RADIOISOTOPES

Radiation Dosimetry with Zener Diode

Shigeki NAKAMURA, Shinichi OKAMOTO

1985 Volume 34 Issue 9 Pages 467-472
Published: September 15, 1985
Released on J-STAGE: September 07, 2010

DOIhttps://doi.org/10.3769/radioisotopes.34.9_467

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Commercially available zener diodes have been tested for applying them to dosimetry of cobalt-60 γ-rays. The response observed, i.e. the relation between irradiated dose and radiation-induced change in the breakdown voltage of the zener diode, have shown good linearity under the conditions: (1) The diode is kept below 50°C during irradiation. (2) Measurement of the change in the breakdown voltage were made at the liquid-nitrogen temperature. A typical diode of Toshiba 05Z18 has been found to be useful for measuring irradiation doses between 15.48 kC/kg (6×10⁷R) and 2.58 MC/kg (1×10¹⁰R) with a fading less than 10% till 1000 hours after irradiation. This method of dosimetry has been applied to the measurement of the spatial distributions of γ rays inside a basket-type cobalt-60 source, and reasonable results have been obtained. It can be concluded from the present experiment that the radiationinduced change in the breakdown voltage of the zener diode offers a convenient and inexpensive method of radiation dosimetry.

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Investigation of Groundwater Flow in a Deep Aquifer by the Activable Tracer Method

Ken TABEI, Tsutomu SUGIURA, Otomaru SATO, Fumihiko MAEDA, Makoto KUROY ...

1985 Volume 34 Issue 9 Pages 473-479
Published: September 15, 1985
Released on J-STAGE: September 07, 2010

DOIhttps://doi.org/10.3769/radioisotopes.34.9_473

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In order to select most suitable activable tracers for investigation of groundwater flow (70°C) in an aquifer, loss of indium and dysprosium compounds (nitrate and chelate) by adsorption on rock, sampled from an underground aquifer at a depth of about 1000 m, was first examined by both batch and column methods.
Next, the groundwater flow in an aquifer was investigated by injecting 1 kg of Dy-chelating complex salt (Dy-DTPA) and In-DTPA as activable tracers into a reducing well at a distance of 112 m from a producing well. Dy-DTPA and In-DTPA of 0.9μg/l and 0.4μg/l at maximum concentrations, respectively, were detected in the groundwater when 11000m³ and 21000m³ waters were pumped up from the producing well.
Dy-DTPA has proved to be a useful tracer for the investigation because of relatively small loss whereas a considerable fraction of In-DTPA appears to be lost by adsorption or chemical decomposition.

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Synthesis of N-Methyl and N-¹¹C-Methyl Spiperone by Phase Transfer Catalysis in Anhydrous Solvent

Hiroyoshi OMOKAWA, Akira TANAKA, Mayumi IIO, Yoshiaki NISHIHARA, Osamu ...

1985 Volume 34 Issue 9 Pages 480-485
Published: September 15, 1985
Released on J-STAGE: September 07, 2010

DOIhttps://doi.org/10.3769/radioisotopes.34.9_480

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Spiperone, a butyrophenone neuroleptic drug, has been used in binding studies of dopamine receptors.
Långström et al, developed N-¹¹C-methyl spiperone, and, in cooperate with Wagner et al., made it possible to visualize the distribution of dopamine receptors in the human brain in vivo. In this paper, we independently developed another synthetic method of N-¹¹C-methyl spiperone using the phase transfer catalyst in an anhydrous solvent.
Separation of the product is feasible only by passing the reactant solution through a Millipore filter and injecting it onto high pressure liquid chromatography (HPLC) .
The time required for the synthesis and purification of N-¹¹C-methyl spiperone from ¹¹C-methyl iodide and spiperone was 20 min. Radiochemical yield exceeded 35% against ¹¹C-methyl iodide without correcting decay of the radioactivity.

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SOL-Detectability of Liver SPECT

—Analysis of the structure of ROC-curve—

Toru MATUMOTO, Takeshi A. IINUMA, Tatuo ISHIKAWA, Yukio TATENO, Noboru ...

1985 Volume 34 Issue 9 Pages 486-492
Published: September 15, 1985
Released on J-STAGE: September 07, 2010

DOIhttps://doi.org/10.3769/radioisotopes.34.9_486

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The purpose of this study is to evaluate the clinical efficacy of liver SPECT (single photon emission computed tomography) . The two examinations were performed in 76 cases with SOL (space occupying lesion) and 58 normal cases. The results of the image reading by the planar image only (PS) and that of the image reading by the combination of PS and SPECT (PS+SPECT) were analyzed by ROC (receiver operating characteristic) analysis. The ROC curves showed that SPECT appears to reduce the number of results which were equivocal by the image reading of PS only. The detectability of SPECT for SOL in the left lobe of liver was less than that of PS without statistical significance. However, the performance of SPECT for SOL in the right lobe of liver was significantly better than that of PS.

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Scintigraphy in the Small Animals Using a Human Gamma Camera

—Evaluation of bone scintigraphy in the rat mandible and maxilla—

Masayuki KANEKO, Hideaki TAKANO, Yoichiro HOSOKAWA, Takashi OHNISHI, K ...

1985 Volume 34 Issue 9 Pages 493-496
Published: September 15, 1985
Released on J-STAGE: September 07, 2010

DOIhttps://doi.org/10.3769/radioisotopes.34.9_493

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In order to obtain clear scintigrams of small animals, some improvements were brought on a pinhole collimator. Then, using a human gamma camera with this collimator improved, bone scintigraphy was attempted in the rat mandible and maxilla, experimentally to examine the desirable conditions of scintigraphy. The most desirable bone scan images were obtained under the conditions that the pinhole was 1.5 mm in diameter, the distance between the collimator and the object was 0 cm, and the exposure was 400.

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The Method for Making Plane Sources Using Ion-Exchange Membrane

Hiroyuki MURAKAMI, Makoto YOSHIDA, Kazuyoshi BINGO, Takanobu SUGO, Jir ...

1985 Volume 34 Issue 9 Pages 497-500
Published: September 15, 1985
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.34.9_497

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The Development of the High Sensitive Thyroid Stimulating Hormone Radioimmunoassay

Atsuo NAGATA, Masako Ueno, Susumu MATSUMOTO, Yoshito HARA

1985 Volume 34 Issue 9 Pages 501-504
Published: September 15, 1985
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.34.9_501

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Hepatogram Deconvolution Analysis Using ^99mTc-pyridoxyl-methyl-tryptophan

Masato YAMASHITA, Etsuro NAKAJIMA

1985 Volume 34 Issue 9 Pages 505-507
Published: September 15, 1985
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.34.9_505

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Clinical Application of Radioreceptor Assay

Junji KONISHI

1985 Volume 34 Issue 9 Pages 508-517
Published: September 15, 1985
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.34.9_508

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The 6th Quality Control Survey for Radioisotope in vitro Tests in Japan, 1984 (II)

Subcommittee for Radioisotope in vitro Test

1985 Volume 34 Issue 9 Pages 518-528
Published: September 15, 1985
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.34.9_518

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[title in Japanese]

1985 Volume 34 Issue 9 Pages A65P-A96M
Published: September 15, 1985
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.34.9_A65P

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