順天堂医学
Online ISSN : 2188-2134
Print ISSN : 0022-6769
ISSN-L : 0022-6769
7 巻, 2 号
選択された号の論文の18件中1~18を表示しています
目次
原著
  • (特に電顯像について)
    渡辺 茂
    1961 年 7 巻 2 号 p. 147-160
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    Rheumatism is a leading one of collagen diseases, causes diffuse damages in the connective tissue, and is often complicated with cardiac diseases. Biopsy was applied to knee-joints affected with rheumatic diseases, i. e. rheumatic fever, rheumatic heart diseases and rehumatoid arthritis, 50 cases in all. The tissues of knee-joints were studied with optical microscope, in particular, with electron microscope, in many stadia of rheumatism diagnosed by serum reaction which determines its rheumatic activity. By these experiments, (1) various abnormalities were found in synovial membrane and blood vessels in parallel with many stadia in rheumatic activity. (2) Vascular change of peculia_??_ irreversibility was shown in the final stage of rheumatism. (3) The pathological findings of collagen fiber were found in the connective tissue. (4) The relationships between the findings of electron microscopy and those of optical microscopy are of much innterest in the study of rheumatism.
  • 杉山 邦夫
    1961 年 7 巻 2 号 p. 161-176
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    Owing to the introduction of the new sterilization theory of bacteria by Ball and Olson etc. in recent years, the method of heat-resistance of bacteria by the previously employed qualitative method now has come to be re-examined. The author undertook several experimental studies on the above thesis by the quantitative method especially by the calculation of thermal death time, and obtained the following results. 1) The living cell of Escherichia coli reduced logarithmically according to the law of monomolecular reaction equation, and the heating with the pre-heating period accelerated the reduction of living cells. 2)No difference in the heat-resistance was recognized between the strain cultured in broth and that in milk when the same number of cells were used. 3)Sucrose and gelatin strengthened the heat-resistance of Escherichia coli, however, no changes in the thermal death time of this strain was recognized in case when living or dead cells of other bacteria were present in the number of cells used in this study. 4)Comparison was made between Escherichia coli after 145 successive daily transfers at 25°C and those at 37°C, and, no difference was recognized. According to the above experiment undertaken with a new standpoint of view, new findings were added to the heat-resistance of Eschrichia coli.
  • 小林 安春
    1961 年 7 巻 2 号 p. 177-181
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    The relations between the distemper and the measles have been discussed for years and it is said that the fixed germ of the distemper and that germ of the measles have the common antisubstance. Inoculating the pure line baby mice's brain with the canine distemper virus, the author studied their peripheral blood picturis and bone marrow pictures, comparing those of the mice which caught the measles. (1)In the peripheral blood, in the period of the attack of the disease, a slight decrease in number of erythrocytes and that in quantity of hemogrobins were observed. The total number of leucocytes, lymphosytes, and neutrophil cells decreased and they shifted toward the left of the nuclei. The other cells showed a tendency to increase. (2)In the bone marrow pictures, the number of nucleated cells decreased and at the same time erythroblast cells and neutrophil cells decreased. Lymphocytes die not change clearly themselves and all the other cells showed a tendency to increase. (3)Comparing the blood pictures and the bone marrow pictures of the mice inoculated with the canine distemper virus with those that caught the measles, the total number of leucocytes and the number of nucleated cells in the bone marrow decreased in the former, but increased in the latter. The other changes through the course were almost the same.
  • 小林 安春
    1961 年 7 巻 2 号 p. 182-186
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    Inoculating the pure line baby mice's brain with varicella virus, the author studied their peripheral blood pictures and bone marrow pictures. The results of the experiments were as follows. (1)In the peripheral blood, there was no change in the number of erythrocytes in the peroid of the attack of the disease but hemogrobins decreased a little in quantity, the total number of leucocytes decreased, lymphocytes and neutrophil cells decreased in the absolute value, neutrophil cells shifted toward the left of the nuclei and eosinophil cells decreased or vanished. Monocytes cells increased from the latter period of the attack of the disease till the period of the recovery. Plasma cells did not change themselves and reticulum cells appeared in a few numbers. (2)In the bone marrow pictures, the number of nucleated cells decreased remarkably as well as erythroblast cells and neutrophil cells in the period of the attack of the disease. No. changes were observed in the eosinophil cells. Lymphosytes increased in the period of incubation. The increase in number of monocytes, plasma cells and reticulum cells was observed. Both erythroblast cells and leucocytes showing the nuclear fission pictures increased.
