A 62-year-old male diagnosed as AML showed a new complex translocation involving chromosomes 1, 8 and 21 in his marrow cells. The Q- and G-banding analyses interpreted the karyotype as 46, XY, 1q-, 8q-, 21q+, t (21; 8; 1) (q22 ;q22 ;q32).
The specific binding of 131I-rLH, 131I-rFSH and 131I-rPRL was compared between dissociated cells from intrasplenic tumorous grafts and those from heavily luteinized normal ovaries. The specific binding of both rLH and rFSH was much lower in tumorous graft cells than in ovarian cells but the binding capacity for rPRL was not different between the two types of cells. Dissociated cells of luteinized normal ovaries showed a gradual decrease in binding capacity for rLH with advancing age, but the binding capacity for rFSH and rPRL remained approximately the same.
Trisaccharide, having blood group H activity, was obtained from H substance. When the H-active trisaccharide was acted on by the enzyme (α-L-fucosidase) from Bac. Fulminans, fucose was liberated from it, thus losing its H activity and being reduced in the antigenicity common to Sh. dysenteriae, but retaining that common to D. pneumoniae Type XIV. The trisaccharide was split by the enzymes (α-L-fucosidase and β-D-galactosidase) from Bac. cereus H into the component sugars. When the enzyme (α-(1→2)-L-fucosidase) from Bac. fulminans was applied on a Leb-active oligosaccharide, fucose was liberated from it, and Leb-activity was lost to be replaced by Lea-activity. A weak Lea-active trisaccharide obtained from Lea substance was decomposed by the enzymes from Bac. cereus Lea into monosaccharides, fucose, galactose and N-acetylglucosamine.