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Volume 30 (1978)
- Issue 6 Pages 533-
- Issue 5 Pages 417-
- Issue 4 Pages 297-
- Issue 3 Pages 201-
- Issue 2 Pages 93-
- Issue 1 Pages 1-
Volume 30, Issue 2
Displaying 1-6 of 6 articles from this issue
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Naoyuki SHIMOZATO1978 Volume 30 Issue 2 Pages 93-106
Published: March 01, 1978
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSIn order to find the pattern of placenta-originating enzymes, HSAP and LAP activities were measured using the tissue culture of the human placenta. The results were: (1) The values of HSAP in each placenta had an inherent patterns of enzyme in the mechanism of production and release in the placenta. (2) Both HSAP and LAP activities showed low levels under the conditions of low temperature and low oxygen concentration. (3) Both enzymes were decreased by 2, 4-DNP and ouabain. (4) Each enzyme activity was dissociated with antimycin A, rotenone and MIA. (5) On the other hand, both enzymes were increased by ATP. (6) The pattern of AP and LAP in the rat placenta after injection of Act-D or MSP indicated the parallel decrease, but a recovery was observed in LAP.
To establish an effective diagnostic method for placental function using HSAP, the author formulated two expressions to predict HSAP values. (1) Over 94% of measured HSAP values are included within a range of ±15% of error. (2) Many of cases of abnormal pregnancy showed a low level of HSAP, -15% or lower. (3) Prolonged pregnancy with placental dysfunction was able to be distinguishable from “false” prolonged pregnancy. (4) SFD with no maternal ailment was classifiable into three categories on HSAP pattern. (5) In two consecutive pregnancies of same woman, the courses of HSAP were strikingly consistent between the two pregnancies as far as both were normal, on the other hand, the curves of the women of abnormal pregnancies with SFD, twin, anormaly, LFD or toxemic pregnancy tended to show an inconsistent curve of each other.View full abstractDownload PDF (1495K) -
Tsuneo NODA1978 Volume 30 Issue 2 Pages 107-118
Published: March 01, 1978
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSUsing Msp-induced SFD rats, studies were done on their growth and maturity of the liver throughout perinatal courses. (1) Postnatal glycogen level in the SFD liver was lower than that in the control until the 3rd day. (2) Postnatal DNA synthesis rate of the control liver reached the maximum at the 2nd day, but at the 5th day in SFD. Autoradiographic examination revealed same tendency, and also existence of many hematopoietic cells in the 5th-day SFD liver. (3) The liver mitochondrial cytochromes increased rapidly after birth in the control, but those in SFD increased slowly until the 5-7th day and reached the control level at the 10th day. (4) 14C-glycine uptake into protein fraction at the 20th day of gestation in the SFD uterus and placenta was also affected about 30% smaller than that of the control. (5) Utero-placental damages with Msp-blocking, compared with progesterone-induced prolonged pregnancy and maternal starvation during gestation, were considered to have more severe affections on fetal growth.
These results show that utero-placental damage inducing SFD gives some postnatal influences on the liver development, not only on perinatal fetal development.View full abstractDownload PDF (5103K) -
Keiichi KATO, Yoshinori NAKATA, Noboru TAKANO, Toshiki MURAKAMI, Tadas ...1978 Volume 30 Issue 2 Pages 119-124
Published: March 01, 1978
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSIt is well known that prostaglandin (PG) F22α has some effects on steroidogenesis in the ovary. We measured the plasma progesterone after iv injection of PGF22α on various conditions. When PGF22α was injected into immature rats, plasma progesterone was increased in 30 minutes after the injection and was decreased gradually. When PGF22α was injected ntoi the PMS-HCG treated immature rats, plasma progesterone was also increased in 1 hour after the injection. In contrast to above, no elevation of plasma progesterone was detectable after injection of PGF22α in rats under the treatment of prednisolone to suppress the adrenal cortical function. Same result was observed in PMS-HCG and prednisolone treated immature rats. In the next study we used the autoradiographic technic of 3H-PGF2a in mature proestrous mouse. Uptake of 3H-PGF22α in 30 minutes after intraperitoneal injection were detectable in theca cells in the ovary and adrenal cortex. It was suggested that plasma progesterone was increased after the injection of PGF22α in vivo and the adrenal gland was the main organ to produce progesterone.
