SANGYO EISEIGAKU ZASSHI
Online ISSN : 1349-533X
Print ISSN : 1341-0725
ISSN-L : 1341-0725
Volume 57, Issue 6
Displaying 1-5 of 5 articles from this issue
Original
  • Takumi Takano, Shigeru Suzuki, Ikuto Tsukiyama, Hiroko Saito
    Article type: Original
    2015 Volume 57 Issue 6 Pages 275-285
    Published: 2015
    Released on J-STAGE: December 18, 2015
    Advance online publication: August 12, 2015
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    Objectives: Anti-cancer drugs are harmful to healthy persons. In recent years, occupational exposure to anti-cancer drugs has become a major concern to health care workers. To address this issue, a smear method was developed to measure widely using anti-cancer drugs depositing on the floors, safety cabinet surfaces, and tables in hospital. Methods: Ten kinds of widely used anti-cancer drugs, paclitaxel, vincristine, docetaxel, vinorelbine, irinotecan, methotrexate, oxaliplatin, cyclophosphamide, gemcitabine and fluorouracil were collected by smearing material surfaces with methanol impregnated cellulose filter paper and/or polypropylene nonwoven. The collected anti-cancer drugs are extracted in 5 ml of 0.01% (v/v) hydrazine/methanol solution by sonication. The extracted solution was filtered and concentrated to prepare 1ml of sample solution. Then, the anti-cancer drugs in the sample solution were simultaneously measured by LC/MS. Results: The anti-cancer drugs excepting fluorouracil spread on P-tile surface were measured with recoveries of 37–101% and standard deviations (SD) of 1.8–19%. All 10 of the anti-cancer drugs on a stainless steel plate surface were measured with the recoveries of 35–111% and SD of 1.3–11%. Conclusions: Using this smear method, 9 or 10 kinds of widely used anti-cancer drug residues in hospital, possibly exposed to health care workers, were grasped.
  • Tomoe Fukumura, Katsushi Yoshita, Masaji Tabata
    Article type: Original
    2015 Volume 57 Issue 6 Pages 286-296
    Published: 2015
    Released on J-STAGE: December 18, 2015
    Advance online publication: September 04, 2015
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    Objectives: The purpose of this study was to understand the actual state of life hours (working time, sleep time, and time of meal intake) and dietary habits of male shift work employees, and to elucidate the impact of working arrangements and dietary habits on their physical condition and health problems. Methods: The subjects were 187 male employees (aged 18–64 years) working for an industrial company in Toyama prefecture. We used a self-administered questionnaire to assess dietary habit, lifestyle habits, and life hours at the time of a periodic health examination in April 2013. The subjects were grouped based on their working condition (i.e., day shift, late shift, and late-night shift) into two groups of day shift (n = 107) and shiftwork (n = 80). The proportion of time spent sleeping and feeding was determined in half hour increments, and the incidences of skipping meals (breakfast, lunch and dinner) and midnight snack intake were calculated for each working condition. We also examined the association between the frequency of eating and physical condition for each working condition. Results: The state of life hours of the shiftwork group during the day was similar to that of the day shift group. However, the workers’ state of life hours, incidences of skipping meals, and midnight snack intake varied considerably when working at the other shift times. In the shiftwork group, regardless of the working patterns, the BMI and % body fat of the group that ate more than three times a day were significantly lower than those of the group that ate less than twice a day. Conclusions: The results of the present study suggest that it is difficult to ensure the time and opportunity for meals for shift workers. We consider that it is necessary to prevent them skipping of meals, and to support a proper dietary intake during the night.
Field Study
  • Satoru Kanamori, Yuko Kai, Kayo Kawamata, Mari Kusumoto, Tomoko Takami ...
