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Volume 28 (1976)
- Issue 6 Pages 549-
- Issue 5 Pages 437-
- Issue 3 Pages 175-
- Issue 2 Pages 87-
- Issue 1 Pages 1-
Volume 28, Issue 6
Displaying 1-8 of 8 articles from this issue
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Hisao SAKO1976 Volume 28 Issue 6 Pages 549-559
Published: November 01, 1976
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSFrom the view of transplantation immunology, a mammalian pregnancy could never be explained without a peculiar mechanism, because an embryo and its appendices might be recognized as a hybrid consisted of two different histoincompatible antigen. This present study was made an attempt to elucidate changes in maternal cell-mediated immune status associated with gestation, parturition and puerperium by the analysis of response of maternal circulating immunocompetent cells in PHA-containing whole blood cultures, and serum factor affecting maternal cellular immunity.
The results were as follows:
1) From the begining of gestation to puerperium, the reactivity of maternal lymphocyte to PHA demonstrated a characteristic pattern.
2) The characteristic alteration of cell-mediated immunity in the mother was referred mainly to the change of lymphocyte-subpopulation such as T-cell and B-cell count per unit volume of blood.
3) Inhibitory effect of maternal serum on the DNA synthesis of lymphocyte during gestational course became enhanced gradually with the progress of gestation.
4) A brisk release of T-cells from the thymolymphatic tissue into the blood stream and a transient diminution of the serum inhibitory effect were occurred before the onset of labour pains.
5) Moreover, serum obtained from the placenta and adjacent areas of the feto-maternal junction contained a significantly higher level of immunologic inhibitory activity than that in peripheral venous blood.
From these findings, “zyklus gravidarum immunologica materi” was advocated associated with gestation and such a reversible change shown in maternal peripheral blood was suggested to reflect a diluted shadow of dynamically altered immune status in feto-maternal junction.
In conclusion, the local milieu of the feto-maternal junction where serum changes of maternal cell-mediated immunity are markedly pronounced, plays an important role not only in maintaining normal gestation but also in the initiation of labour.View full abstractDownload PDF (1472K) -
Scanning Electron Microscopic StudyMichio KINOSHITA, Hisamichi TAKEGUCHI, Masaaki TANAKA, Tatsuya ISHIGUR ...1976 Volume 28 Issue 6 Pages 561-574
Published: November 01, 1976
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSThe intraperitoneal infection is a grave complication of the abdominal surgery for infected female sexual organs, but, the incidence and intensity have remarkably decreased by the development of antibiotics. However, massive dosages or random administration of the antibiotics resulted in some adverse effects. Especially, the direct administration of them into the abdominal cavity, for expecting high local concentration in the infected focus, resulted in unfavorable and fatal complications, particularly intraperitoneal adhesions.
We previously reported ultrastructural changes of peritoneal mesothelial cells of mice to foreign bodies, —hen's bile and colloidal silica (Advances in Obstetrics and Gynecology; 28, 205-217, 1976).
In this study, changes of peritoneal mesothelial cells to the 5%, 25% and 50% solution of the antibiotic (Vistamycin) administered into the peritoneal cavity of mice were observed by a scanning electron microscope.
There were no macroscopic peritoneal adhesions in each experimental groups.
Ultrastructure of the surface of mesothelial cells did not show any changes with 5% Vistamycin solution, but with solutions of higher concentration, the surface of mesothelial cells showed some changes, especially, of microvilli which were deformed, shortened and partially disappeared.
It is concluded that the Vistamycin solution of higher concentration, intraperitoneally administered, injures mesothelial cells, possibly to make peritoneal adhesions, but the 5% solution may be used intraperitoneally without severe side effects.View full abstractDownload PDF (18570K) -
Eiji INAMOTO, Yuriko HASHIMOTOT, Toshitsugu TAMURA, Shoji TOMODA, Shin ...1976 Volume 28 Issue 6 Pages 575-579
Published: November 01, 1976
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSRecently, we experienced one case of very rare blood incompatibility in a mother lacking any representation of either the C or the E series of antigen (-D-).
Intrauterine fetal transfusion was performed at the 28th week of gestation, on the basis of serial estimation of maternal antibody and _??_ O. D. of amniotic fluid.
