In the case of a full-blown fire occurs in a large fuel oil storage tank over 34 m in diameter, fire-foam is planned to be discharged at 10 000 to 40 000 L/min from large capacity foam monitors. However, the fire-foam is easily flown by wind and thermal updrafts from the burning oil surface. In order to estimate the trajectory of the discharged water and/or fire-foam, three-dimensional simulation model based on the Moving Particle Semi-implicit (MPS) method has been developed with the disintegration model of water mass employing the Rosin-Rammler distribution, the foaming model of a foam solution and wind turbulence model. We conducted a series of the water and fire-foam discharge experiments with discharge flow rate of 1 500 L/min in order to perform quantitative evaluation of simulation results. The flying behavior, maximum range and major footprint (landing zone) were simulated with 1 to 11% difference in comparison with measured data including wind turbulence. Therefore, these simulation models enable to predict the discharge characteristics of fire-foam during flight and to estimate the optimal discharge conditions considering the effect of wind and distance of a monitor position to a tank.