The authors comparatively studied effects of γ-rays and some heavy metal treatments on mobility of water flea Daphnia magna according to the OECD Guideline for Testing of Chemicals, which is generally used for ecotoxicity evaluation of chemicals. The 50% effect dose at 24 hours after γ-irradiation (ED50/24h) was 1 600 Gy. The 50% effect concentrations following 24 hours exposure for manganese, nickel and copper (EC50/24h) were 990, 180 and 3.3 μM, respectively. The Gy-equivalent factors (=ED50/24h/EC50/24h) were therefore calculated as 1.6, 8.9 and 480 for manganese, nickel and copper, respectively. These factors indicate that toxicity of these metals to D. magna can be ranked in an order of Mn<Ni<Cu. This toxicity rank shows a similar trend to that evaluated previously in the experimental model ecosystem (microcosm) consisting of three species of aquatic microorganisms. However, there was a noteworthy difference in the toxicity ranks obtained from the D. magna immobilization test and the microcosm test, suggesting that ecotoxicity ranking should be carried out by integrated evaluation on the basis of various ecotoxicity tests.
Background : In our center, clinical trial with32P began in June 2001. This new medical treatment method is expected to be a promising cure with few side effects. To establish the validity of a new treatment method, it is necessary to evaluate the efficacy of treatment and secure the safety of interventional cardiologists. This study evaluates the exposure dose of the interventional cardiologists during intracoronary radio-therapy with32P (5.5 GBq) . Method : We measured the amount of beta ray irradiation using a rate of H' (0.07, 0°), detained in the centering catheter. Then, we measured braking radiation dose using H' (10, 0°) of32P, with the original phantom. Results : Exposure dose of interventional cardiologists during this new treatment was 2.0 μSv/procedure as an effective dose. The radiation dose at the intracoronary radiotherapy is relatively less compared with conventional X-ray medical radiation techniques. However, the interventional cardiologist is exposed mainly when a radioactive source is outside of a patient [H' (10, 0°) : 1.0 μSv and H' (0.07, 0°) : 100μSv] . Conclusion : They should take a distance from a source or protect beta ray during the transit of32P from SDU (source delivery unit) to patient and return to SDU after therapy.
The amount of quench is measured with liquid scintillation spectrometer changing the temperature of the sample. The range of the changed temperature is between 0°C and 35°C. The measurement is carried out for three kinds of unquenched standard, two quenched standards and fifteen kinds of scintillation cocktail and the mixed sample. It is confirmed that the amount of quench increases for all samples as the temperature rises. The influence of the changed amount of quench to the quench correction is examined.