  • 十念 一浩
    1961 年 7 巻 2 号 p. 187-194
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    I carried on the experiments with white rats in order to test clinic overvations, numbers and phagocytosis of leucocytes, and sterilizing power of the blood at hypervitaminosis of A, K, D and E. I came to these conclusion. 1) In these hypervitaminosis, the phagocytosis rate of neutrophile leucocytes declined, however, there were some difference of period or extent on each hypervitaminosis. On lymphocytes, there were not celebrated alternation of the phagocytosis rate. 2) Curves of the alternation of leucocytes numbers were nearly parallel to the phagocytosis rate of neutrophile leucocytes, expect some distorsion. 3) To infection of the bacterium, the resisting power of white rats decreased at hypervitaminosis.
  • 第1編 ブドウ球菌に対する各種抗生物質の併用効果
    森 邦義
    1961 年 7 巻 2 号 p. 195-199
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    In vitro inhibitory effect of chloramphenicol, oleandomycin, neomycin neomycin and kanamycin to the newly isolated 30 strains of staphyloccoci was investigated. Experments were carried out by the combination of two antibiotics of them in various concentrations using liquid media and both bacteriostatic and bactericidal action of them were observed. The combined effects were seen every combinations for 30 to 50% of the test strains. Specially effective combination was not found. In some cases, combined effects were changed by time, and sometimes bacteriostatic action and bactericidal action of the same combination was not parallel.
  • 羽木 穣
    1961 年 7 巻 2 号 p. 200-226
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    In these studies several amino acids solutions of various composition were used before and after surgical operations, in order to see their effects on the values of free amino acids in blood plasma and urine of the patients transfused with mixed crystalline amino acids. Farther, the effects of plasma expander used jointly with crystalline amino acids, and the differences between the results of the transfusion of crystalline amino acids and that of the transfusion of stored blood were studied. The results were as follows : 1) Immediately after the transfusion of crystalline amino acids solution into the patients, there was no proportional relation perceived between the values of each free amino acids in blood plasma and urine of the patients and the quantity of each crystalline amino acids transfused. 2) The increased total value of free amino acids in blood plasma and urine decreased gradually, but the value in blood plasma after three hours was higher than that of after an hour. 3) The total value of free amino acids in blood plasma increased remarkably before operation, but a notable increase of that in urine was clearly witnessed after operation. The increase of Threonine and Proline was marked before operation, while that of Threonine, Proline and Glycine was distinctly observed after operation. 4) The values of free amino acids in blood plasma and urine were not parallel with that of transfused solutions of each kind. The difference of composition ratio of those solutions disturbed the free amino acids pattern in blood plasma and urine. 5) The values of free amino acids in blood plasma and urine of the patients suffering from cancer and ulcer of stomach were increased more in contrast with those of the patients of other diseases ; when crystalline amino acids solutions were transfused into the patients, the values of free amino acids of gastric cancer were the highest, and those of the contrast group were the lowest. 6) The utilization rate of the amino acids showed about 90% before operation, but 77.6-63% after operation. In accordance with the variance of composition, it showed the difference of 11-13%. 7) By applying P. V. P. with crystalline amino acids, a slight increase of amino acids was seen remaining in blood, and when these two were used in succession, the utilization rate of the amino acids was considerably down on the fifth day before and afteb operation. 8) The transfusion of crystalline amino acids solution showed a similar alteration of the total value of free amino acids with that of stored blood with the lapse of days. The total value of free amino acids in stored blood transfusion increased remarkably in urine before operation and in blood plasma after operation, and these results showed just a contrary phenomenon to it in crystalline amino acids transfusion.
