日本歯周病学会会誌
Online ISSN : 1880-408X
Print ISSN : 0385-0110
ISSN-L : 0385-0110
19 巻, 4 号
選択された号の論文の16件中1~16を表示しています
  • 依藤 正
    1977 年 19 巻 4 号 p. 275-288
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    Gross and histological studies were made of gingival responses of multiple challenges due to long term administration of bovine serum albumin (BSA), in view of the findings that generally dental plaque markedly exists in human gingival sulcus resulting in various kinds of antigen acting on periodontal tissue.
    The results obtained were as follows:
    1. Macroscopical
    No changes were found in either Freund's complete adjuvant sensitized or nonsensitized rats.
    2. Histopathological
    In the sensitized rats infiltration of macrophages and lymphocytes was moderate early in gingival tissue. Little infiltration developed following long term multiple challenges of BSA.
    In the nonsensitized rats infiltration of macrophages was moderate in gingival tissue. But after sensitization it was almost absent following the same challenges.
    Therefore, when rats were sensitized with BSA, it was suggested that the defensive mechanism might act leading to no damage of tissue following long term multiple challenges of BSA.
  • 本間 博
    1977 年 19 巻 4 号 p. 289-302
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    The purpose of this study is to make clear the effect of long term occlusal trauma on the periodontal tissue in monkeys as compared with the result of the former short term experiment, in addition to observe the influence of occlusal trauma on progression of gingival inflammation to the underlying tissue.
    Two adult male Macaca irus monkeys were used. In order to create extra lateral force, cast gold high crowns extended mesially were set on mandibule left second molar (M2) and contra lateral tooth (2M) of each animal. The crown margin of M2 was ill-fitted, and was placed subgingivally to cause gingival inflammation, the other hand the crown margin of 2M was located coronally to the gingival crest to avoid marginal irritation.
    Oral examination was made every four weeks to check gingival condition, and standerdized radiographs were taken to investigate bone and periodontal space changes. Each animal was sacrificed after 12 and 24 weeks and tissue sections were prepared for histological examination.
    The results were as follows:
    1. Vertical bone resorption was observed radiographically in 8 and 12 weeks after giving extra lateral force using mesially extended high crown.
    2. Angular resorption of alveolar bone crest was also observed histologically, but apical-migration of junctional epithelium did not occured.
    3. Gingival inflammation was caused by ill-fitted crown which margin was placed subgingivally. However inflammatory cell infiltration always located coronally to the transseptal fiber though affected by occlusal trauma, and did not progress to the periodontal ligament area.
    4. From the result of the former short term experiment, it had been observed that periodontal tissue had been severely destructed in 4 weeks by occlusal trauma, but in this long term study the destructed tissue was partially repaired in about 16 weeks because of moving of the test teeth by excessive occlusal force.
  • 和田 甫
    1977 年 19 巻 4 号 p. 303-318
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    The mechanism of glucan-induced agglutination of Actinomyces viscosus was investigated using strain ATCC 15987 as a main test organism. A. viscosus cells attached only slightly to the uncoated enamel surface of extracted human premolars, whereas the cells markedly attached to the cement surface. The attachment of A. viscosus cells to the enamel surface was markedly enhanced by covering the surface with an artificial plaque consisting of cells and glucans of sucrose-grown Streptococcus mutans.
    This enhance attachment seemed to occur as a consequence of the agglutination of A. viscosus by the cell-associated glucan synthesized by S. mutans, because it was shown that a suspension of A. viscosus cells co-agglutinated with a suspension of sucrose-grown cells of S. mutans. The glucan agglutination of A. viscosus results from the binding of glucan molecules to a bacterial cell surface.