However we did not detect the histological difference about the maturation of follicles between PMSHCG treated immature rats with the normal adrenal function and those with the suppressed adrenal function. So there is an possibility that there is no relation between the maturation of follicle in the ovary and steroidogenesis by PGF22α.View full abstractDownload PDF (3066K) -
Kanji KASAI, Hideki AOCHI, Masayoshi OSHIMA1978 Volume 30 Issue 2 Pages 125-130
Published: March 01, 1978
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSUntil today, there have been reported many investigationos n human sexual behaviors. Here we presenta new report of statisticali nvestigationo n sexuall ife of infertilec oupleso f whichw ivesw eres eeminglyn ormal accordingt o every clinicalt ests and examinationsh oweverh usbandsw ere diagnosedt o be azospermiab y testicularb iopsy. This investigationw as performedb y interviewa nd anquetew ith those wives before we informed the clinical diagnosis to the female subjects. Our data imply the sexual life which they were actually doing, was far poor and rather actively managed by females comparing with other reports of normal sexual life. Of course there are some therapeutic methods to lead them in conceptions uch as AID but we are so much doubtfuli f these methodsw ould be fundamentacl ure and improvement of their state of matrimony because these attitudes of sexual life seem to be not only a serious problemo f these disadvantagedc ouplesb ut psychosociacl omplexa nd tragedy.View full abstractDownload PDF (824K) -
Part I. Maternal EnvironmentsHideki AOCHI, Masayoshi OSHIMA, Kanji KASAI1978 Volume 30 Issue 2 Pages 131-137
Published: March 01, 1978
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSIn order to promote our understanding of the residents in Shiga prefecture, we tried to investigate their living environments, especially maternal environments and sexual life which are both deeply related with our clinic projects now under going to open in October, 1978. The results we obtained, were divided into two parts, i. e. I. maternal environments and II. sexual life. Here we present the statistical results of the part I, according to the research items;number (s) of delivery, ideal number (s) of child, future plan of conception, actual attitudes of contraception, spontaneous abortion and artificial interruption of pregnancy, consciousness of sex and sex education. 1, 000 random samples were collected from among females who received mass population screening for uterine cancer organized by Seijinbyo Center, Shiga prefecture. Questions by anquete were prepared. According to the results, we cannot pass over the fact that there was easy-going attitude, though seemingly sound, in the females to participate in improving their maternal environments including sex education.View full abstractDownload PDF (1050K) -
—Especially on its Cytological Studies—Hiroyuki MANDAI, Hideyoshi THUBOUCHI, Nobuyuki FUKADA1978 Volume 30 Issue 2 Pages 139-144
Published: March 01, 1978
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSWe observed exfoliated cells of Sarcoma Botryoides of the Vagina. In cytologic findings, we recognized marked cellular and nuclear atypism.
Mcst of the tumor cells are isolated or separated. However, a small number of the tumor cells are crowded without cellular overlapping. Tumor cells tend to have spindle, tape, oval-shaped cytoplasma well stained by light-green.
Cellular border is faintly defined. Nuclear shape is round or oval. Nuclear border is smooth but nuclear membrane is not thick. Nuclear chromatin is slightly increased and show fine granular pattern. Mcst of the tumor cells have one or two enlarged prominent nucleolus.
We observed stripped nucleus, but not observed atypical mitosis, giant cells, multinucliated cells and mucous-secreating cells.
In histologic findings, myxomatous change was characteristic. Therefore, it is difficult to decide whether malignant or not in case of tumorc ells showed myxomatous degeneration. In well preserved tumor cells, it is possible to diagnose Sarcoma Botryoides by recognizing the cellular and nuclear malignant featuers.View full abstractDownload PDF (6753K)
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