RADIOISOTOPES
Online ISSN : 1884-4111
Print ISSN : 0033-8303
ISSN-L : 0033-8303
Volume 30 , Issue 7
Showing 1-14 articles out of 14 articles from the selected issue
  • Toshio ISHIYAMA, Takashi MATSUMURA, Yoshihide HONDA, Yuichiro KIMURA
    1981 Volume 30 Issue 7 Pages 361-365
    Published: July 15, 1981
    Released: July 21, 2010
    JOURNALS FREE ACCESS
    RuNO-Chelex 100 resin, [R·RuNO (OH) (OH2) ] was prepared by the reaction of RuNO-chloro complex with Chelex 100 resin, and it is expected that aqua and hydroxo groups contained in RuNO-Chelex 100 resin act as adsorption sites for glycinate or alaninate anion by ligand-exchange reaction. The equilibrium constants, Keq, of 1: 1 complex formation reactions of RuNO-Chelex 100 resin with glycine and alanine were found to be 96.3±5.76 and 82.6± 2. 69, respectively. The inhibitive effect of glycine and alanine on adsorption of (RuO2 (NO2) - (NO3) (H2O) NO) -to anion exchange resin increased in the order of glycine alanine. It was observed that the inhibitive effect was dominated by Keqof RuNO-Chelex 100 resin with glycine and alanine.
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  • Takashi SUZUKI, Katsuya NAKAGAWA, Yoko KANNO, Satoshi ICHINOE, Norio T ...
    1981 Volume 30 Issue 7 Pages 366-371
    Published: July 15, 1981
    Released: September 07, 2010
    JOURNALS FREE ACCESS
    The urinary aldosterone (ALD) was measured by aldosterone RIA kit and the following results were obtained.
    (1) We have known that ten percent solution of bovine serum albumin (BSA) instead of free serum ALD is used as the diluent of the urine in aldosterone RIA kit.
    (2) The upper limits of free ALD, HCl-ALD and β-glucuronidase ALD in the urine diluted with 10% BSA were 1.6, 9.0 and 9.5μg/dl respectively.
    (3) The values of urinary conjugated HCl-ALD and R-glucuronidase ALD were approximately 3.5 times and 4 times as much as that of free ALD respectively.
    (4) A good correlation was obtained among the results of three methods (HCl-ALD, βglucuronidase ALD and free ALD) .
    (5) No difference was found in the values of the urinary ALD in the healthy subjects and the patients with essential hypertension, kidney diseases and acute liver diseases.
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  • Takashi SUZUKI, Katsuya NAKAGAWA, Teizo ITO
    1981 Volume 30 Issue 7 Pages 372-378
    Published: July 15, 1981
    Released: September 07, 2010
    JOURNALS FREE ACCESS
    Plasma concentration of progesterone (P), 17a-hydroxyprogesterone (17a-P), 11-desoxy-cortisol (S), cortisol (F), 11-desoxycorticosterone (DOG), corticosterone (B), aldosterone (ALD), dehydroepiandrosterone free (DHA f ), dehydroepiandrosterone-sulfate (DHA-s) and testosterone (TEST) were measured in 26 essential hypertension (E.H.) and 6 primary aldosteronism (P.A.) before, 30 min. and 60 min. after the intravenous infusion of ACTH 250 fig.
    Seven E.H. patients were similarly studied in the condition of low and high sodium intake and plasma renin activity (PRA) was also measured at the same time.
    P.A. showed significantly higher ALD than that of E.H., whereas DHA f and DHA-s levels of these patients were lower than that of E.H.
    In men with E.H., TEST level showed step down response to ACTH.
    Low sodium intake induced a marked increase of ALD and PRA in E.H.
    In low sodium intake other mineralocorticoids such as DOG and B showed high value at 60 min (20% t value) after ACTH infusion.
    From these observations, it was suggested that the mineralocorticoids have a good response to ACTH in low sodium intake rather than high sodium intake, especially ALD has a cleary augmented response to ACTH.
    On the other hand, PRA showed only a reserve response to ACTH infusion.