    This agglutination activity of A. viscosus was shown to be lost when the cells were either digested with trypsin or heated at 100 C for 10mm, suggesting the protein nature of a glucan receptor site. Among a variety of polysaccharides examined, only high molecular weight glucans containing α-1, 6 bonds as the main glycosidic linkage exhibited the activity to agglutinate A. viscosus cells. A study with chemically modified dextrans has revealed that C1-carboxylated dextran was active, but C6-carboxylated dextran was inactive in inducing agglutination of A. viscosus, indicating the importance of nonreducing ends of the glucan in its attachment to the receptor of the cells.
  • 発現頻度・位置・広がり
    川崎 孝一, 小林 なおみ, 大森 明, 原 耕二
    1977 年 19 巻 4 号 p. 319-332
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    A total of 67 (35 maxillae and 32 mandibles) Japanese (M. fuscata) and 74 (37 maxillae and 37 mandibles) crab-eating (M. irus) adult monkey jaws were examined for the incidence and distribution of alveolar bony defects (fenestration and dehiscence) because of the possible etiological factors for such defects.
    The following findings were obtained:
    1) Over three quarters (M. fuscata 83.3%, M. irus 80.0%) of the maxillary jaws examined showed one or more bony defects, with such defects more common in the maxillae than the mandibles (M. fuscata 33.3%, M. irus 14.3%).
    2) Incidence of these bony defects was higher in the posterior region than the anterior region.
    3) Fenestrations were more common in the maxillae (M. fuscata 76.7%, M. irus 77.1%) than the mandibles (M. fuscata 18.5%, M. irus 5.7%). The relatively high susceptibility of the maxillary first molars (42.0%, 47.3%) and first premolars (31.0%, 42.9%) to fenestration in Japanese and crab-eating monkeys was found in the present study. There was no difference in number of dehiscences between the maxillary and mandibular jaws. Dehiscences were found most frequently on the maxillary first molars and the mandibular third molars in Japanese monkeys and the mandibular third molars in crab-eating monkeys.
    4) Bony defects were predominantly found in the bimaxillary facial plate, with the exception of lingual plate in the maxillary first molars.
    5) Occurrence of fenestrations was commonly associated with root apex in the maxillae and coronal root in the mandibles.
    6) Examination of the data showed what appeared not to be a correlation between the occlusal wears and the bony defects.
    7) A congenital cortical osseous defect, a anatomic difference in the cortical plate density and thickness, a prominent root contour of the involved areas, a malalignment of teeth, a abnormality of buccal frenum attachment, a diet and a simply excessive traumatic force may be entertained as possible etiological factors of the bony defects.
  • 色川 俊則, 石田 悦保, 福岡 康裕, 米田 栄吉, 梁川 誠郎, 加藤 伊八, 砂田 今男
    1977 年 19 巻 4 号 p. 333-340
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    The changes of the periodontal tissues irritated mechanically by small active elastic rings on the survival portion of the right first molar were observed microscopically in germfree and conventional JCL: SD strain rats.
    The results obtained were as follows:
    1. Pocket formation, slight infiltration of inflammatory cells into the periodontal tissues and hyaline degeneration or disappearance of the gingival fibers in some degree were noticed in germfree rats.
    2. More sever inflammatory changes of the periodontal tissues such as epithelial acanthosis, ulceration, disappearance of the gingival fibers, wide spread inflammatory cell infiltration, alveolar bone destruction and abscess formation in the bifurcation of the teeth in conventional rats were distinctly recognized than in the germfree rats.
    3. The depth of the pockets in conventional rats was 0.8mm to 0.9mm and about twice of the depth in germfree rats.
  • その1. 冠辺縁の位置的違いと歯肉病変
    高山 文晴, 根津 雄一, 山田 みちこ, 山岸 茂, 渡辺 徹, 渡辺 安規, 高塚 真理子, 小林 なおみ, 原沢 正昭, 長谷川 満男 ...
    1977 年 19 巻 4 号 p. 341-357
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    This investigation was carried out to determine whether the cast gold crowns with different locations of the cervical margin cause or are associated with a marked difference in the periodontal conditions. The cervical position of each crown was built up according to the following system: 1) 1mm above, 2) even with and 3) 0.5mm below the gingival margin.
