A few of roof the pieces were subjected to therrnoluminescence (TL) -dating. In annual dose estimation, natural radioactive nuclides were determined by a γ-ray spectrometry, so that the difference of natural radionuclide concentrations made these roof tiles into more than three groups of their kiln sites. Then quartz extracts from the roof tiles were followed to the evaluation of naturally accumulated dose after the firing events by mean of the SAR/RTL methods. Two ages estimated from these RTL-accumulated doses and annual doses gave an excellent agreement with the predicted age, although one sample showed different behavior of RTL-glowcurves depending on kinds and energies of radiation, resulted in finally scattering age. Additionally, every ages evaluated from feldspar fractions offered relatively young ages even using far-RTL measurements, as well as BTL-ones. Both quartz and feldspar extracts from the same roof-tile were compared from aspects of TL-sensitivity using signal/noise ratios after artificial irradiation of 50 Gy. As a result, BTL from feldspar fractions possessed high sensitivity, giving highest one from orthoclase, whereas RTL from quartz and far-RTL from feldspar fractions indicated extremely weak sensitivity, amounting to three order faint intensity. Finally, it was concluded that contamination of feldspar into quartz fraction will be negligibly small contribution in the case of RTL-measurement, while such feldspar-contaminated quartz fraction will cause erroneous result in the case of BTL-dosimetry.
The effect of ultraviolet irradiation on elasticity and viscosity of skin of the pig has been measured. The changes have been examined both in normal and catechin applied skin. The increase in the coefficient of elasticity and viscosity has been observed after hydrogen peroxide application, while catechin has found to be protective for these changes. In this experiment, it has been concluded that catechin is able to scavenge the highly reactive hydroxyl radical.
The objective of this study was to assess the cost-effectiveness of antithyroid drug (ATD) therapy vs. radioiodine therapy (RIT) vs. subtotal thyroidectomy (STT) by calculating expected lifelong cost and utility based on Graves' disease patients' responses to questionnaires using a decision-tree sensitivity analysis and relevant variables. The decision-tree sensitivity analysis to determine expected lifelong cost and utility in Graves' disease patients was designed on the basis of the 4 competing strategies consisting of: (1) ATD therapy plus RIT strategy, (2) ATD therapy plus STT strategy, (3) low-fixed-dose (185 MBq) RIT alone strategy, and (4) high-fixed-dose (370 MBq) RIT alone strategy. One-way sensitivity analysis was designed in the ATD therapy plus RIT strategy, for replacement with RIT in place of ATD, ranging from a 100 incidence of ATD side effects to 30%. The low-fixed-dose RIT alone strategy was least costly, and the high-fixed-dose RIT alone strategy most costly. The lifelong utility of high-fixed-dose RIT alone strategy with a 5% rate of discounting was highest (lifelong utility for 30 years : 15.2/patient), and the utility of the ATD plus RIT strategy with 100 side effects of the ATD was lowest (14.1/patient) . The cost-effectiveness ratio was lowest (\5 008/utility) in a low-fixed-dose RIT alone strategy. In conclusion, a low-fixed-dose RIT alone strategy is preferred treatments in view of cost-effectiveness ratio, and RIT should be used more widely in Japan.
Extremely low-background γ-ray spectrometry is applied to the determination of blank levels of nuclides (7Be, 60Co, 134Cs, 137Cs, 210Pb, 226Ra, 228Ra and234Th) in various chemical reagents and carriers, including Ba and Pb chemicals, BaSO4from natural barite, contrast media for medical use, and Pb in an old roof tile. Barite shows less contamination with226Ra compared with the Ba chemicals (6 - 90 mBq/g-Ba in Ba reagents, 0.7 -1.5 mBq/g-Ba in barite) . 210Pb contamination is notable in all Pb reagents, but not in the roof tile. In CsCl reagent, 134Cs, 137Cs and234Th (238U) are found to be negligible. Using the least-contaminated carrier reagents, the coprecipitation method is successfully employed to the simultaneous measurement of low-level activities of these nuclides in seawater sample.