巻号一覧
9 巻 (1968)
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9 巻, 3 号
選択された号の論文の10件中1～10を表示しています
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綜説
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肥後 理, 堀内 篤, 滝沢 義矩, 天木 一太1968 年 9 巻 3 号 p. 391-398
発行日: 1968年
公開日: 2008/10/20
ジャーナル 認証ありPDF形式でダウンロード (1273K)
臨床研究
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(II)潜在性脾腫と卵巣機能不全藤井 高明, 松本 幸三, 中田 功, 本津 浩一, 清水 宏1968 年 9 巻 3 号 p. 399-407
発行日: 1968年
公開日: 2008/10/20
ジャーナル 認証あり1. Unpalpable splenomegaly was proved by tomographic splenography in 38 male and 144 female cases with idiopathic hypochromic anemia, at the rates of 78.9% in male and 53.9% in female. In all these cases, the spleen was impalpable. Such unpalpable splenomegaly however, was not realized in iron deficiency anemia caused by loss of blood due to stomach ulcers.
2. The majority of female patients with idiopathic hypochromic Anemia, judging from the reduced excretion of uric hormone and the abnormal basal body temperature, curve, were found to be suffering from ovarian insufficiency.
3. In cases which showed good response to the treatment with chalybeates, marked improvement was noted in endocrinological functions, such as increased excretion of uric adrenocortical and sex hormone, and more normal basal body temperature curve.
However, when the administration of chalybeates was discontinued before the ovarian function was sufficiently improved, relapse of the anemia was frequent. At the same time most cases with delayed response to this treatment were also found to have ovarian insufficiency.抄録全体を表示PDF形式でダウンロード (705K) -
永井 清保, 小林 司郎1968 年 9 巻 3 号 p. 408-413
発行日: 1968年
公開日: 2008/10/20
ジャーナル 認証ありIt is generally accepted that the reticulocytes which are capable of synthesizing hemoglobin are the erythrocytes with the longest life span between erythroblasts and normocytes.
But, it is uncertain whether all reticulocytes formed under erythropoictic stimuli reveal the similar property or not.
In an attempt to clarify this question, the chronological changes in osmotic fragility after bleeding was studied on the reticulocytes and erythocytes of various cell age.
While major part of reticulocytes were observed to be of increased osmotic resistance, some fragile reticulocytes were detected after bleeding.
Furthermore, the specific globulin coating of reticulocytes was proved by the antiglobulin reaction.
From the above data, some of reticulocytes subjected to both active hemoglobinization and cell damages during the sequestration in the spleen are speculated to be destroyed in an early period of time after further maturation.抄録全体を表示PDF形式でダウンロード (588K) -
名尾 良憲, 村上 義次, 牧 泰, 小幡 裕, 町井 彰, 片野 てい子, 小島 靖, 岡田 寛, 高松 道雄1968 年 9 巻 3 号 p. 414-422
発行日: 1968年
公開日: 2008/10/20
ジャーナル 認証ありAn interesting case of chloroma was reported.
A 27 years-old male patient showed a pattern of chronic myelogenous leukemia in his initial stage and finally developed to acute trans-formation toward green tinge tumors, which were proved in ribs and appendix as autopsy.
This case was a rare example in which the very beginning picture could be studied. At the same time, a statistical review was made on the frequency of leukemia with tumor formation in our hospital and in Japan as the whole.
Fifty-two cases of leukemia with tumor formation were reported in Japan since 1950, including 11 cases in our Metropolitan Toshima Hospital and chloroma, monocytric leukemia, lymphocytric leukemia and myelogenous leukemia were frepuent in this order.
Our 11 cases of leukemia with tumor formation including two chloroma were found by autopsy among 23 cases of leukemia. These two chloromas showed almost the same picture in their hematological figure as well as clinical course.抄録全体を表示PDF形式でダウンロード (962K) -
畔柳 武雄, 斎藤 昌信, 狩野 庄吾1968 年 9 巻 3 号 p. 423-428
発行日: 1968年
公開日: 2008/10/20
ジャーナル 認証あり2-ethyl-3 (4-hydroxybenzoyl)-benzofuran (Fragivix) is a synthetic flavonoid derivate and its capillary permeability reducing activity is 16 times as strong as that of rutin. The clinical effect of Fragivix was studied on 33 patients with purpura.
The adminstration of Fragivix (600 mg/day) to 7 patients with allergic purpura resulted in a marked improvement of purpura and in a reduction of an increased capillary fragility. Fragivix (600 mg/day) was administered to 15 patients with idiopathic thrombocytopenic purpura. Eleven patients showed slight or moderate clinical improvement of purpura and a moderate reduction of an increased capillary fragility. Fragivix (600 mg/day) was admisted to eleven patients with hematological diseases associated with thromobocytopenic purpura. A slight or moderate clinical improvement of purpura was observed in 8 of 11 patients.
Five among 33 patients who received the admistation of daily dose of 600 mg of Fragivix showed a slight gastrointestinal disturbance. However, this side effect of Fragivix was abolished by reducing daily dose of Fragivix to 300 mg. No effect of Fragivix on the liver function was demonstrated.抄録全体を表示PDF形式でダウンロード (453K)
症例
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幸山 達, 福田 保夫, 福田 肇, 花田 基典, 服部 絢一1968 年 9 巻 3 号 p. 429-435
発行日: 1968年
公開日: 2008/10/20
ジャーナル 認証ありA 22-year-old girl was admitted to our hospital with complaints of gingival swelling, petechiae on her right thigh and anemia of one month duration. Prior to her admisson she had taken diphenyl-hydantoin sodium (Aleviatin), 500 g in total, for epiletic seisure for 5 years. On admission, physical examination revealed neither hepatosplenomegaly nor lymphadenopathy, but slight anemia, gingival swelling and petechiae.