We have confirmed that by adequate serological study and antenatal treatment it can be expected to have a live newborn even in severely sensitized mother with rare iso-immunization.View full abstractDownload PDF (3004K) -
Minoru UEKI, Takashi SANO, Sonosuke DOI, Ryo IKEDA, Chiu-chin SHIH, Hi ...1976 Volume 28 Issue 6 Pages 581-585
Published: November 01, 1976
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSThe developmental and spreading mechanisms of endometriosis externa are a theme of particular interest, and many theories have been proposed in other countries. Although Sampson's endometrial regurgitation theory is predominant, yet there are few reports in detail on the endometrial cells in ascites. From such a point of view, the properties of ascites during and after menstruation were cytologically examined. As a result, intraperitoneal regurgitation of menstrual blood proved to occur in 78% of cases during menstruation, and endometrial cells were detected in 33% of the cases. These ectopic cells were clustered, less degenerated, and cytologically were identical with the endometrium in the secretory phase. The endometrial cells in the peritoneal cavity appeared to survive for relatively long periods, because clusters of endometrial cells were found in a case 22 days afte menstruation, although the cells were degenerated.
From the findings obtained Sampson's theory appeared to contain some truth.View full abstractDownload PDF (2756K) -
Our 14 Cases and Reviewing the Literatures Concerning to the Management of Cervical Carcinoma, Especially Non-Invasive Carcinoma, Associated with PregnancyMasato YAMASAKI, Gaiko UEDA, Yasuko SATO, Masaki INOUE, Keizo HIRAMATS ...1976 Volume 28 Issue 6 Pages 587-591
Published: November 01, 1976
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSFourteen patients with cervical carcinoma associated with pregnancy, including three cases of carcinoma in situ, were seen at Osaka University Hospital between 1963 and 1975. All patients, except for one with a biopsy diagnosis of carcinoma in situ who was followed up and gave birth of full term baby, were treated with primary surgery. Radical hysterectomy with lymphadenectomy was performed in five patients (one with carcinoma in situ, two with stage Ib and two with stage IIb). Radical hysterectomy with lymphadenectomy and radiation therapy were performed in 6 patients (three with stag Ib, one with stage IIa and two with stage IIb). One patient with a conization diagnosis of carcinoma in situ was treated with simple hysterectomy after dilatation and curettage.
Japanese reports of carcinoma in situ of the cervix associated with pregnancy was very few, in comparison with the reported incidence in the English literature. This may be due to the lack of routine cervical cytologic screening during the prenatal period, which was not usually done in Japan. This suggests that routine cervical cytologic screening warrants more consideration as one of the prenatal examination. Furthermore, there should be more reports to clarify the management of the carcinoma in situ associated with pregnancy.View full abstractDownload PDF (625K) -
Hayato Niwa1976 Volume 28 Issue 6 Pages 593-601
Published: November 01, 1976
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSDownload PDF (1205K) -
A Case ReportYoshinori NAKATA, Teruhiko TAMAYA, Norimasa IDE, Tadashi OBATA1976 Volume 28 Issue 6 Pages 603-606
Published: November 01, 1976
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSThe mother of this baby was a 26-year-old, gravida 3, para 1, abortus 1, whose last menstrual period was on Aug. 10, 1973. She took sedatives due to carsickness on Sept. 1. On the next day, the erythema with itching appeared around her neck and anterior chest, and antihistamine drugs & Vitamins were taken. On the 27th of Sept. she complained of slight lower abdominal pain and genital spotting which appeared off and on for the next 2 months, when the gestation was estimated at the 7th week after last menstrual period. She then stayed in bed to prevent an abortion. She had taken care of and received care with absolute rest in bed due to threatened abortion since then. The fetal heart tone was recognized by Doppler at the 14th week of gestation. It was pointed out that the size of the uterus was smaller at the 29th week of gestation. On the 36th week of gestation, she gave birth to a still born baby with a sudden prolapse of the umbilical cord. The infant weighed 1740gr and had the marked anomalies of an absence of external genitalia, complete absence of a left lower leg and an imperforate anus. The autopsy revealed aplasia of both kidneys, left diaphragmatic hernia, atresia of duodenum, and a single umbilical artery. Embryologically, the teratogenic agents may cause major congenital malformation during the fourth to eighth week of gestation. The teratogenic factors of this baby were not proved.View full abstractDownload PDF (2860K) -
Itsuo KIKUYAMA1976 Volume 28 Issue 6 Pages 607-610
Published: November 01, 1976
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSA 73-year-old woman was hospitalized because of lower abdominal distension due to palpable tumors, on 27 Oct., 1975.
She had neither gastrointestinal nor genital symptoms. Although pelvic examination, X-ray examination and ultrasonogram suspected of giant ovarian tumors, subsequent laparotomy disclosed solid tumors which developed exophitically from the jejunum, ileum and uterine cornua. Jejunal tumor measured 25×13×10cm and ileal one 8×6×5cm.
Histology revealed all these tumors were “leiomyoma”.View full abstractDownload PDF (2834K)
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