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Chikio HAYASHI
1954 Volume 30 Issue 2 Pages
61-65
Published: 1954
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(L'énumération transfinie. I)
Motokiti KONDÔ
1954 Volume 30 Issue 2 Pages
66-69
Published: 1954
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Kenjiro SHODA
1954 Volume 30 Issue 2 Pages
70-73
Published: 1954
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Tsuyoshi FUJIWARA
1954 Volume 30 Issue 2 Pages
74-79
Published: 1954
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Hidetaka TERASAKA
1954 Volume 30 Issue 2 Pages
80-84
Published: 1954
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Taira SHIROTA
1954 Volume 30 Issue 2 Pages
85-89
Published: 1954
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Zirö TAKEDA
1954 Volume 30 Issue 2 Pages
90-95
Published: 1954
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Takasi KANAZAWA, Akira IWASAKI, Haruo MURAKAMI
1954 Volume 30 Issue 2 Pages
96-97
Published: 1954
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Kôchi DOI, Kenzô NAGAI, Toshio SATÔ
1954 Volume 30 Issue 2 Pages
98-101
Published: 1954
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Eizo ASAMI
1954 Volume 30 Issue 2 Pages
102-105
Published: 1954
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Masao MINATO, Seiji HASHIMOTO
1954 Volume 30 Issue 2 Pages
106-108
Published: 1954
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Yoichi IITAKA
1954 Volume 30 Issue 2 Pages
109-112
Published: 1954
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Toshiro YAMADA, Isamu SHIIO, Fujio EGAMI
1954 Volume 30 Issue 2 Pages
113-115
Published: 1954
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Yasuo ABE, Tadatsugu HARUKAWA, Hisashi ISHIKAWA, Takuichi MIKI, Masao ...
1954 Volume 30 Issue 2 Pages
116-118
Published: 1954
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Yasuo ABE, Tjdatsugu HARUKAWA, Hisashi ISHIKAWA, Takuichi MIKI, Masao ...
1954 Volume 30 Issue 2 Pages
119-121
Published: 1954
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Yahito KOTAKE, Jun'ichi KAMADA
1954 Volume 30 Issue 2 Pages
122-127
Published: 1954
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1. Both the formation of xanthurenic acid and that of acetone bodies are closely correlated. Increased xanthurenic acid never fails to lead to increased acetone bodies and the converse holds good likewise. This fact is of no small interest and encourges us to further studies on diabetic symptoms of rats caused by xanthurenic acid.
2. It is also made clear here that both a proper quantity of anthranilic acid and pyridoxine are capable of remarkable holding in checking the formation of acetone bodies in rats.
We heartily thank Dr. Yashiro Kotake for his kind advices and encouragement, and also Dr. Takeo Sakan and Dr. Masao Yamaguchi for giving us synthetic xanthurenic acid.
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I. On β-Oxidation and Unsaturation of Cholic Acid by Actinomyces
Shohei HAYAKAWA
1954 Volume 30 Issue 2 Pages
128-132
Published: 1954
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1. Four strains of Actinomyces were isolated. They grew well and degradated bile acid extremely well in a synthetic culture medium in which the only source of carbon is free bile acid or the only source of carbon and nitrogen is glyco-cholic acid.
2. When cholic acid was used as a bile acid, Actinomyces No. 1164, which is one of the four strains, yielded two new acids with m.γ. 280-282° (decomp.) and with m.p. 248° (decomp.).
3. Acid with m.p. 280-282° (decomp.) is probably a derivative of bisnorcholenic acid, because it yields methyl dehydrobisnorcholate by the treatments of hydrogenation, methyl esterification and oxidation.
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II. Formation of Δ4, 9(11)-7-Hydroxy-3, 12-diketobisnorcholadienic Acid from Cholic Acid by Actinomyces
Shohei HAYAKAWA
1954 Volume 30 Issue 2 Pages
133-138
Published: 1954
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As described in a previous paper, the two new bile acids with m.p. 280-282° (decomp.) and 248° (decomp.) were obtained as the degradation products of cholic acid using Actinomyces No. 1164. The structure of the former, m.p. 280-282° (decomp.), is discussed and it is concluded that the acid possesses probably the structure of Δ
4, 9(11)7-hydroxy-3, 12-diketobisnorcholadienic acid.
Acknowledgement: The author expresses his hearty thanks to Prof. T. Shimizu for his interest and his encouragement on this study, to Dr. K. Hirayama for his help in measuring the ultraviolet absorption spectra and for his valuable criticism, to Dr. H. Kimoto for his help in determining the polarographs, and also to Mr. T. Oshima and Miss K. Nakatsuka for their help in culturing.
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III. Partial Synthesis of Methyl 7(α)-Acetoxy-3, 12-diketobisnorcholanate from Cholic Acid
Shohei HAYAKAWA
1954 Volume 30 Issue 2 Pages
139-142
Published: 1954
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1. Methyl 7(α)-acetoxy-3, 12-diketobisnorcholanate was prepared by a partial synthesis from cholic acid.
2. The new unsaturated acid of m.p. 280-282° (decomp.) obtained from cholic acid by Actinomyces was 7(α)-hydroxy-3, 12-diketobisnorcholadienic acid. This conclusion is based on the fact that the new acid yielded acetate of hydrogenated methyl ester which is identical with methyl 7(α)-acetoxy-3, 12-diketobisnorcholanate obtained from cholic acid.
3. The new acid gave two different hydrogenated methyl esters corresponding to methyl 7(α)-hydroxy-3, 12-diketobisnorcholanate, but the melting point of neither one was depressed below the original melting point of the methyl ester.
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Shoei ISEKI, Tatsuo SAKAI
1954 Volume 30 Issue 2 Pages
143-147
Published: 1954
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1. In S. anatum of subgroup E
1 of Salmonella E group occurs antigenic transformation when it is infected with lysogenic phage of S. newington of subgroup E
2. At the same time, in some of its cells the transduction of nutritional requirement, streptomycin resistance or maltose fermentation from E
2 is observed. In this case, only one factor can be transduced into one cell.
2. The cell into which is transduced one of the genetic properties can maintain this even when it loses its phage by the action of anti-phage antibody and thus has its antigen transformed. Consequently it is considered, as reported by Zinder and Lederberg, that the phage plays only the rôle of carrier of filtrable agent in the transduction.
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Yûsaku KOMATU, Han NISHIMIYA
1954 Volume 30 Issue 2 Pages
148-151
Published: 1954
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Yûsaku KOMATU, Han NISHIMIYA
1954 Volume 30 Issue 2 Pages
152-155
Published: 1954
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