Haematological study showed normal leukocyte count (6400) with monocytosis (25%) in the peripheral blood and (47%) with a few polynucleated erythroblasts in bone marrow specimen. Histological study of biopsy specimen from the swelled gingival and the ileum, also proved abundance of monocytic series.
All these data told the possibility of monocytic leukemia with nuance of erythroleukemia for this case. One month after her admission, impetigo on her head and face, slight increase in serum-globulin and later hepatomegaly of 2 to 4 finger breadths developed. Corticosteroids and 6MP were given in the last week with out effect. She died of intracerebral bleeding about 11 months after the apearance of gingival swelling.
It seemed very likely that this leukemia, as seen in atomic bombed survivours, might have been possibly invited through unknown mechanism in the course of recovery from the hypoplastic anemia this state was missed in this case.抄録全体を表示PDF形式でダウンロード (759K) -
—症例の検討と本邦報告例の文献的考察—和田 武雄, 大原 弘通, 山田 弘仁, 百石 文一, 石沢 光郎, 島田 孝, 坂本 真一1968 年 9 巻 3 号 p. 436-444
発行日: 1968年
公開日: 2008/10/20
ジャーナル 認証ありA case of paroxysmal nocturnal hemoglobinuria (PNH), 39 years old male, was reported. Biochemical analyses on the constituents of lipid and phospholipid of the erythrocyte revealed increase of total lipids and especially of palmitic acid in contrast of decrease of linoleic acid. Although a coarse granular change in the ghoast membrane was observed electron-micrscopically in the patient erythrocyte, the specific structual abnormalities of the erythrocyte stroma in PNH were hardly determined for the moment. Activity of acetylcholinesterase of the erythrocyte was also decreased remarkably. The increase of the hemolysis and hemolytic factors in plasma were discussed according to lieratures, and 54 cases of PNH in Japan including the present case were riviewed.抄録全体を表示PDF形式でダウンロード (858K) -
池崎 英文1968 年 9 巻 3 号 p. 445-450
発行日: 1968年
公開日: 2008/10/20
ジャーナル 認証ありA 25-year-old, snack bar maid, who had no contributory family and past history, was found to have enlargement of liver, proteinuria, and pregnancy (4 months) on January 4, 1967. She was admitted to Department of Gynecology of our hospital on January 10 for therapeutic abortion. In the afternoon of the following day suddenly she was obtunded and in the evening revealed miliary rash on the face and extremities. She was transferred to Department of Medicine on January 12.
Physical examination on admission showed exanthemata on the face and extremities with purpura edema, ascites, superficial lymphadenopathy and hepatomegaly, but no anemia. Peripheral blood showed 75,600 of WBC with 35.6% of atypical immature forms with negative peroxidase and poorly positive PAS-staining. Myelogram showed 31.6% of atypical cells.
Gestational toxicosis, uremia and lymphatic leukemia were suspected, but the patholosic cells were different from the lymphoblasts in lymphatic leukemia. She died of bronchopneumonia on the 12th hospital day.
Autopsy materials showed the features of reticurosarcoma, in which Sarcoma cell infiltrations were observed around hair matrices by histological study of the skin with miliary rash.抄録全体を表示PDF形式でダウンロード (1461K) -
安部 英1968 年 9 巻 3 号 p. 451-455
発行日: 1968年
公開日: 2008/10/20
ジャーナル 認証ありA 11 years old white male was bitten twice at his right hand by an ordinary “non-poisonous” snake, natrix tigrina, and came to hospital carrying this snake. He had bite wounds on the slightly swollen hand back without particular general complaints. His blood cell counts were within normal ranges, having platelets at the level of 180,000/mm3.
Scarcely 30 hours after his admission, large suggillations were observed on upper and lower extremities together with hematuria and followed by epistaxis which could not be stopped so easily. The blood clotting time was longer than 30 minutes, the fibrinogen content in plasma being 60 mg/dl, and the prothrombin time could not be measured as the reaction sample did not clot.
The hemorrhagic diathesis was worsened more and more, and his neck also swollen with tender enlarged lymph nodes. At the same time, secretion containing a few stripes of blood ran off through his right nasal lacrimal duct. His blood showed pretty high elevation of fibrinolytic activity and remarkable hypocoagulability, so that blood transfusion was performed, but it was obliged to be stopped because of side effects, such as fever, exanthem, etc., and then he was given ε-aminocaproic acid intravenously with fibrinogen and antihistamic drugs under the diagnosis of defibrination syndrome.
Thereafter his clinical symptoms and laboratory findings began to turn to better side gradually and he was discharged on his 26th hospitalization day with complete recovery.
In this paper the action of snake venom and the mechanism developing defibrination syndrome were also discussed concerning on this case.抄録全体を表示PDF形式でダウンロード (440K)
例会
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1968 年 9 巻 3 号 p. 463-480
発行日: 1968年
公開日: 2008/10/20
ジャーナル 認証ありPDF形式でダウンロード (1864K)
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