    Thirty-two teeth in 4 adult dogs were examined. The gingival state and oral hygiene were recorded according to the index systems (Löe, 1967). Pocket depths were calculated. The gingival exudate measurements had been also assessed using the orifice method (Egelberg et al, 1973).
    The animals were sacrificed at time intervals of 2, 4 and 16 weeks following the placement of the crowns. The blood vessel topography at the dento-gingival junction was studied, after perfusion with a carbon-gelatin mixture prior to the sacrifice (Egelberg, 1966). Bucco-lingual and horizontal serial sections 8 microns thick were made and stained with hematoxylin and eosin. The gingivae adjacent to the crowns were observed microscopically. The morphologic changes are described, based upon the clinical, the cellular inflammatory and the epithelial changes.
    The results indicate that in areas with crown margin below the gingival crest, more severe gingivitis was registered than in the another areas examined.
  • 平松 正彦, 畠山 桂子, 安部 勲, 南 直臣
    1977 年 19 巻 4 号 p. 358-363
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    The influence of diabetes on connective tissue components of gingiva was examined in the present study. Diabetes was induced by a single injection of alloxan monohydrate (80mg/kg, i.v.) in male white rabbits. Acid mucopolysaccharides (AMPS) and collagen contents and some of lysosomal enzyme activities of gingiva of diabetic rabbits were determined at different diabetic stage and these parameters were compared to those of gingiva of normal rabbits.
    1) AMPS content was decreased slightly at 1 week of diabetic stage, but increased at 6 weeks stage and significantly increased at 12 weeks stage in diabetic group as compared to normal.
    2) Salt soluble, acid soluble and insoluble collagen contents were decreased at all the stage in diabetic group as compared to normal.
    3) Mucopolysaccharase (β-glucuronidase, N-acetyl-β-glucosaminidase, β-glucosidase and β-galactosidase) activities were tendency to decrease at 3 and 6 weeks stage and acid protease activity was increased at 12 weeks stage in diabetic group as compared to normal.
  • IV. 酸性ムコ多糖の定量分析について
    三木 隆雄, 勝谷 芳文, 河合 淳二, 岩山 幸雄, 野村 慶雄, 石田 浩, 山上 紘志, 栢 豪洋
    1977 年 19 巻 4 号 p. 364-368
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    The constituents of acid mucopolysaccharides in the gingiva of patients with periodontal disease were studied using two dimensional electrophoresis on cellulose acetate strips. The result of electrophoresis indicated that the gingiva of patients with periodontal disease contained hyaluronic acid (HA), chondroitin sulphate A (Chs A), dermatan sulphate (DS), heparan sulphate (HS) and heparin (HP). And, the amounts of HA, Chs A, DS and HS were 32.3%, 22.7%, 40.1%, and 4.9% of the total acid mucopolysaccharides, respectively.
    Heparin was not found quantitatively.
    Careful comparison was made between the free gingiva as a severely diseased tissue and the attached gingiva as a least diseased one.
    It has been demonstrated that HA, Chs A in a higher level and DS in a lower level in the free gingival tissue in comparison with the attached gingival tissue.
  • 黄 景勝, 船川 芳洋, 大森 恒, 中静 正
    1977 年 19 巻 4 号 p. 369-374
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    The histamine contents in dental plaque collected from patients with periodontal disease were measured by Hakanson & Rönnberg method, and compared with various clinical findings such as simplified gingival index, debris index, calculus index, depth of periodontal pocket, degree of bone loss and teeth mobility.
    The following results were obtained;
    1. The histamine contents in detal plaque of all subject were able to measure in the range of concentration from 0.7 to 5.3μg/wet weight mg.
    2. The histamine contents in dental plaque had a tendency to increase according to the progression of simplified gingival index score.
