Now, extracorporeal circulation is performed as a treatment of severe cardiac hypofunction. However, extracorporeal circulation with artificial heart lung apparatus cannot output pulsatile flow that heart makes it intrinsically. In this research, we suggest a system that keeping pulsatile flow when a pulsatile flow-generating circulatory-assist device is used in extracorporeal circulation. This report refers to the developed monitoring system that is able to display control conditions, electrocardiogram and parameters from the pulsatile flow-generating circulatory assist device.

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The final purpose of this research is to develop a painless microneedle which is mimicking the size of female mosquito′s labium to mitigate pain for diabetic patients. However, the decreasing of outer diameter will affect inner diameter, rigidity and pressure in inner tube. The inner diameter and the rigidity of the needle will decrease while pressure loss will increase. In order to design painless microneedle which fulfilled painless, high-rigid and low-pressure loss, we need a pain evaluation test to determine the marginal outer diameter size of microneedle. Here, a pain evaluation test through stress assessment test has been proposed. However, this pain evaluation test is not a direct method to evaluate pain. In this study, we focused on Substance P (SP), which is one of pain transmitter. The SP has been proven expressed only at the stimulated region after simulated mouse skin with both chemical irritation and physical irritation. Therefore, we conducted an experiment by injected mouse skin with various diameter sizes of needle and determine the best diameter size by calculating the quantity of expressed SP by using image processing.

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Enzyme Linked Immunosorbent Assay (ELISA) is necessary for a next generation safety and healty society to be expected as a metrology for grasp of previous disease. We have developed the technology of µL droplet stirring using a high voltage electric field, so called electric field noncontact stirring technology (E.N.S). It became possible that the processing time shorten within 30 minutes using E.N.S for ELISA.

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Zr based bulk metallic glass alloy has promising mechanical properties for MEMS applications although it has received little attention as a micro-material. We have tried to explore an optimum composition of ZrNiAl alloy film for stable amorphous phase using the combinatorial sputtering method. Crystallization temperature evaluation of the sample libraries depoited by triple source sputtering showed that the alloy films having a composition of around Zr40Ni30Al30 were very stable amorphous material of which crystallization temperature were higher than 550C.

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We have tried to fabricate the BN films containing cubic phase using rf magnetron sputtering. In this work, we have mainly studied the effect of substrate bias voltage on the growth of c-BN films. It was found that the films containing c-BN phase can be grown when a substrate bias voltage higher than 80V is applied. The fraction of the c-BN phase in deposited films increased at higher substrate temperature and/or lower working gas pressure.

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The demand of more accurate and durable edge shape has increased for high-performance cutlery and medical operation tools. In a plasma nitriding, high density ion can be obtained efficiently by installing a hollow cathode, and the samples can be cleaned, etched, heated and nitrided effectively, which would lead to the decrease in the sample damage. In this study, the cutting performance and the durability of stainless steel razor blade treated by the plasma nitriding were investigated in order to evaluate the applicability of plasma nitriding to the surface treatment of the edge shapes. Experimental results clarified that the edge shape was not changed by the plasma nitriding when the processing temperature was less than 543K, which kept its high cutting performance. Also, the durability of the blade could be improved by the plasma nitriding.

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This paper discusses the basic characteristics and the precise efficiency of washing on the surface of precision instrument of ER water (electrolyzed reducing water) of dilute Na2SO4. First, the structure and the characteristics of electrolyzed reducing water producing system as well as how electrolyzed reducing water of dilute Na2SO4 is produced by it are described. Next, the relation between the characteristic value of Na2SO4 ER water and the value of electrolyzed electrolytic-current, and its difference from Na2SO4 ER water, NaCl ER water and NaOH solution are investigated experimentally. Lastly, based on the result of washing on the surface of precision parts by Na2SO4 ER water, C9H12 solution and pure water, the washing efficiency of Na2SO4 ER water is verified.

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In this study, we have designed a droplet generation device by using ultrasonic torsional vibration which is applicable to high viscosity liquids. We have generated droplets in the air by using water and silicone oil, and realized droplets which had small and uniform diameters. In addition, we have evaluated condition of driving frequency and dispersal rate of droplets when we generated droplets.

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We developed tube type micropump which is the integration of flow part and pump part. However, flow rate of the micropump is extremely small. Thus, it is necessary to improve fluid performance by increasing deformation amount of PZT actuator. The increasing deformation amount of PZT by adding rectangle trenches is confirmed under FEM analysis. However, according to Static-piezoelectric-analysis, the stress concentration occurs at the trench part. Therefore, we search for the optimum trench shape which can scatter the stresses while maintain the deformation amount of PZT by static-Piezoelectric-analysis. We focused on (a) existing rectangle trench, (b) trapezoid trench, (c) curvature trench and they were analyzed. As a result, the reduction of equivalent stress is confirmed by changing trench shape. Therefore, deformation amount of PZT was decreased by changing trench shape.

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Recently, many types of soft actuators were developed using electro conducting polymers. In this study, we proposed the flexible actuators driven by an electro-heating. The fabricated actuator was composed of an electro-heat device, a modified shape memory alloy (SMA) fiber and electrodes. The modified SMA fiber can be contracted by heating and act as an artificial muscle. Two types of heating devices were tried based of particulate filled composites. One is a Joule heating device and another is a dielectric heating device. The driving characteristics of the heating devices were experimentally investigated. It is confirmed that the actuators can act by the proposed systems, still the bending displacement is a few mm to the 50mm length.

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In recent decades, planar panels and semiconductor wafers have increased in size in order to raise the productive efficiency. However, the substrates become breakable with enlarging because the thickness does not change even though the area gradually grows, and therefore the panels and the wafers bend more easily. The conventional transportation method of the contact type with a roller and a palette can cause some problems due to contact with the substrate. Therefore, these manufacturing processes demand a higher level of quality control to increase yield rate. To solve these problems, we propose a handling mechanism to transport substrates without any mechanical contact.

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A bolt-clamped Langevin-type transducer for ultralow temperature environment using PMN-PT single crystal has been fabricated and evaluated. Generally, piezoelectric materials have low piezoelectricity at ultralow temperature. PMN-PT has larger piezoelectricity than PZT at low temperature. The vibration performance of PMN-PT single crystal was evaluated at ultralow temperature. Additionally, we have evaluated a bolt-clamped Langevin-type transducer using PMN-PT single crystal in ultralow temperature environment.

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Pulse-driven capsule robot could actively move on a smooth ground. However, there is a big problem. It can not climb over a different level of terrain even through the height of terrain is just 0.3 mm at 3 volts. It is due to the principle of pulse-driven motion. The capsule robot has to move back and forth for translation. In the case of elastic collision, there are a backward motion and a reaction force after the collision. This can cause un-climbable or stuck condition. For this reason, we improve the capsule robot motion by using three steps from four steps of motion. It can decrease the backward motion force and make more smooth motion. This technique uses microcontroller to modulate the pulse width for inducing the coil. The result indicated that the capsule robot can climb over a low level of terrain by this method.

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Some micro mechanical parts utilized extra fine wires are developed. Making processes and performances for a micro-screw, a micro-nut, a micro helical gears, a micro spiral bevel gear, an axial flow micro-turbine are described in this paper.

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