順天堂医学
Online ISSN : 2188-2134
Print ISSN : 0022-6769
ISSN-L : 0022-6769
3 巻, 3 号
選択された号の論文の12件中1~12を表示しています
目次
原著
  • 第3編 実験感染例及び自然感染例における経過, 症状, 治療法等の研究
    田中 寛
    1957 年 3 巻 3 号 p. 155-162
    発行日: 1957年
    公開日: 2014/11/22
    ジャーナル フリー
    The present paper deals with the part of a series of the author's studies on Strongyloides stercoralis pertaining the clinical observations on human cases experimentally and naturally infected with the worms. An experimental infection was successfully made by applying about 300 infective larvae on the skin of the author himself. Peculiar, itchy erruptions occurred immediately after the application of the worms and lasted about 10 days, then gradually subsided until they almost disappeared after about 18 days, leaving localized pigmentations. Symptoms of the lung probably associated with the migration of the larvae appeared after 6 days and lasted for about 3 days, and the author was suffered from severe coughs during this period. Intestinal symptoms occurred from the 17 th day and intermittent diarrhea, constipations and abdominal pain was the chief complaints. The larvae were first detected in the stool on the 27 th day, and bloody mucous stools appeared from the 30 th day, associated with tenesmus. Accesses of coughs presumably caused by autoinfections of infective larvae reappeared from about 25th day. The experiments to cure the symptoms with “supatonin” (diethylcarbamazine drug originally used for filariasis) were made from the 39 th day and it was found out that the drug was dramatically effective in subsiding the abdominal symptoms. However, the radical cure of the disease could not be attaired by the drug since the larvae in the stools still remained positive in the course of the repeated treatments, 0.3g a day for various length of periods. Observations on the carriers of Strongyloides detected by the survey of intestinal parasites made at Amami Oshima Island were also made by the author. 37 cases with positive stool examinations were studied, and most of them were found to be in the chronical stage with intermittent acute symptoms. 6 cases were found to be almost symptomless, 16 with slight, 15 with medium degree of complaints. Experimental treatments with diethylcarbamazine by the dosis of 5 to 10 mg per Kg of body weight a day for two weeks were applied to 8 cases. In all of the cases, disappearance of the worm from stools could not be attained. In 6 cases with abdominal symptoms the drug was proved to ease the complaints. Gentian violet was also administrated to 3 cases and this was found to reduce the number of worms in the stools.
  • 松村 哲哉
    1957 年 3 巻 3 号 p. 163-168
    発行日: 1957年
    公開日: 2014/11/22
    ジャーナル フリー
    Die Untersuchung erstreckt sich auf das Studium der Blut- und Knochenmarksbilder Mäuse von reinem Stamm D.S.K., wobei der Befund mit dem am hybriden ermittelten in Vergleich gestellt wird. 1) Im weissen Blutbild des reinen Stammes sieht man, im Vergleich zu dem hybriden, eine leichtgradige Neutrophilie und daher eine relative Lymphopenie. 2) In Bezug auf die Zahl der kernhaltigen Zellen im Knochenmark gilt im grossen und ganzen dasselbe für den reinen Stamm wie für den hybriden. 3) Die Erythroblasten im Knochenmark des reinen Stammes sind an Zahl reicher als die des hybriden, dagegen handelt es sich um ein umgekehrtes Verhalten bei der Granulozytenzahl. 4) Bezüglich der Zellmorphologie im Knochenmark ist besonderes Augenmerk darauf zu richten, dass hierbei der Granulozytenkern sowohl die Segment- als auch die Ringform darstellt, wobei die letztere Form häufig die grosse Mehrzahl aller im Knochenmark vorhandenen Granulozyten beherrscht.
  • 渡辺 哲男
    1957 年 3 巻 3 号 p. 169-179
    発行日: 1957年
    公開日: 2014/11/22
    ジャーナル フリー
    1.Two cases of simple cysts of the kidney and two cases of polycystic disease of the kidney (one by necropsy and the other after operation) were reported. 2.The etiological factor of polycystic disease of the kidney is believed to be a hereditary disorder based on the failure of union of nephrons and collecting tubules during foetal stage. 3.From the findings indicating a transitional type between polycystic disease of the kidney, it is surmised that solitary cyst of the kidney (simple cysts of the kidney) with policystic disease of the kidney has a similar etiologic beginning and is a incomplete fusion of lesser degree.
  • 林 滋生, 原 淳, 平木 敬二, 高田 孰徳
    1957 年 3 巻 3 号 p. 180-186
    発行日: 1957年
    公開日: 2014/11/22
    ジャーナル フリー
    An epidemiological study using Scotch tape method, the perianal examination of eggs, together with interview of inhabitants was carried out at Sizuka Mura, one of the model sanitation villages in Saitama Prefecture, in August, 1956. In 46 persons out of 177 belonging 40 families examined, pinworm eggs were detected. No significant differences of positive rate in habitats, sexes, occupations, or incomes were observed. The positive rate observed in age groups, however, differed remarkably, i. e. age group 0 to 4 showed 11.8%, 51.7%, the highest rate becomes at the age group 5 to 9, and gradually declined toward age group more than 40 (8.9%). The tendency of familial aggregation of infections was very conspicious. No correlations were observed between the infection rates and the frequency of bathings or changing underwears. The only suspicious condition related to the rate was the space of the bed room, higher incidences were observed in the families lived in smaller spaces. The average number of the standard Tatami, Japanese Straw Mattless, per person in the bed room was 2.22 in the non-infected families, but 1.73 in the infected ones. A correlation was also seen between the rate in infection of mother and their children, but was not significant between fathers and their children. There was observed very high relation between the incidence in husbands and that in their wives. From epidemiological observations mentioned above, it was concluded that the infection of pinworms may cause by the contact in wider sease among various factors.
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順天堂大学創立10周年記念講演
順天堂医学会例会抄録
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