Proceedings of the Japan Academy, Series B
Online ISSN : 1349-2896
Print ISSN : 0386-2208
ISSN-L : 0386-2208
Special Issue
Volume 74, Issue 3
Displaying 1-4 of 4 articles from this issue
  • Gi-Churl SHIN, Yoshibumi TOMODA
    1998 Volume 74 Issue 3 Pages 35-40
    Published: 1998
    Released on J-STAGE: October 17, 2006
    JOURNAL FREE ACCESS
    The Daiichi-Kashima seamount in the Japan trench and a wedge shaped seamount in the Ogasawara trench are good examples that the seamount breaks down and sink at the axis of the trench. We estimated subterranean structure of these seamounts using gravity anomaly and topography, and proposed a model. Disappearance of a deep root of the mountain in the upper mantle supporting the mass of the mountain, can explain the phenomena. It is suspected that main reason of disappearance of the root is due to compression caused by the bending of the plate near the trench.
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  • Yusuke KAWAKAMI, Norihisa KISHIMOTO
    1998 Volume 74 Issue 3 Pages 41-45
    Published: 1998
    Released on J-STAGE: October 17, 2006
    JOURNAL FREE ACCESS
    Synthesis of new disiloxane-containing polymers is described. New oxygen permeable membrane polymers and side-chain liquid crystalline polymers were synthesized by taking advantage of low rotational barrier energy around silicon-oxygen bond. Stereoregular poly[(methylphenylsilylene)trimethylene] and optically active poly[{(1S)-1-(1-naphthyl)-1-phenyl-3, 3-dimethyldisiloxan-1, 3-diyl}ethylene] were synthesized for the first time starting from optically active allylhydrosilane and optically active 1-vinyl-3-hydrodisiloxane, respectively.
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  • Synthesis of syndiotactic poly(vinyl alcohol)
    Kazunobu YAMADA, Tamaki NAKANO, Yoshio OKAMOTO
    1998 Volume 74 Issue 3 Pages 46-49
    Published: 1998
    Released on J-STAGE: October 17, 2006
    JOURNAL FREE ACCESS
    The free-radical polymerization of vinyl acetate (VAc) was carried out in various alcoholic solvents. Fluoroalcohols with a lower pKa and higher bulkiness were effective in enhancing the syndiotactic specificity of the polymerization. The polymerization of VAc in perfluoro-tert-butyl alcohol ((CF3)3COH) at -78°C led to a dyad syndiotacticity of 72%, which is the highest value reported for the radical polymerization of vinyl esters. Hydrogen-bonding between the acetyl groups of VAc and polymer and the fluoroalcohol molecule may be responsible for the enhancement of the syndiotactic specific propagation.
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  • Akira HAYASHI, Osamu DOI, Ichiro AZUMA, Kumao TOYOSHIMA
    1998 Volume 74 Issue 3 Pages 50-55
    Published: 1998
    Released on J-STAGE: October 17, 2006
    JOURNAL FREE ACCESS
    About 25 years ago, the study of cancer immunotherapy (IT) was done without paying due attention to patients' own immunogenicity, resulting in the failure in its clinical trials. This fact suggested that IT should be performed independently of other conventional chemo- and/or radiation therapies after removing as many tumor cells as possible. Between 1975 and 1997, total 235 cancer patients have been treated by IT with BCG-cell wall skeleton (CWS) alone, most just after surgical operations, and some after chemo- and/or radiation therapies. Appropriate dose (10 to 200μg) of BCG-CWS depending on the patients' biological responses, inoculated intracutaneously every 4 weeks, monitoring their immunogenicity with IFN-γ induction test. In this pilot study, clinical effect of the immuno-friendly use of BCG-CWS was shown most clearly in the effect of IFN-γ induction and cancer stages on the survival rate. In fact this therapy was really effective for various kinds of cancers and for the patients in Stage I-III, but not for those in Stage IV or in immunologically impaired state. Further in 84 postoperative primary lung cancer patients, especially in the group of 46 Stage III patients, the effect was statistically significant (χ2=8.546, p=0.0035). These clinical and statistical analyses suggest that the IT with BCG-CWS alone displays its effect on cancers attacking their lymphnode metastasis.
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