    3. The histamine contents was decease with the increase of debris index score.
  • 第5報・各種歯肉包填剤の操作時間, 硬化時間, 硬さ, 液剤量について
    横山 邦生, 伊藤 真志, 矢谷 慎一郎, 本城 範典, 木村 智誠子, 橋本 光示, 下村 弘明, 山岡 昭
    1977 年 19 巻 4 号 p. 375-388
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    In vitro studies were made of periodontal dressing materials consisting of a eugenol group (Surgical pack [SHOWA], Neodyne pack, Periodontal pack) and a eugenolless group (Cello pack, Peripac, COE-pak).
    The examination included:
    9. Working times, 10. Setting times, 11. Hardness, and 12. Liquid quantity.
    The results obtained were as follows:
    1. Working times:
    The working times were required time in the following order;
    Periodontal pack, Cello pack, Neodyne pack, Surgical pack, COE-pak, Peripac.
    2. Setting times:
    The setting times were required time by method of Vicat's needle in the following order;
    COE-pak, Periodontal pack, Cello pack, Neodyne pack, Surgical pack.
    Peripac was similar to Cello pack.
    The initial setting times by method of Gilmore's needle was required time in the follwing order;
    Periodontal pack, Peripac, Neodyne pack, Surgical pack.
    COE-pak and Cello pack were similar to Surgical pack.
    The final setting times by method of Gilmore's needle was required time in the following order;
    Periodontal pack, Peripac, Cello pack, Neodyne pack, Surgical pack.
    No mesurment was possible to COE-pak.
    3. Hardness:
    The hardness was in the following order;
    Neodyne pack, Surgical pack, Cello pack, COE-pak.
    Peripac was similar to Neodyne pack.
    Periodontal pack was similar to Surgical pack.
    4. Liquid quantity:
    The liguid quantity was required in the following order:
    Periodontal pack, Surgical pack, Cello pack, Neodyne pack.
  • 第6報・操作時間, 硬化時間, 硬さについての知見補遺
    横山 邦生, 高田 耕平, 畠山 善行, 寺坂 章, 井上 庸三, 稲田 芳樹, 藤本 完次, 山岡 昭
    1977 年 19 巻 4 号 p. 389-393
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    In vitro studies were made of periodontal dressing materials (Septo-pack, COE-pak [Hard & Fast set]).
    9. Working times, 10. Setting times, 11. Hardness.
    The results obtained were as follows:
    1. Working times:
    The working times of Septo-pack was similar to Peripac.
    COE-pak [Hard & Fast set] was required about 20 seconds longer than COE-pak.
    2. Setting times:
    Septo-pack has finished the setting 2 to 5 times faster than Peripac.
    COE-pak [Hard & Fast set] have finished the setting faster than COE-pak.
    3. Hardness:
    Peripac was 10 times harder than Septo-pack. COE-pak [Hard & Fast set] was 2 to 3 times harder than CUE-pak.
  • 浦口 良治, 松尾 良平, 末田 武, 木下 四郎
    1977 年 19 巻 4 号 p. 394-398
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    Prevalence of grinding habit was studied on 539 students of a womens college, aged 18 to 21 years, and 85 dental students, aged 23 to 27 years. On the womens college students, examination of gingiva, eye, ear, nose and throat were also performed to know the relation with grinding habit. The results of this study were as follows: 54 womens college students (9.85%) and 19 dental students (22.35%) had grinding habit, and 71 womens college students (13.20%) and 7 dental students (8.20%) were suspected to have the habit. Any changes of gingiva, eye, ear, nose and throat were not significantly related to the existence of grinding habit.
  • 三木 隆雄, 勝谷 芳文, 河合 淳二, 岩山 幸雄, 野村 慶雄, 石田 浩, 福原 弘喜, 栢 豪洋, 岡田 充泰, 作田 守, 森崎 ...