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  • Akira SHIMURA, Tomomitsu HIGASHI, Hiromi WAKAO
    1981 Volume 30 Issue 7 Pages 379-384
    Published: July 15, 1981
    Released: September 07, 2010
    JOURNALS FREE ACCESS
    Following its discovery by Edwards and Hayes (1969), the propensity of 67Ga to accumulate preferentially in malignant tissues has been studied at diverse levels, not only for its importance in diagnostic imaging but also for its fundamental biological interest. The biodistribution of 67Ga citrate seems to be strongly influenced by the concentration of serum iron and the unsaturated iron-binding capacity (UIBC) .
    Recently, it was found that the clearance of 67Ga from blood and the attainment of high tumor to normal soft-tissue concentration ratios are accelerated if the serum iron concentration is high.
    The present investigation was undertaken in order to study the relationships between the change of the concentration of serum iron and 67Ga accumulation in the tumor and soft-tissues in mice bearing Ehrlich's ascited tumor. The following results were obtained.
    (1) The uptake of 67Ga in the tumor and soft-tissues except bone was decreased compared with controls if the concentration of serum iron was elevated by Fesin (saccharated ferric oxide) administered prior the injection of 67Ga.
    (2) The urinary excretion of 67Ga was considerably increased if the concentration of serum iron was elevated by Fesin administered prior the injection of 67Ga.
    The results are consistent with the hypothesis that binding 67Ga to transferrin is very important to the accumulation of 67Ga in tumor and soft tissues.
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  • Tomomitsu HIGASHI, Akira SHIMURA, Hiromi WAKAO
    1981 Volume 30 Issue 7 Pages 385-390
    Published: July 15, 1981
    Released: July 21, 2010
    JOURNALS FREE ACCESS
    Gallium-67concentrates in a variety of soft-tissue and tumor, however the accumulation is not specific for malignant tumor. The increase the tumor to non-tumor ratio is important to improve the quality of the tumor image.
    It has been recently found that the clearance of 67Ga from blood and the attainment of high ratios of the tumor to normal soft-tissue concentrations are accelerated, if the serum iron concentration is high.
    The present investigation was, therefore, undertaken in order to study the effect of administered iron after injection of 67Ga on the accumulation of 67Ga in the tumor tissue of mice bearing Ehrlich's ascited tumor. The following results were obtained.
    The accumulations of 67Ga in the tumor and soft-tissues were slightly decreased compared with controls after ferric acid saccharated (Fesin) administration 3, 6 and 24 hours after injection of 67Ga. However, the tumor to blood ratio (T/B) in each group treated with Fesin was considerably increased because the clearance of 67Ga from the blood is accelerated. The large tumor to blood ratio (T/B) would be advantageous for tumor scanning.
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  • Bo-Li Liu, YU-TAI Jin, Minoru MAEDA, Masaharu KOJIMA
    1981 Volume 30 Issue 7 Pages 391-393
    Published: July 15, 1981
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • Akira YOSHITAKE, Takeshi KAMADA, Iwao NAKATSUKA
    1981 Volume 30 Issue 7 Pages 394-396
    Published: July 15, 1981
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • Ryuji OHNISHI, Shoji NISHIYAMA, Koji NABESHIMA, Toru SUEMATSU, Michima ...
    1981 Volume 30 Issue 7 Pages 397-400
    Published: July 15, 1981
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • Chikako ISHII, Yutaka MORI, Yuichi HATA, Naofumi KATSUYAMA, Minoru FUJ ...
    1981 Volume 30 Issue 7 Pages 401-403
    Published: July 15, 1981
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • Shigeru KOSUDA, Toshikazu SANMIYA, Isoo KITAGAWA, Yaeko TAKAGI, Atsush ...
    1981 Volume 30 Issue 7 Pages 404-406
    Published: July 15, 1981
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • Shigeko KURIHARA, Sachiko KOIKE, Kiyoko KUSAKABE, Hiroshi DEMURA, Hiro ...
    1981 Volume 30 Issue 7 Pages 407-409
    Published: July 15, 1981
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • Otomaru SATO
    1981 Volume 30 Issue 7 Pages 410-419
    Published: July 15, 1981
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • Subcommittee for Standardization of Radionuclide
    1981 Volume 30 Issue 7 Pages 420-423
    Published: July 15, 1981
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • 1981 Volume 30 Issue 7 Pages A2139-A210
    Published: July 15, 1981
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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