  • --都内某鉛筆製造工場の事例を中心として--
    松田 善雄
    1961 年 7 巻 2 号 p. 227-253
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    The author has analysed the actual state of pencil factory and has observed health control measures grasping health condition of workers in such a environment etc. Through the results, this paper is devoted to study health control measures in medium and small enterises including noxious ones in their works in general. The observations were as follows. 1. As it was considered that noxious works were carried out not only in the place of so-called noxious works but also in its snrroundings, it was necessary to control health of all the personnel working in the noxious places including its surroundings in medium and small enterprises. 2. As sanitary control, it was necessary to improve it in compliance with the actual condition of medium and small enterprises from the economical point of view, and the betterment should be gradually carried out in such enterprises. 3. It was very important to try to find patients as possible as early from side of persons. As it was very difficult to control sanitary conditions perfectly and there were many causes to remain for outbreak of patients, early detection of patients was more important. 4. It was admitted that surveys of subjective symptoms including the best of Cornell Medical Index and inquiry of gastroenteric diseases were effective as screening methods of patients. It was observed that the examinations of health hazards which essentially combined with noxious conditions were necessary in the place of noxious works. For example, it was necessary to carry out blood examination about every six months in the places such as in pencil factory, where benzol poisoning was possible to occur. It was recognized GB, Hb, the numbers of erythrocytes and leucocytes in blood were especially important indexes and examination of urobilinogen in urine was comparatively effective method in such enterprises.
  • 昼間 善継
    1961 年 7 巻 2 号 p. 254-265
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    As one of the influences of submarine of Snorkel type upon human body, the author has investigated the influence of intermittently variable pressure, which had been burdened to decrease and to recover over again. By opening and closing of the head valve of Snorkel, pressure decreaced to 586mmHg and cardio-pulmonary function and blood were examined in raddits and rats. About human body, blood etc were examined in a little higher pressure than 586mmHg. Then the examined group had been divided into two grous, an hour group and two hour group, according to the duration of burdening. The results were as follows. I. Animal 1. The tendency of increasing in the weight was appearee after 8 days after finishing the burdening.None had increased in the weight during those burdening period. 2. As the view of blood, it was admitted that the number of erythrocytes gradually slightey increased, and the number of leucscytes, the quantity of hemoglobin and the number of eosinophile cells gradually decreased after the burdening. It was observed from the reselts that the burdening acted as rather strong stress for bodies. 3. From the result of the measuring oxygen saturation by Oximeter in peripheral artery, 2 cases showed middle grade of hypoxaemia and another 2 cases showed arhythmia in E. K. G. during the bardenig. Health diagnssis concerning cardio-pulmonary function seemed to be especially necessary at the time of such burdening. 4. From the obduction, swelling of suprarenal body, especially of pulp, was admitted. II. Human body About the examination of human body, the view of blood was almost as same as in the cases of animall and it was expected that repeated variation of air pressure acted as comparatively strong stress for human bodies even if the air pressure was rather low (ex. coressponing to 1500m).
  • 李 夏栄, 裴 憲
    1961 年 7 巻 2 号 p. 266-269
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    Audiography using 4000 cycle was carried out to 490 coalminers. In 41% of the miners, slight hearing disturbance was observed. The percentages were difierent by the working position ranging from 60% to 35% and the continuity of the occupation was the longer, the rate of the incidence was the higher. Especially, in the cases continued the occupation for over 4 years, the fact was remarkable. The audiogram of the cases was about 10db at 2,000 cycle and about 30db at 4,000 and 8,000 cycle.Hearing capacity of them in normal speaking area had not been disturbed.
  • --病巣近傍部の前後屈運動のレ線学的研究--
    高橋 純, 松村 利雄
    1961 年 7 巻 2 号 p. 270-280
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    The range of moument of the spine with tuberculous spondylitis has been studied on lateral roentgenograms. Three ruoentgen photographs were taken in different postures for each patients : (1)kept standing reluxed, (2)maximally flexed, and (3)maximally backward flexed. On the first roentgenograms angles made by destruction of vertebral bodies, extent of the compensatory lordosis and its localisation were studied. Compsring the second and the third roentgenograms, the range of movement of each vertebral body was examined. At the level of the involved vertebrae no measurable movement was found. Betwwen. the not involved vertebral bodies, marked limitation of movement was observed, and there were some patterns of the limitation according to the localisation of tuberculous involvement.
