Juntendo Medical Journal
Online ISSN : 2188-2134
Print ISSN : 0022-6769
ISSN-L : 0022-6769
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Volume 31, Issue 3
Displaying 1-14 of 14 articles from this issue
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Contents
  • 猫右室乳頭筋におけるノルエピネフリンの用量·作用曲線に対するPancuronium, Vecuroniumの影響
    MASAHARU SHIRAISHI
    1985 Volume 31 Issue 3 Pages 381-387
    Published: September 10, 1985
    Released on J-STAGE: November 20, 2014
    DOIhttps://doi.org/10.14789/pjmj.31.381
    JOURNAL FREE ACCESS
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    Norepinephrine (NE) dose-response curves in the contractile force and its max dF/dt were examined in the papillary muscle of the right ventricle of the cat under pretreatment with pancuronium bromide (PB), 3 X 10-5M. and vecuronium bromide (VB), 3 X 10-5M., 10-7M.. The dose-response curves with PB pretreatment were shifted leftward significantly as compared with the control group. The curves under pretreatment with VB were also moved to the left the same as those with PB pretreatment. It is likely that the shift to the left by pretreatment with PB may be due to the inhibition of NE uptake 1 and that by pretreatment with VB to the inhibition of NE uptake 2.
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  • Echocardiographic Study on Ischemic Heart Disease Masquerading as Dilated Cardiomyopathy
    TADASHI FUJIWARA
    1985 Volume 31 Issue 3 Pages 388-401
    Published: September 10, 1985
    Released on J-STAGE: November 20, 2014
    DOIhttps://doi.org/10.14789/pjmj.31.388
    JOURNAL FREE ACCESS
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    The purpose of this study was to determine whether two-dimensional echocardiography (TDE) can differentiate ischemic heart disease (IHD) from dilated cardiomyopathy (DCM) The subjects consisted of six patients with IHD (Group I) who showed left ventricular dilatation and diffuse abnormality of wall motion, but did not manifest obvious localized myocardial infarction or left ventricular aneurysm on TDE, and 26 patients with DCM, postmyocarditic cardiomegaly and alcoholic heart disease (Group II). A short-axis image of the left ventricle obtained by TDE at the chordal and the papillary muscle levels was divided into four quadrants. Regional wall motion abnormality (asynergy) with reference to systolic thickening was analyzed qualitatively in each segment. It was studied whether the anterior or posterior two segments showed discordance in grade of asynergy (discordance) at each level. A pathological study was also performed on five autopsied hearts in order to compare the grade of asynergy with the severity of myocardial degeneration and fibrosis in the same segment. The results were as follows : 1) M-mode echocardiography : The mean LVDd showed no significant difference between the two groups. Eight patients in group II showed marked left ventricular dilatation (LVDd≥ 75 mm), but there were no such cases in group I. 2) Regional wall motion : Five group I patients showed discordance in the posterior two segments, while in group II, only one case out of all those with mild left ventricular dilatation, who had received a ventricular pacemaker implant, showed discordance in the anterior and posterior two segments. Six of the patients with marked left ventricular dilatation showed discordance in the anterior or posterior two segments. No group I patient showed discordance in both sides. 3) The pathological study : In one patient in group I, the severity of myocardial degeneration and fibrosis was well correlated with the grade of asynergy, but in three group II cases except one case there was no correlation between these two findings.
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  • The Usefulness and Limitations of Xeroradiography in the Diagnosis of Bone Diseases
    FUMIHIKO TAMAMOTO, HITOSHI KATAYAMA, YUTAKA NAOI, MASARU SUZUKI
    1985 Volume 31 Issue 3 Pages 402-415
    Published: September 10, 1985
    Released on J-STAGE: November 20, 2014
    DOIhttps://doi.org/10.14789/pjmj.31.402
    JOURNAL FREE ACCESS
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    Xeroradiography is one of the imaging modalities using electrostatic techniques. The images of Xeroradiograms are characterized by wide latitude and edge-enhancement effect. Xeroradiography is used for diagnosis of diseases in several fields, but the evaluation of the usefulness in diagnosis of bone diseases has not been clearly established. In this study, the differences between Xeroradiography and roentgenographic images were reviewed using bone phantom. And comparative study of each abnormal finding demonstrated by the Xeroradiograms and roentgenograms in 26 clinical cases was performed from the standpoint of capability of diagnostic imagings. The eight abnormal changes we evaluated were 1) periosteal reaction, 2) destruction of cortices, 3) radiolucent lesions, 4) osteosclerosis, 5) internal structure of the lesions, 6) marginal sclerosis, 7) intraosseous calcification, 8) soft tissue abnormality or relationships between the lesion and surrounding soft tissue. The usefulness of Xeroradiography for the diagnosis of periosteal abnormalities, such as periosteal reaction and surrounding soft tissue abnormalities, was reconfirmed. And the advantage of Xeroradiography for the diagnosis of lesions associated with osteosclerosis, thickening of cortices and large mass was clearly proved, but its disadvantage for the diagnosis of changes in bone density, such as radiolucent and osteosclerotic lesions, was also demonstrated.
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  • Investigation of Mass Screening for Congenital Biliary Atresia Using the Dried Urine Spot (That is Maild in)
    HIROSHI NITTONO, TOYOHIKO WATANABE, HIDEKUNI SASAKI, NORIKO NAKATSU, K ...
    1985 Volume 31 Issue 3 Pages 416-421
    Published: September 10, 1985
    Released on J-STAGE: November 20, 2014
    DOIhttps://doi.org/10.14789/pjmj.31.416
    JOURNAL FREE ACCESS
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    To examine the system by mail in the mass screening for congenital biliary atresia (CBA) using the dried urine spot (DUS), bilirubin in the DUS of the about one-month-old babies was measured by (the Harrison spot) test. The results were as follows. 1. DUS samples sent back between April 1, 1984 and May 14, 1985 totalled 983, and the rate of withdrawal was 54.3%. 2. Cases reported as jaundice (+) totalled 78 (7.9%). 3. Those reported as gray stool (+) (Acholic stool) accounted for 18 (1.8%). All these samples represented errors in reporting. 4. The positive reaction of bilirubin in the DUS was recognized in only one sample of stool mixed with urine. The other 982 showed the negative reaction. 5. The time elapsed before the DUS was sent back to the our institution after urine blotting in 100 cases was from one to 12 days. The average of this period was 3.85 days. The Harrison test for the detection of bilirubin in the DUS is cheap, simple and safe and facilitates detection of bilirubinemia in the baby with CBA. However, it is necessary to shorten the period between urine blotting and sending back the DUS. This method may be useful for screening for cholestatic diseases at one-month well-baby clinics, too.
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