RADIOISOTOPES
Online ISSN : 1884-4111
Print ISSN : 0033-8303
ISSN-L : 0033-8303
Volume 18 , Issue 5
Showing 1-6 articles out of 6 articles from the selected issue
  • Tokan RAI, Mutsuaki SHINAGAWA
    1969 Volume 18 Issue 5 Pages 171-174
    Published: May 15, 1969
    Released: September 07, 2010
    JOURNALS FREE ACCESS
    The formation of amino acid from maleic acid and ammonia aqueous solution by 60Co γ-ray irradiation has been studied.
    The irradiated solutions were analyzed by paper electrophoresis and amino acid analyzer. Aspartic acid was identified and estimated by spectrophotometry. The yield of aspartic acid formed was found to be dependent on the radiation dose and the concentrations of maleic acid and ammonia. The reaction mechanism was proposed as the combination of radicals induced by radiation.
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  • Tatsuya TUCHIDA, Toshiyuki OKA
    1969 Volume 18 Issue 5 Pages 175-180
    Published: May 15, 1969
    Released: September 07, 2010
    JOURNALS FREE ACCESS
    Measurements of renal glomerular filtration rate using sodium iothalamate-131I by sample counting method in 39 cases and external counting method in 20 cases were investigated and compared with thiosulfate clearance by a single injection method performed simultaneously.
    First, in sample counting method, after intravenous injection of SI-131I, samples of blood were obtained at 30 and 40 minutes, sample of urine collected from 20 to 50 minutes. The activity of 131I in plasma and urine were measured in well type scintillation counter in counts per milliliter per minute. All clearances were calculated by the formula C=UV/P, where C in the plasma clearance in ml/min, V the urine volume in ml/min, U the urine activity and P the plasma activity (epm) .
    Second, in external counting method, plasma disappearance curve obtained by external monitoring over the head or the heart during 60 minutes.
    This curve could be described by two components satisfying the equation Y=Ae-b1t+Be-b2t, where Y is the concentration of isotope at time t, A the time zero intercept of terminal slow component with slope b1, B the time zero intercept of early rapid component with slope b2. Also the above equation conducts being based on assumed two compartment model, then the dose of SI-131I injected into compartment one is mixed and distributed. Next diffused into compartment two and consist in excretory and intercompartmental clearances in compartments system. Clearance (C) was calculated from the plasma curve by the formula derived by Sapirstein and co-workers.
    C=I×r1r2/Ar2+Br1ml/min.
    Where 131I equals injected radioactivity of dose and A, γ1, B and γ2 is obtained from the slopes and intercepts of the components of the corrected curve as plotted on semilogarithmic graph paper.
    Correlation coefficient for sample counting method and simultaneous thiosulfate clearance was 0.89, and for external counting method similarly 0.86, These counting methods seem as useful clinical examination of measurement of glomerular filtration rate, especially external counting method without urine collection and multiple venepunctures.
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  • [in Japanese]
    1969 Volume 18 Issue 5 Pages 181-193
    Published: May 15, 1969
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • [in Japanese]
    1969 Volume 18 Issue 5 Pages 194-202_1
    Published: May 15, 1969
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • 1969 Volume 18 Issue 5 Pages 202
    Published: 1969
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • 1969 Volume 18 Issue 5 Pages A955-A520
    Published: May 15, 1969
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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