  • 藤井 滋
    1961 年 7 巻 2 号 p. 281-304
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    As to the treatment of periosteal callus in the fracture, out of clinical cases 50 ones administered non-bloody and bloody operation respectively, totalling 100 ones, were chosen and mainly observed from the roentgenographical point of view in the Ist Section, while calluses formed in the periosteum conser ved region and the periosteum removed region of experimental fracture in mature rabbits were observed by the microradiography in the 2 nd Section. Results thus obtained are as follows. (1)Cases administered non-bloody treatment have not only a better periosteal callus formed from the roentgenographical standpoint, but also cause the union of fracture at earlier date than those administered bloody treatment. (2)The periosteal callus is greatly influenced by the detachment, laceration and crush of periosteum owing to the primary and secondary injury. In other words, the callus is unlikely to be formed in cases presumed to be remarkably injured in the periosteum in view of the dislocation, or in regions given operative impetuses. In these cases the reduction in the reproductivity of periosteum owing to the periosteal injury is presumed to be responsible for delay of the therapy. (3)The experiment demonstrates that the callus is formed more quickly and more quantitatively in the periosteum conserved region than in the periosteum removed region. (4)The more approximate to the normal periosteum as well as to the detached and swollen periosteum a new bone is, the more compact it becomes and the more distribution of salt of lime it contains, thereby suggesting the reproductivity of periosteum. (5)The progress of calcification is concluded from the increase in salt of lime in the callus, and indicates clearly the weekly course of osteogenesis. (6)The salt of lime is also distributed in the cartilage layer of callus. (7)It ensues that the recovery of fracture in juveniles is recognized to coincide with the period of its union indicated by Gurlt, but in adults requires 1.5-3 times the period.
  • 李 夏栄
    1961 年 7 巻 2 号 p. 305-315
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    Circulating eosinophil cells were counted in many different conditions and their physiological significance was discussed. Expeiments were performed by Fuchs-Rosenthal's counting chamber and at least 4 times of tests were necessary for one specimen. Physiological changes of the cell levels were relatively great and rythmical, i.e. in general, they were high in day time and low in night. In the cases of new-borne, whose mother suffered with parasites, the eosinophil cell levels were high. The levels decreased by the working stimulus and in fatigue state, the levels were retained unchanged or more decreased. In the cases of sever muscular working, the cells icreased, once, and then decreased. This phenomenon was considered to be caused by the temporary decrease of the corticoid in blood stream. The otherhands, in the cases of the mental work, in which corticoid decrease in the blood did not occur, the cells decreased at onces.
  • 李 夏栄
    1961 年 7 巻 2 号 p. 316-318
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    A case of the progressive musclar dystrophy was reported. Patient was 9 years old male, suffering for 5 years. with this disease. Musclar dystrophy was seen at breast and legs and deep tendon reflex was weakened. remarkablly.
  • 木内 立三
    1961 年 7 巻 2 号 p. 319-323
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    1, The author was able to find the degeneration of the cells of Nucl- motorius n. torigemini, Nuclloci caerulei and Nucl. mesencephalicus n.trigemini of the rat after removal of N. nasseter, so it can be say that the origin of N. masseter is above three nucleus. 2. N. loci cacrulei, its function is not yet clearly determinded, has the relation between the N. masseter, one branch of the N. trigemini and is sensibel. 3. The light degeneration of the cells of the Nucl. mesencephalicus n. trigemini can be found after removal of the N. masseter of the rat, so this nucleus is sensibel.
  • 松浦 寛忠
    1961 年 7 巻 2 号 p. 324-329
    発行日: 1961/04/10
    公開日: 2014/11/22
    ジャーナル フリー
    The author found the changes of the blood of the rat, especially the leucocyt, after removal of N.facialis and N. masster. 1 The leucocytosis. lymphopenie and neutrocytosis, can be found after five hours of the removal of N. facialis. 2. The light leuolcytosis can be found after removal of N. masseter, 3. The heavy leucocytosis, neutrodytosis and lymphopenie, can be found after removal of the N. facialis and N. masseter. 4. The nucl. loci caerulei is the origin of the N. masseter, so this nucleus may have the relation between the leucocyte.
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