RADIOISOTOPES
Online ISSN : 1884-4111
Print ISSN : 0033-8303
ISSN-L : 0033-8303
Volume 38, Issue 8
Displaying 1-7 of 7 articles from this issue
  • Yasuo TAKEHARA, Motoichiro TAKAHASHI, Haruo ISODA, Masao KANEKO, Tsune ...
    1989 Volume 38 Issue 8 Pages 335-338
    Published: August 15, 1989
    Released on J-STAGE: September 07, 2010
    JOURNAL FREE ACCESS
    Lately, the criteria of brain death is being discussed. Cerebral scintigram, especially scintigraphic evaluation of brain death by dynamic study, has been previously reported. Cerebral imaging using radiolabeled amines such as123I-IMP N-isopropyl-p-iodoamphetamin (IMP) or99mTc d, l-hexamethyl-propyleneamine oxime (HMPAO) offers a significant information of brain death by the finding of“non visualized brain”. However, the dynamic scintigram acquired during the bolus injection of99mTc-HMPAO provides an additional information of brain death by classical“hot nose sign”. 99mTc-HMPAO is able to be administered relatively in a large amount of dose. This cerebral perfusion tracer is lipophilic and remains in the central nervous system, which characterize its role as an reliable indicator of cerebral blood flow. As a result, this compound became suitable for the non-invasive study of brain circulation when the diagnosis of brain death is uncertain. We report a case of brain death in which diagnosis was made by the classical“hot nose sign”in dynamic scintigraphy performed when99Tc-HMPAO was injected as well as the SPECT which showed a lack of cerebral visualization at the equilibrium state. As far as we are informed, this additional procedure used in the diagnosis of brain death has not reported before. The importance of performing a dynamic scintigram at the administration of99mTc-HMPAO is also discussed in this report.
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  • B. POLAIAH, P. CHANDRASEKHAR REDDY, B. RANGAMANNAR
    1989 Volume 38 Issue 8 Pages 339-341
    Published: August 15, 1989
    Released on J-STAGE: September 07, 2010
    JOURNAL FREE ACCESS
    A substoichiometric radiochemical method has been developed for the determination of microgram amount of cobalt utilizifig potassium ethyl xanthate as a reagent. The effect of pH and the foreign ions on the substoichiometric extraction of its ethyl xant hate complex into chloroform was also studied. Microgram amounts of cobalt was determined with an average error of ±1.42%.
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  • B. POLAIAH, P. CHANDRASEKHAR REDDY, B. RANGAMANNAR
    1989 Volume 38 Issue 8 Pages 342-343
    Published: August 15, 1989
    Released on J-STAGE: September 07, 2010
    JOURNAL FREE ACCESS
    A substoichiometric radiochemical method has been developed for the determination of thallium (I) employing potassium ethyl xanthate as a reagent. The effect of pH and foreign ions on the substoichiometric extraction ofTl (I) ethyl xanthate complex into chloroform was studied. Tens of micrograms amount ofTl (I) was determined with an average error of ±1.35%.
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  • Masayuki KANEKO, Terumichi KOBAYASHI, Hideaki TAKANO, Takashi OHNISHI, ...
    1989 Volume 38 Issue 8 Pages 344-346
    Published: August 15, 1989
    Released on J-STAGE: September 07, 2010
    JOURNAL FREE ACCESS
    Thyroid scintigraphy in rats and mice with 99mTC and 123I was attempted to examine whether this modality might be used in small animals and to describe the possibilities of its application in examing experimentally produced thyroid diseases. A human gamma camera with a pinhole collimator improved for small animals was used for imaging. Thyroid images with 99mTc were obtained 20 minutes after injection and those with 123I were 24 hours after administration.
    All the scintigrams, although those obtained from mice with 99mTc displayed overlapped salivary gland images, demonstrated sufficiently clear images in size and shape, which showed that thyroid scintigraphy in small animals should be applicable in examining experimentally produced thyroid disases.
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  • Hiroshi YOSHIDA, Kimiichi UNO, Satoshi MINOSHIMA, Keiko IMAZEKI, Takem ...
    1989 Volume 38 Issue 8 Pages 347-350
    Published: August 15, 1989
    Released on J-STAGE: September 07, 2010
    JOURNAL FREE ACCESS
    The biodistribution of nanometer-sized colloidal particles (nanocolloids, Solco-Basle Ltd.) was examined in six rabbits with turpentineinduced abscesses in the masculature of their hind legs.
    A 99mTc labelled colloids with a mean particle size less than 100nm were administered to each rabbit intravenously. The biodistribution of the tracer was studied with a gamma camera 1, 3, and 24 hours after injection. Prominent uptakes were demonstrated in the liver, spleen, bone marrow, kidneys, and urinary bladder. On the other hand, the abscess and surrounding inflammatory edema was depicted as unclearly margined faint hot spot.
    Subsequently, the rabbits were sacrificed and activity per gram tissues were counted with a well-type gamma counter. Although the results were almost in agreement with a gamma camera study, it was noticed the activity counts in the abscess was significantly higher than that of control muscle.
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  • Ken-ichi HASEGAWA
    1989 Volume 38 Issue 8 Pages 351-357
    Published: August 15, 1989
    Released on J-STAGE: July 21, 2010
    JOURNAL FREE ACCESS
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  • 1989 Volume 38 Issue 8 Pages A57P-A82M
    Published: August 15, 1989
    Released on J-STAGE: July 21, 2010
    JOURNAL FREE ACCESS
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