    1977 年 19 巻 4 号 p. 399-406
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    Mucopolysaccharidosis is an autosomal recessively inherited storage disease, characterized by a clinical picture of dwarfism, grotesque facies, hepatosplenomegaly, joint contractures, corneal clouding, mental retardation, vascular and endocardial disease, and early death. Excess amounts of acid mucopolysaccharide accumulate in affected organs, and are excreted in the urine of patients with the disease. A 14 yearold boy who had been suffering from mucopolysaccharidosis with gingival hypertrophy, was observed. Acid mucopolysaccharides were isolated from his gingiva and urine, then investigated by chemical analysis and electrophoresis on cellulose acetate strips. The results of this experiment suggested that there may be some relation between periodontal disease and mucopolysaccharidosis.
  • 5年経過後の臨床的, 組織学的所見
    石川 烈, 渡辺 隆, 八幡 三郎, 遠藤 信武, 木下 四郎
    1977 年 19 巻 4 号 p. 407-412
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    Five years ago, an impacted third molar was transplanted into a second molar area of a patient aged 37 years old. During subsequent years, clinically the third molar replaced the second molar. Radiographic examination revealed normal bone surrounding the tooth root. Histological study showed thick secondary cement was newly formed and from the cement periodontal fibers were well established to form periodontal membrane space.
  • 木村 吉太郎, 佐藤 春海, 楠 正夫, 藤巻 伊佐夫, 渡邊 和仁, 片山 一郎, 金子 勝彦, 木下 四郎, 横田 誠, 浦口 良治, ...
    1977 年 19 巻 4 号 p. 413-430
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    It is wide recognized that the etiology of periodotal diseases is due to the local effects by the depositions at cervical region like dental plaque.
    In order to treat these diseases the removal of plaque and/or dental calculus by scaling and/or brushing, or the local application of anti-inflammatory agents are widely used. The anti-inflammatory agent —⌈XP-SN⌋— include Hinokitiol, Chlorhexidine, Glycyrrhetinic acid and dl-α-Tocopherol acetate as component.
    Redness, swelling, bleeding, pus discharge, depth of gingival pocket and movement of teeth were selected as indexes for clinical evaluation of periodontal diseases. The effect of tested agent was compared with placebo, and this study was conducted with double blind method.
    The results were summarized as follows:
    (1) Significant curings in redness, swelling, bleeding, pus discharge and depth of gingival pocket were recognized through this study no matter what agents were used. The curing level was more significant in gingivitis than periodontitis.
    (2) In the case of whole patients, there were significant difference in recovery of redness and swelling between ⌈XP-SN⌋ and placebo (p<0.01).
    (3) In the patients whose periodontal diseases were due to dental plaque and dental calculus, ⌈XP-SN⌋ was significantly more superior in the level and the time of recovery of redness (p<0.01), swelling (p<0.01) and pus discharge (p<0.05) than placebo.
    (4) The general improvement of ⌈XP-SN⌋ on periodontal diseases was more than 62 percent.
    (5) No particular side effect was observed through this study.
  • 松江 一郎, 清水 徹, 梅沢 良子, 小谷 朗, 下島 勲子, 酒井 文子, 朝倉 昭人, 沢村 文江, 栗原 恵子, 高島 巳千雄, 田 ...
    1977 年 19 巻 4 号 p. 431-446
    発行日: 1977/12/28
    公開日: 2010/07/16
    ジャーナル フリー
    Thirty one patients participated in this study. The effect of Chlorhexidine-Gluconate containing mouthwashes has been evaluated in two groups of thirty one patients during a period of 5 months.
    In the first group, L-S solution of Chlorhexidine-gluconate and Lactic Alminium and/or in the second group, placebo solution was used five times a day.
    It is suggested that inhibition of plaque and prevention of gingival inflammation may be controlled by daily mouthrinses of L-S solution of Chlorhexidine-gluconate and Lactic Aluminium compared with placebo solution, provided the agent is administrated in such a way that is reached all teeth surfaces.
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