132-136
    発行日: 2025/07/31
    公開日: 2025/07/31
    ジャーナル 認証あり

    Innovation of nuclear medicine practice is ongoing. It is a theranostics of PET and SPECT imaging-based radioisotope (RI) therapy. In this process, stable supply of RIs is a key issue. Current international supply chain of medical RI is at risk of shortage in spite of increasing needs. Accelerators are expected to produce medical RI and to contribute to sustainable nuclear medicine practice especially for patients with cancers.

  • 伊藤 拓
    2025 年22 巻2 号 p. 137-140
    発行日: 2025/07/31
    公開日: 2025/07/31
    ジャーナル 認証あり

    Medical radioisotopes (RI) are commercially manufactured with cyclotrons as raw material of radiopharmaceutical products. Nihon Medi-Physics, radiopharmaceutical company in Japan, has been developing manufacturing technology of alpha emitting nuclide 225Ac and positron emitting nuclide 89Zr for Theragnostic medical agent. For commercialization of RI, scaling up is required from basic study in academia (kBq–MBq) to commercial mass production (GBq–TBq). Gap of radio activity between them is over thousand times and overcoming of several technological challenges is necessary. Moreover, some other issue such as economic efficiency, quality requirements as medicine, regulatory also severely affect in commercialization. Described here is a part of topics from a speech in The Second Accelerator Symposium held on 12th December 2024.

  • 塚原 剛彦
    2025 年22 巻2 号 p. 141-146
    発行日: 2025/07/31
    公開日: 2025/07/31
    ジャーナル 認証あり

    The creation of sustainable nuclear and radiation technologies is expected to play an important role for the realization of GX (Green Transformation). Despite the expectation, many nuclear and radiation-related facilities in Japan are rapidly losing not only research and human resource development functions but also safety management systems due to the deterioration of facilities and instruments and the retirement of staffs. In order to solve the existing issues associated to safety management and to strengthen the research and education infrastructure, the conversion of nuclear fuel materials with no actual use into medical radioisotope resources should be one of the most effective strategies. Therefore, we are promoting an advanced project to construct a research and education platform enabling the centralized storage and management of nuclear materials, the securing of radium resources, and the actinium production.

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