    Article type: Field Study
    2015 Volume 57 Issue 6 Pages 297-305
    Published: 2015
    Released on J-STAGE: December 18, 2015
    Advance online publication: August 12, 2015
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    Objectives: The purpose of this study was to determine the association between the presence of occupational health nurses and health promotion activities, relative to the number of employees, and the health promotion policies of the companies. Methods: We investigated 3,266 companies with at least 50 employees listed on the Tokyo Stock Exchange. Questionnaires were sent by mail, and employees in charge of health management or promotion were asked about health promotion activities at their own worksites. Logistic regression analysis was performed with each type of health promotion activity (nutrition, exercise, sleep, mental health, smoking cessation, alcohol consumption reduction, and oral health) as dependent variables, and the presence of an occupational health nurse as the independent variable. The results were adjusted for the type of industry, total number of company employees, presence of company health promotion policies, and the presence of an occupational health physician. Results: Responses were received from 415 companies (response rate: 12.7%). Occupational health nurses were present at 172 companies (41.4%). Health promotion activities such as (in order of frequency) mental health (295 companies, 71.1%), smoking cessation (133, 32.0%), exercise (99, 23.9%), nutrition (75, 18.1%), oral health (49, 11.8%), sleep (39, 9.4%), and alcohol consumption reduction (26, 6.3%) were being conducted. Setting worksites with no occupational health nurse as a reference, the odds ratios of each health promotion activity of a worksite with one or more occupational health nurses were calculated. The odds ratios of mental health (2.43, 95% confidence interval: 1.32–4.48), smoking cessation (3.70, 2.14–6.38), exercise (4.98, 2.65–9.35), nutrition (8.34, 3.86–18.03), oral health (4.25, 1.87–9.62), and alcohol consumption reduction (8.96, 2.24–35.92) were significant. Stratified analysis using the number of worksite employees, 499 or fewer and 500 or more, also showed significantly higher odds ratios of smoking cessation, exercise, and nutrition activities at worksites of both groups. However, the odds ratios were significant for mental health and oral health activities only at worksites with 499 or fewer employees. Conclusions: At worksites of listed companies around Japan, those with an occupational health nurse carried out more health promotion activities such as nutrition, exercise, mental health, smoking cessation, alcohol consumption reduction, and oral health than those without, even after adjusting for scale of the company and presence of health promotion policies. This result suggests that the posting of an occupational health nurse to a worksite is associated with the conduct of health promotion activities.
  • Isamu Kabe, Yasuo Koga, Takeshi Kochi, Hiroyuki Miyauchi, Aoi Minozoe, ...
    Article type: Field Study
    2015 Volume 57 Issue 6 Pages 306-313
    Published: 2015
    Released on J-STAGE: December 18, 2015
    Advance online publication: September 04, 2015
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    Objectives: Otoacoustic emission (OAE) testing is not widespread in Japanese industrial health. This study examined the association between hearing thresholds (HTs) and OAEs among workers exposed to noise in actual workplaces. Methods: In two metal products manufacturing factories, 34 workers with noise exposure in the workplace (exposure group, mean age 40.6 ± 9.4 years), and 9 workers with no noise exposure (control group, 49.0 ± 14.3 years) were surveyed. The time-weighted average (LAeq) and maximum (LAMAX) of environmental noise monitoring (ENM), and the time-weighted average (LTWA) and sound exposure level (LAE) of personal noise monitoring (PNM) were measured for each subject at the same time. As hearing effect indicators of noise exposure levels, HTs (0.5, 1, 2, 4 and 8 kHz) and distortion product OAEs (DPOAEs) (2, 3 and 4 kHz) were performed before and after 5 days of work. The results of the ENM, PNM, HTs and OAEs were compared between the groups using Student’s t test, and their correlations were investigated using Pearson correlation coefficients. Results: Noise exposure levels of the exposure group were significantly higher than those of the control group. In the exposure group, LAeq, LAMAX, LTWA and LAE were respectively 84.5 ± 4.1 dB(A),89.5 ± 6.3 dB(A), 83.4 ± 4.7 dB(A) and 153.1 ± 15.7 dB(A), and in the control group, they were 53.2 ± 2.6 dB(A), 56.4 ± 2.4 dB(A), 67.8 ± 5.6 dB(A) and 119.5 ± 5.6 dB(A). There was no difference between hearing effect indicators (HTs and OAEs) before and after work in either group. There was no correlation between the noise exposure level (LAeq, LTWA, LTWA and LAE) and HTs or OAEs, but there was a significant correlation between the HTs and OAEs at most of frequencies. The HTs and OAEs of subjects with noise-induced hearing loss (NIHL) were significantly lower than those of subjects without NIHL. Conclusions: This study revealed there is a significant correlation of the HTs and OAEs before and after 5 days of work. In the future, OAE is expected to be used as a screening test of hearing management of noise-exposed workers in Japan.
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